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Osvaldo Contreras @osvaldoics.bsky.social · 11d

I’m very excited to be invited to present at “Development Presents…”

Thanks @amjeve.bsky.social

the Node @the-node.bsky.social · 11d

Join us 15 October to hear from two early-career researchers, @osvaldoics.bsky.social & Yinan Wan, working on development across scales.

Chaired by @dev-journal.bsky.social Executive Editor @amjeve.bsky.social.

📅 15 October, 09:00 BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

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Osvaldo Contreras @osvaldoics.bsky.social · 11d

Remarkable conference organized by @asbmbaus.bsky.social up in Brisbane at the University of Queensland.

I was invited to present my latest work as a Keynote Speaker for the Multi-Sonic’s session, and so many thanks for selecting me!

Truly an honour!

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Reposted by Osvaldo Contreras

Allegra Angeloni @angeloniallegra.bsky.social · 22d

SAVE THE DATE! Join us for the 2025 @anzscdb.bsky.social
NSW Branch Cell & Developmental Biology Symposium at the Garvan Institute @garvaninstitute.bsky.social on Wed 5 Nov 2025. Keynote speakers include Dougall Norris, @katequinlan.bsky.social, Silvia Velasco and @ryanlister.bsky.social 🔬🧠🧫

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Osvaldo Contreras @osvaldoics.bsky.social · Sep 5

Honored to present at @ramacgenomics.bsky.social @unsw.edu.au next Tuesday.😃

Martin Smith @martinalexsmith.bsky.social · Sep 5

Some exciting #SingleCell events with #ParseBio coming up this month at @ramacgenomics.bsky.social 🧬

9 Sept: SPLiT-Seq Tech Showcase Seminar 🔗 tinyurl.com/bddc5zc3

15 Sept: Application deadline for discounted Parse Evercode WT Mini v3 Kit promotion 🔗 tinyurl.com/yc84zmfm
📩 [email protected]

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Reposted by Osvaldo Contreras

Martin Smith @martinalexsmith.bsky.social · Sep 5

Don't miss @osvaldoics.bsky.social in the flesh next Tuesday in Sydney

Martin Smith @martinalexsmith.bsky.social · Sep 5

Some exciting #SingleCell events with #ParseBio coming up this month at @ramacgenomics.bsky.social 🧬

9 Sept: SPLiT-Seq Tech Showcase Seminar 🔗 tinyurl.com/bddc5zc3

15 Sept: Application deadline for discounted Parse Evercode WT Mini v3 Kit promotion 🔗 tinyurl.com/yc84zmfm
📩 [email protected]

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Osvaldo Contreras @osvaldoics.bsky.social · Sep 3

Thank you Françoise!☺️

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Reposted by Osvaldo Contreras

Victor Chang Cardiac Research Institute @victorchang.edu.au · Sep 1

We're proud to share Dr Osvaldo Contreras has been awarded a Scale Biosciences Core Lab Grant, from @garvaninstitute.bsky.social Genomics Platform, Scale Biosciences, and Integrated Sciences to further his research into the origins of congenital heart disease that affects one in 100 babies.

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Osvaldo Contreras @osvaldoics.bsky.social · Sep 2

Thrilled to share our new paper: "OpenEMMU: A versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics"!

We've developed a new resource that make this crucial research more accessible, accurate, powerful and low-cost.

www.cell.com/iscience/ful...

OpenEMMU: A versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics

Biochemistry; Cell biology; Developmental biology; Computational bioinformatics

www.cell.com

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Reposted by Osvaldo Contreras

Nitzan Gonen @nitzan-gonen.bsky.social · Jul 27

1/n Very excited to share our recent paper published on
@ScienceAdvances
where we dissect the gene regulatory landscape guiding mouse sex determination!
science.org/doi/10.1126/...
A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!

The gene regulatory landscape driving mouse gonadal supporting cell differentiation

Multiomics analysis revealed the regulatory elements and transcription factors responsible for gonadal sex determination.

science.org

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Osvaldo Contreras @osvaldoics.bsky.social · Jul 28

Congratulations Leo! So well deserved. Looking forward to what comes out of your very own Lab

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Reposted by Osvaldo Contreras

Jeff Farrell @jeffreyafarrell.bsky.social · Jun 13

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

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Osvaldo Contreras @osvaldoics.bsky.social · Jun 18

Well deserved!

Osvaldo Contreras @osvaldoics.bsky.social · Jun 11

www.science.org/doi/10.1126/...

Worth reading

In defense of silly science

A biologist pushes back against attacks on curiosity-driven research

www.science.org

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Osvaldo Contreras @osvaldoics.bsky.social · Jun 4

What’s potentially the first multi-omics study out there? Find it below.

This represents a major step forward into what’s later defined as personalised medicine.

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes: Cell

www.cell.com/cell/fulltex...

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

A personalized medicine pilot study samples a patient's transcriptome, proteome, and metabolome multiple times over the course of 14 months and integrates this information with whole-genome sequence d...

www.cell.com

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Osvaldo Contreras @osvaldoics.bsky.social · May 21

Fantastic work, Leo!

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Osvaldo Contreras @osvaldoics.bsky.social · May 8

So happy about presenting our Pan-Omics work next week!🎉

Thanks for the invite👨🏽‍🔬🙏🏽❤️

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Osvaldo Contreras @osvaldoics.bsky.social · May 6

📢 Today!
National Stem Cell Conversations

🔬 Regulation of Patterning
Qi Zhang: "Molecular mechanisms of epigenetic regulation"
Adrienne Sullivan: "Early GATA3 activity mediates lineage commitment and patterning in human gastrulation"

📅 Wednesday, 7th May 2025 ⏰ Time: 11:00 AM - 11:30 AM AEST

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Osvaldo Contreras @osvaldoics.bsky.social · Apr 26

www.science.org/doi/10.1126/...

Fantastic technological progress!

Deep-tissue transcriptomics and subcellular imaging at high spatial resolution

Limited color channels in fluorescence microscopy have long constrained spatial analysis in biological specimens. We introduce cycle hybridization chain reaction (cycleHCR), a method that integrates m...

www.science.org

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Osvaldo Contreras @osvaldoics.bsky.social · Apr 10

FACS-assisted separation of cells for untargeted proteomics. Working with 10,000 cells per experiment to reveal the proteome of these, using low-input omics👨🏽‍🔬🔭

Thanks to all who make our research possible 🙏🏽✨
@victorchang.edu.au
@garvaninstitute.bsky.social

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Osvaldo Contreras @osvaldoics.bsky.social · Mar 29

www.science.org/doi/10.1126/...

The emergence of human primordial germ cell–like cells in stem cell–derived gastruloids

3D human gastruloids mimic gastrulation and postgastrulation development, forming the three germ layer derivatives and hPGCLCs.

www.science.org

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Osvaldo Contreras @osvaldoics.bsky.social · Mar 17

I used both, notes and Labarchives, and figures and papers. Oh lord lots of time to get things done. AI helps tho

Osvaldo Contreras @osvaldoics.bsky.social · Mar 17

A Piece of Art!

A simple 2.5% Agarose gel with so much information in it.

Fundamental science blows my mind, always 🤯❤️

Osvaldo Contreras @osvaldoics.bsky.social · Feb 28

Third paper submitted of the year 🎉

Extremely grateful to my team and colleagues for the daily fundamental discoveries that pave the way for impact and translation 🙏🏽

Fingers crossed for their consideration and smooth revisions

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Osvaldo Contreras @osvaldoics.bsky.social · Feb 24

What?!

Reposted by Osvaldo Contreras

Osvaldo Contreras @osvaldoics.bsky.social · Jan 22

🚀 Open Science can’t wait! I’m thrilled to share our latest preprint: 𝐎𝐩𝐞𝐧𝐄𝐌𝐌𝐔!

🔬 𝐎𝐩𝐞𝐧𝐄𝐌𝐌𝐔: A versatile, open-source EdU multiplexing methodology for understanding DNA replication and cell cycle dynamics

🔗 Read the preprint here: biorxiv.org/content/10.1...

#OpenEMMU #DNAReplication #CellCycle

OpenEMMU: a versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics

5-Ethynyl-2’-deoxyuridine (EdU) has transformed DNA replication and cell cycle analyses through fast and efficient click chemistry detection. However, commercial EdU kits are expensive, contain propri...

biorxiv.org

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