Lightnews — Scholar-powered news

Pacific Optica @pacificoptica.bsky.social · Aug 20

Check out some sweet Ventana Wide + Cousa imaging.
pacificoptica.com/ventana/

Live raw data over a 3.2 mm wide field-of-view with 16,000 lines/s scanning and submicron resolution. Demo now at @omibs-mbl.bsky.social

Thx @ewadorotaz.bsky.social @mbfbioscience.bsky.social @crisrodtsou.bsky.social !

5 9

Reposted by Pacific Optica

OMIBS @ MBL @omibs-mbl.bsky.social · Aug 19

@pacificoptica.bsky.social @leicamicrosystems.bsky.social @thorlabs.bsky.social

1 1 2

Pacific Optica @pacificoptica.bsky.social · Aug 14

Dover XYR and a Z elevator. dovermotion.com/xy-stages/#m...

1

Pacific Optica @pacificoptica.bsky.social · Aug 14

Scientists explore, measure, gather evidence, figure things out, and share openly. Their work benefits us all.

Demo imaging at MBL/Woods Hole and CSHL this summer. Explore further. pacificoptica.com

1 2

Pacific Optica @pacificoptica.bsky.social · Aug 2

Put whatever objective you want on the Ventana Wide. It will give you the largest field of view with high speed scanning: eg, 3.2mm x 3.2mm with a 10x. Fast, flexible 2p imaging.

Che-Hang Yu is helping MBL courses with this Ventana Wide system pacificoptica.com/ventana/

1 5

Pacific Optica @pacificoptica.bsky.social · Aug 2

Just landed in Woods Hole for summer courses: a Full Ventana Wide system. pacificoptica.com/ventana/ with a Cousa pacificoptica.com/cousa/

www.mbl.edu/education/ad...

www.mbl.edu/education/ad...

Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!

1 2 9

Pacific Optica @pacificoptica.bsky.social · Jul 30

Widespread cortical representations of innate behaviors in the mouse. www.biorxiv.org/content/10.1... Using the Diesel2p pacificoptica.com/diesel2p/, they found that "more directed and unilateral grooming movements had greater cortical associated responses than more
stereotyped bilateral movements"

3

Pacific Optica @pacificoptica.bsky.social · Jul 19

We will start gathering at about 3:00.

Pacific Optica @pacificoptica.bsky.social · Jul 18

吉祥寺日曜日。2-photon, optics, 生ビルと　TexMex 食べ物。 maps.app.goo.gl/xoRrGNX7xvK1... ふるってご参加ください。

maps.app.goo.gl

1 1

Pacific Optica @pacificoptica.bsky.social · Jul 18

吉祥寺日曜日。2-photon, optics, 生ビルと　TexMex 食べ物。 maps.app.goo.gl/xoRrGNX7xvK1... ふるってご参加ください。

maps.app.goo.gl

1 2

Pacific Optica @pacificoptica.bsky.social · Jul 14

No more stitching artifacts. Just image the whole field-of-view, at high resolution, in one pass. The Ventana systems give submicron resolution over huge fields-of-view almost 10 square mm. At high speed. Cover a 3.2 mm x 3.2 mm area in 4k resolution in 0.26 s. pacificoptica.com/ventana/

3

Pacific Optica @pacificoptica.bsky.social · Jul 13

Explore further. pacificoptica.com/diesel2p/

1 1

Pacific Optica @pacificoptica.bsky.social · Jul 12

Cool!! This is an exciting new Neuro AI #NeurIPS competition.

By the way, the large scale 2p data for this NeurIPS competition was taken with a Diesel2p system. pacificoptica.com/diesel2p/

2

Reposted by Pacific Optica

SPIE @spie.org · Jul 8

🌌 Curious how visionary engineering shaped one of humanity’s greatest scientific instruments? Discover the architectural origins of the JWST in this in-depth #SPIE_JATIS article: www.spiedigitallibra...

1 6

Reposted by Pacific Optica

Pacific Optica @pacificoptica.bsky.social · Jun 17

ALERT: New journal club style!

S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.

Hilarious in parts, and fun and chill.

Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...

Non-inertial scan angle multiplier - AI-generated podcast with actual human commentary

YouTube video by Spencer LaVere Smith

m.youtube.com

1 2

Reposted by Pacific Optica

Michelle Itano @michelleitano.bsky.social · Jun 24

So excited to hang the ‘Acknowlegement Guidelines’ poster up in Chapel Hill! Grateful to be part of the community working towards equitable recognition for imaging scientists!!

Read more and download the poster (in 10 languages!): lnkd.in/eSQRugJX

#CreditWhereItsDue
#AcknowledgementGuidelines

1 3 17

Pacific Optica @pacificoptica.bsky.social · Jun 24

Now published in Plos Biology journals.plos.org/plosbiology/...

Pacific Optica @pacificoptica.bsky.social · Jun 23

Animals sense in complex environments, and neuronal responses to olfactory/scent stimuli can be shaped by recent history going back ~ 30 s. Here, Subramanian, Storace, et al. used the Cousa objective pacificoptica.com/cousa/ to neural activity in vivo. doi.org/10.1093/chem... #microscopymonday

1

Pacific Optica @pacificoptica.bsky.social · Jun 23

Multinucleated giant cells (MNGCs) emerge as ovaries age, and are hard to study. Here, Converse, Pritchard, Duncan et al. used 2p imaging with the Cousa objective pacificoptica.com/cousa/ in their comprehensive study of age-associated MNGCs. #microscopymonday www.biorxiv.org/content/10.1...

Pacific Optica @pacificoptica.bsky.social · Jun 23

This system has tons of fascinating tech— optics, detectors, software— so many scientists and engineers collaborated on this international project, enjoy the fruits of their talents!

NSF–DOE Rubin Observatory @vrubinobs.bsky.social · Jun 23

The image offers a stunning variety of objects — from bright stars ranging from blue to red in color, to nearby blue spiral galaxies, to distant red galaxy groups — demonstrating the broad range of science made possible by Rubin data ✨🔭🧪

A sprawling, textured field of galaxies scattered across the deep black of space. It is filled with the delicate smudges and glowing cores of galaxies of many shapes, sizes and colors, as well as the bright multi-colored points of stars. To the lower left is a region filled with the hundreds of golden glittering gems of a distant galaxy cluster. In the foreground, below and right of center, two blue spiral galaxies look like eyes beneath the entangled mass of a triple galaxy merger in the upper right. A few bright blue points of foreground stars pierce the glittering tapestry.

Throughout the image, thousands of galaxies gather in clusters or are spread throughout, like glittering gems strewn on a table. Some are sharp-edged and spiral, like coiled ribbons; others round and diffuse, like polished pebbles. Still others are just smudges of various colors. The background is peppered with pinpoint stars in reds, yellows, and blues, crisp against the velvet black.

1

Pacific Optica @pacificoptica.bsky.social · Jun 19

Thanks, Bruno! ♥️

Reposted by Pacific Optica

Bruno Pichler @brunopichler.bsky.social · Jun 19

Fantastic work (as always) from Che-Hang Yu and colleagues in Spencer LaVere Smith's lab. Very neat method to increase scan speed and/or FOV in 2p microscopy. Commercially available from @pacificoptica.bsky.social. I'd love to build this for a client at some point! www.biorxiv.org/content/10.1...

1 2 9

Reposted by Pacific Optica

NSF–DOE Rubin Observatory @vrubinobs.bsky.social · Jun 17

🚨THIS IS NOT A DRILL🚨We are 6 days away from the world's First Look at images from Rubin! #RubinFirstLook 🔭🧪

NSF–DOE Rubin Observatory will take a new 3200-megapixel image every ~40s, yielding ~20 terabytes of data every night! The deluge of data is about to begin 🌊

Rubin Observatory's car-sized digital camera mounted on the telescope. Seen at an angle face-on, the camera is a long black tube cutting vertically through the top two-thirds of the image. Its giant clear glass lens is visible toward the top. To the left and right of the camera, scaffolding for staff access is set up. The background is an array of black and teal steel, both part of the telescope and beyond as part of the dome.

1 8 39

Pacific Optica @pacificoptica.bsky.social · Jun 17

ALERT: New journal club style!

S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.

Hilarious in parts, and fun and chill.

Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...

Non-inertial scan angle multiplier - AI-generated podcast with actual human commentary

YouTube video by Spencer LaVere Smith

m.youtube.com

1 2

Pacific Optica @pacificoptica.bsky.social · Jun 16

So the optical invariant for scanning is not so invariant!

Here's a link to the preprint. www.biorxiv.org/content/10.1... Be sure to check out the videos online. www.biorxiv.org/content/10.1... Raw data videos included. 9/9

www.biorxiv.org

1

Pacific Optica @pacificoptica.bsky.social · Jun 16

There is a bunch more in the paper, including this variation for doubling the phase modulation off of an adaptive optic element. Limited range on your deformable mirror? Not a problem anymore. 8/9

1