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Reposted by Osteoarthritis and Cartilage Journal

Luke Pattison @interlukein.bsky.social · 6d

Great summary of our latest work - a real Team Science effort! 👥 🐭

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 6d

#New in #OAC ! The sphingolipid sphingomyelin 34:1 is upregulated in the synovial fluid of those with OA. Work from @phar.cam.ac.uk shows that SM34:1 causes inflammatory pain in mice, inducing neuronal hyperexcitability.
@psalmotoxin.bsky.social
@interlukein.bsky.social
@mayadannawi.bsky.social

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Reposted by Osteoarthritis and Cartilage Journal

Troels Kjeldsen @tkjeldsen.bsky.social · 9h

Link to paper published in
@oacjournal.bsky.social here: pubmed.ncbi.nlm.nih.gov/40712915/

Booster sessions for maintaining the effect of neuromuscular exercise and progressive resistance training in hip osteoarthritis: 12-month follow-up from a multicenter cluster-randomized controlled tri...

Clinicaltrials.gov (NCT04714047).

pubmed.ncbi.nlm.nih.gov

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 2h

October's #EditorsChoice is on #guthealth

📈 Higher relative abundance of hashtag#alistipessenegalensis and alterations in tryptophan metabolites like indoleacrylic acid are associated with hand hashtag#osteoarthritis

✋ Access full-text and all their awesome figures here: lnkd.in/gPU3RNv7

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 6d

www.sciencedirect.com/science/arti...

The osteoarthritis associated sphingolipid sphingomyelin 34:1 causes inflammatory pain in mice

Osteoarthritis (OA) has a multifactorial pathogenesis, pain being the main symptom driving clinical decision making. Dysregulation of multiple mediato…

www.sciencedirect.com

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 6d

#New in #OAC ! The sphingolipid sphingomyelin 34:1 is upregulated in the synovial fluid of those with OA. Work from @phar.cam.ac.uk shows that SM34:1 causes inflammatory pain in mice, inducing neuronal hyperexcitability.
@psalmotoxin.bsky.social
@interlukein.bsky.social
@mayadannawi.bsky.social

1 2 4

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 7d

Are you a creative scientist?🧐
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 9d

#New this month in #OAC . Translocator protein 18 kDa (TSPO) plays an important role in #OA occurrence and development. Emapunil targeting TSPO improves OA by modulating #macrophage polarization and #inflammation through the CD14/TLR4/LY96 pathway.
🔗
www.sciencedirect.com/science/arti...

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 13d

#New in #OAC This study by Xiao et al. demonstrates that YAP plays a critical role in subchondral bone remodeling and targeting the YAP-Hhip axis through regulation of Hh-Gli1 signaling in Gli1+ osteogenic progenitors could inhibit OA progression! 🐭
www.sciencedirect.com/science/arti...

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 20d

🌟 Four other conditions that should be considered in the differential diagnoses of early-stage symptomatic knee #osteoarthritis (EsSKOA)

1️⃣ Patellofemoral pain
2️⃣ Meniscus injuries
3️⃣ Collateral ligament injuries
4️⃣ Inflammatory arthritis

Read free at lnkd.in/gvKY77uB

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Reposted by Osteoarthritis and Cartilage Journal

Ewan St. John Smith @psalmotoxin.bsky.social · 22d

Excited to be part of this guest editorial team: if you are looking for a home for your research on pain mechanisms in osteoarthritis, submit away 😃 #PainResearch

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 28

📢 Call for Papers
OAC is excited to announce a Special Issue on Pain Mechanisms in Osteoarthritis.
www.sciencedirect.com/special-issu...
Submission Deadline: May 15th, 2026

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Reposted by Osteoarthritis and Cartilage Journal

Jamie Collins @colljamie.bsky.social · 21d

New from #OrACORe in @oacjournal.bsky.social: Longitudinal associations between bilateral vs unilateral knee osteoarthritis and physical performance. Contrary to our hypothesis we did not find associations between bilateral disease & worsening physical function
www.sciencedirect.com/science/arti...

www.sciencedirect.com

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · 23d

Participants whose daily activity best matched patterns of high evening activity or very high morning activity had the least risk of developing #slowgaitspeed 🚶‍♂️

🗞️ Read more from Tore et al. oarsijournal.com/article/S1063-…

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Sep 5

NEW in this month's issue 🔥

September's Editors Choice by Akkaya et al. found that diets rich in ultra-processed foods are linked to worse knee #osteoarthritis outcomes especially in women 🍔🍦🍟🍩

👀 Read about this large (n=4403) study for free at: www.oarsijournal.com/article/S106...

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Sep 3

#BasicScience #EditorsChoice
This work by Liao et al. investigated the effects of Tamoxifen in multiple mouse models to better understand its role on bone and cartilage metabolism and endochondral ossification. 🐭
📖Read more:
www.oarsijournal.com/article/S106...

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 28

🌟 #New in #OAC 🌟
Curious to know how Piezo1 deletion protects against TMJOA?
Read this new work by Wang et al.
sciencedirect.com/science/arti...

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 28

📢 Call for Papers
OAC is excited to announce a Special Issue on Pain Mechanisms in Osteoarthritis.
www.sciencedirect.com/special-issu...
Submission Deadline: May 15th, 2026

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 26

#New #Basic #Science in #OAC
How does sex influence the development of #PTOA using a mouse model of mechanical #ACL injury? 📑Check out this work:
www.sciencedirect.com/science/arti...

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 20

Higher fat to muscle ratio (FMR) associated with higher #osteoarthritis incidence 👀 👇

🔢 Data from a large prospective cohort study from the UK Biobank dataset (n=328,549)

Read further in this month's issue from Lou et al.:

www.oarsijournal.com/article/S106...

Associations between total and regional fat-to-muscle mass ratio and osteoarthritis incidence: A prospective cohort study

To investigate the associations between total and regional fat-to-muscle mass ratio (FMR) and incident osteoarthritis among adults.

www.oarsijournal.com

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 20

Curious to know how to use #AI in #OAC? 🧐
elsevier.com/about/polici...

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 18

🔥 How can pharmacists help deliver high-value knee OA care?

📖 Explore the #Capabilities, #Opportunities, and #Motivations of Australian pharmacists in this new study: oarsijournal.com/article/S1063-…"

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 7

🎙️ New #jointaction podcast on all things #methotrexate

Joint David Hunter with guests Robin Christensen, BSc, MSc, PhD Anna Døssing to learn more 👇

Podcast link: www.jointaction.info/podcast/epis...

Editorial link: pubmed.ncbi.nlm.nih.gov/40222629/

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 6

New this month!

🦴 Calcium pyrophosphate deposition disease (CPPD) is associated with increased risk of fractures (Fig. 1 below 👇 )

www.oarsijournal.com/action/showP...

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 4

#August #EditorsChoice #BasicScience
This work by Zapata-Linares et al. uses a dynamic mouse model to assess the positive correlation between OA and increased bone marrow adiposity. 📖 more: www.sciencedirect.com/science/arti...

Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Aug 2

🏃‍♂️‍August's Editor's Choice is on #Taichi

✅ Several benefits associated with #Taichi in this 28 study systematic review that included 1676 OA participants

👀 Read more from Zhao et al. at www.oarsijournal.com/article/S106...

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Osteoarthritis and Cartilage Journal @oacjournal.bsky.social · Jul 30

#New in #OAC MM-II is a dispersion of empty large liposomes which is under clinical development for knee OA. This research by Wechsler et al., aims to decipher the MM-II mechanism of action on the tissue types of the knee joint!
🔗https://sciencedirect.com/science/article/pii/S1063458425008155