Dry anophthalmic socket syndrome (DASS) is a complex and multifaceted condition that commonly affects patients who have undergone enucleation or evisceration and wear an ocular prothesis. The diagnosis and management of DASS poses significant challenges due to the absence of a standardised diagnostic criteria and evidence-based treatment protocol. Though DASS symptoms can be disproportionate to observable clinical signs, patient-reported outcomes and scoring systems remain the cornerstone of its diagnostic framework.

BOSTON — A wearable device designed for eye tracking has also shown promise in noninvasively measuring different aspects of blinking, which could be useful both in the clinic and for research, according to a speaker at Academy 2025. “We know [blink is] an important feature, particularly for ocular surface disease, but what we don’t have is a good, standardized way of looking at blinking within a clinic setting or, indeed, outside of a clinic setting,” Michael Read, PhD, new technologies manager at Eurolens Research at the University of Manchester, said at an

Identifying personal priorities is a crucial first step of a job search, according to Imane Tarib, MD, who spoke on best practices to navigate the ophthalmology job market during a presentation at Real World Ophthalmology. Early-career ophthalmologists should begin looking for a position at least 12 to 18 months before the end of their residency or fellowship, Tarib said. “You’re going to have to find time to take off from your training in order to go and meet people in person,” Tarib said. “If you are in a subspecialty that is in need, or if you want to go to a big city, usually the good

Identifying personal priorities is a crucial first step of a job search, according to Imane Tarib, MD, who spoke on best practices to navigate the ophthalmology job market during a presentation at Real World Ophthalmology. Early-career ophthalmologists should begin looking for a position at least 12 to 18 months before the end of their residency or fellowship, Tarib said. “You’re going to have to find time to take off from your training in order to go and meet people in person,” Tarib said. “If you are in a subspecialty that is in need, or if you want to go to a big city, usually the good

The Albert Einstein College of Medicine Institutional Review Board deemed this study to be exempt from formal review because it used only publicly available, de-identified data from ClinicalTrials.gov. The requirement for informed consent was waived and not applicable, as no patient level data was collected or analyzed. All analyses were conducted in accordance with the Declaration of Helsinki and STROBE guidelines.

To evaluate whether pars plana vitrectomy (PPV) increases the risk of ocular hypertension (OHT) and glaucoma, with particular focus on lens status as a risk modifier.

To identify risk factors in diagnosis of second eye PVD after first eye PVD and subsequent complications.

Vitelliform lesions in pachychoroid disease, risks for endophthalmitis after cataract surgery, OCT biomarkers and nAMD outcomes, sleep–wake disorders and glaucoma, 3-drug regimen for intraocular retinoblastoma.

Eye, Published online: 08 October 2025; doi:10.1038/s41433-025-04047-yCombined pathological, microbiological and virological evaluation of vitreous aspirates: a retrospective evaluation of 374 vitrectomy specimens with non-neoplastic disorders

Background/aims Iris melanoma differs from posterior uveal melanoma in clinical behaviour and location. Situated anteriorly, it is directly exposed to ultraviolet radiation (UVR), unlike posterior melanomas shielded by the lens. However, epidemiological patterns and UVR’s role in iris melanoma development remain poorly understood. Therefore, we investigated long-term incidence trends of iris melanoma in Denmark, focusing particularly on tumour location in relation to sun exposure.Methods We conducted a nationwide retrospective cohort study of patients diagnosed with iris melanoma in Denmark from 1943 to 2021. Population-based data were obtained from national registries and institutional records, with tumours classified by anatomical location as inferior, superior or mixed.Results We included 405 patients. Disease-specific mortality was 3% (12 patients), mainly in American Joint Committee on Cancer c-subcategories with secondary glaucoma and extensive anterior chamber angle involvement. Over the study period, the age-standardised incidence increased substantially. Inferiorly located tumours constituted 58% during 1943–1962 and 84% during 2003–2021 (p

Background The purpose of this study was to define a minimum set of outcome measures for patients affected by non-advanced age-related macular degeneration (AMD).Methods A structured Delphi consensus process was conducted by a panel of worldwide experts in treatment outcome registries, imaging, nutrition and other AMD aspects. The experts answered anonymously to a series of surveys, each followed by a face-to-face meeting to discuss the pooled results. Supporting literature was shared among the group members by a facilitator before each round. Finally, all the results were discussed and the consensus document was created based on the level of agreement between experts.Results Six rounds were conducted until a formal consensus was achieved. Five main sections were identified: demographic characteristics, health factors, functional, imaging and clinical outcomes. A minimum set of 28 outcome measures was subsequently developed and approved by all members. Based on the priority of various items, 24 fields were designated as mandatory, while the remaining were deemed optional. Five items are required only at baseline, 12 are to be assessed annually for changes and the remaining 0 1must be collected at each clinical assessment.Conclusion This newly defined minimum set of outcome measures for non-advanced AMD could be employed in future real-world data collection registries aimed at gathering comprehensive and longitudinally extensive clinical data on a global scale. This may help to elucidate the natural progression of non-advanced AMD and its response to new therapies.

Aims To investigate the effect of time outdoors on myopic shift among premyopic children.Methods Post-hoc analysis was nested in a cluster-randomised trial of the Shanghai Time Outside to Reduce Myopia (STORM) study. 6- to 9-year-old participants without myopia from the STORM study, who wore wristwatches to monitor time outdoors from 2017 to 2018, were included. Participants were all examined with cycloplegic refraction. Daily time outdoors was objectively monitored with the wearable smartwatch. Premyopia was defined as a cycloplegic spherical equivalent (SE) from –0.50 to +0.75 (inclusive) dioptres (D). Myopic shift was SE change from baseline to 1 year follow-up.Results Among 3194 participants (1369 premyopic; mean age 8.2±0.6 years; 49.5% boys), there were no statistical differences between premyopic and hyperopic children in time outdoors (p=0.303). Hyperopes showed reduced myopic shift with increasing outdoor time (plateau at about 120 min/day). However, premyopes exhibited a J-shaped relationship between time outdoors and myopic shift. In comparison to the subgroup with daily time outdoors 120 min/d, although it was still not statistically significant (>120 min/d: 0.04 (95% CI –0.05 to 0.14)).Conclusions Among premyopic children, increased time outdoors has a limited protective effect on myopic shift, suggesting longer duration of time outdoors or additional interventions to prevent or delay myopia onset in this population.

Eye, Published online: 08 October 2025; doi:10.1038/s41433-025-04024-5Response to: ‘Comment on: ‘Incidence and outcomes of post-operative endophthalmitis following elective phacoemulsification cataract surgery, between 2015 and 2022”

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Eye, Published online: 08 October 2025; doi:10.1038/s41433-025-04040-5Incidence and prevalence of mucous membrane pemphigoid with ocular involvement: a retrospective analysis using the TriNetX database

Healio | OSN Section Editor Uday Devgan, MD, performed the first robotic-assisted cataract surgery, according to a press release from Horizon Surgical Systems. “Robotic cataract surgery represents a groundbreaking advancement with a goal of higher precision, safety and customization that far surpasses traditional methods,” Devgan, of Devgan Eye Surgery in Los Angeles, told Healio. “While manual cataract surgery is already highly successful, robotics takes the procedure to the next level. With micrometer-level accuracy, robotic systems can perform delicate tasks with unmatched consistency and

Healio | OSN Section Editor Uday Devgan, MD, performed the first robotic-assisted cataract surgery, according to a press release from Horizon Surgical Systems. “Robotic cataract surgery represents a groundbreaking advancement with a goal of higher precision, safety and customization that far surpasses traditional methods,” Devgan, of Devgan Eye Center in Los Angeles, told Healio. “While manual cataract surgery is already highly successful, robotics takes the procedure to the next level. With micrometer-level accuracy, robotic systems can perform delicate tasks with unmatched consistency and

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Volume 33, Issue 8, October 2025, Page 1511-1512 .

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Eye, Published online: 08 October 2025; doi:10.1038/s41433-025-04071-yPersistent disparities in diabetic retinopathy outcomes among socially deprived individuals despite treatment adherence

Eye, Published online: 07 October 2025; doi:10.1038/s41433-025-04013-8Comparative analysis of generic vision-language models in detecting and diagnosing inherited retinal diseases using fundus photographs

Eye, Published online: 07 October 2025; doi:10.1038/s41433-025-04061-0Endogenous fungal endophthalmitis: international, multicentre, retrospective analysis of clinical outcomes following surgical and medical management, and screening

In the October 2025 issue of Ophthalmology, Gazzard et al1 present the results of the GLAUrious trial, which used a noninferiority design to compare the safety and efficacy of direct selective laser trabeculoplasty (DSLT) to that of conventional selective laser trabeculoplasty (SLT). The trial found that DSLT did not achieve noninferiority to SLT for the primary outcome, which was the mean change in washout intraocular pressure (IOP) between baseline and 6 months (SLT-DSLT, –0.7 mmHg difference between groups; 95% confidence interval [CI]: –2.2, 0.8, P = 0.09 for noninferiority).