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LabEx ParaFrap @parafrap.bsky.social · 19h

The #EMBOWorkshop : Host–parasite relationship has come to a close! Thank you to all speakers, participants, and organizers for four inspiring days of science, discussion, and human connection. Until next time! 🧫✨

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LabEx ParaFrap @parafrap.bsky.social · 1d

The second poster session is underway at the #EMBOWorkshop : Host–parasite relationship — and the enthusiasm is still as strong as ever! 🔬🧫

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LabEx ParaFrap @parafrap.bsky.social · 1d

Closing lecture by Manoj Duraisingh for the #EMBOWORKSHOP x @parafrap.bsky.social 🎬

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LabEx ParaFrap @parafrap.bsky.social · 2d

🧬 Great energy at the first poster session of the #EMBOWorkshop Host–Parasite Relationships!

Fantastic discussions, new ideas, and inspiring exchanges around cutting-edge parasitology research.

Science thrives through sharing!

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LabEx ParaFrap @parafrap.bsky.social · Jul 18

The deadline of @embo.org EMBO workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" Oct. 5-8 (Les Embiez, France), organized by ParaFrap @parafrap.bsky.social, is extended to July 22.
Don't miss out — only a few places remaining! meetings.embo.org/event/25-hos...

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LabEx ParaFrap @parafrap.bsky.social · Jun 10

💼 PostDoc position (2 years) on Trypanosoma brucei | Bordeaux, France | Lab MFP with Dr. Frédéric Bringaud @univbordeaux.bsky.social @cnrsaquitaine.bsky.social

🔬 Glycerol and differentiation in Trypanosoma brucei

🗓️ Deadline: September 15.
Start: by November 2025

labex-parafrap.fr/fr/emplois/4...

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LabEx ParaFrap @parafrap.bsky.social · Jun 5

📣 Next ParaFrap Webinar: Elisabeth Davioud-Charvet @unistra.fr @cnrs-alsace.bsky.social : "Design of improved plasmodione analogs, chemical tools, and prodrugs to generate oral antimalarial drug candidates for total cure"

🗓️ June 12, 3pm CEST

🎟️ bit.ly/ParaFrapWeb

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LabEx ParaFrap @parafrap.bsky.social · May 15

Reminder : Today, ParaFrap webinar at 15:00 CEST. @parafrap.bsky.social #leishmania #parasite

LabEx ParaFrap @parafrap.bsky.social · May 14

📣 Next ParaFrap Webinar: Paul JENKINS (Team Gerald Spaeth) @pasteur.fr: "Determinants for visceral leishmaniasis progression: lessons from hamster and mouse models" @parafrap.bsky.social

Chairperson: Maryse Lebrun @lebrunlab.bsky.social

🗓️ May 15, 3pm CEST

🎟️ bit.ly/ParaFrapWeb

LabEx ParaFrap @parafrap.bsky.social · May 14

📢 Big Announcement: Registration & abstract submission open for EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by ParaFrap @parafrap.bsky.social @embo.org

🗓️ 5-8 Oct 2025 - Les Embiez Island-France

🔚Deadline: 15 Jul 2025 meetings.embo.org/event/25-hos...

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LabEx ParaFrap @parafrap.bsky.social · May 14

📣 Next ParaFrap Webinar: Paul JENKINS (Team Gerald Spaeth) @pasteur.fr: "Determinants for visceral leishmaniasis progression: lessons from hamster and mouse models" @parafrap.bsky.social

Chairperson: Maryse Lebrun @lebrunlab.bsky.social

🗓️ May 15, 3pm CEST

🎟️ bit.ly/ParaFrapWeb

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LabEx ParaFrap @parafrap.bsky.social · Apr 22

An ISWI-related chromatin remodeller regulates stage-specific gene expression in #Toxoplasma gondii. By Belen Pachano (ParaFrap PhD student) et al., team @hakimi.bsky.social. In @natmicrobiol.nature.com www.nature.com/articles/s41...

Toxoplasma gondii evolved two ISWI remodellers, TgSNF2h and TgSNF2L. TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, s...

www.nature.com

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Reposted by LabEx ParaFrap

Mohamed-Ali HAKIMI @hakimi.bsky.social · Apr 11

A humorous reflection on the first article from my stellar PhD student, Belen Pachano.

communities.springernature.com/posts/open-s...

Open Sesame: The Protein Behind Parasite Stage Switching

communities.springernature.com

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Reposted by LabEx ParaFrap

Freddy Frischknecht @freddyfrischknecht.bsky.social · Apr 3

Live from Tübingen: the one and only Artur Scherf illuminating #Plasmodium var gene expression using his flower model of the infected red cell.

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LabEx ParaFrap @parafrap.bsky.social · Apr 1

📣 Next ParaFrap Webinar: Catherine Lavazec @lavazeclab.bsky.social: "Deciphering the interactions between malaria parasites and erythroblasts" @parafrap.bsky.social @inserm.fr @institutcochin.bsky.social
Chairperson: Artur Scherf

🗓️ April 10, 3pm CEST

🎟️ bit.ly/ParaFrapWeb

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LabEx ParaFrap @parafrap.bsky.social · Mar 11

💼 Associate Professor / Toxoplasma / Bordeaux-France

🎓 Teaching: animal biology, metazoan diversity & phylogeny (Bachelor 1,2,3)

🔬 Research: Apicomplexa parasites, focusing on Toxoplasma gondii. @ MFP Lab (UMR5234) @univbordeaux.bsky.social .

🗓️ Deadline: April 4

labex-parafrap.fr/en/job-offer...

Associate professor l Toxoplama l Bordeaux, France

    Associate Professor : Animal Biology and Parasitology – Host-Pathogen Interactions, Bordeaux, France  Teaching Profile ...

labex-parafrap.fr

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LabEx ParaFrap @parafrap.bsky.social · Mar 10

📣Next ParaFrap Webinar: Mauld LAMARQUE (Team Maryse Lebrun) @umontpellier.bsky.social : "Pleiotropic role of the malaria parasite PP1 phosphatase during P. falciparum life cycle" @parafrap.bsky.social
Chairperson: Maryse Lebrun @lebrunlab.bsky.social

🗓️ March 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb

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LabEx ParaFrap @parafrap.bsky.social · Feb 26

New study in @biorxivpreprint.bsky.social : "A novel #Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis". By Rokhaya Thiam, ParaFrap PhD student (Team Yvon Sterkers) #parasite #science

bioRxivpreprint @biorxivpreprint.bsky.social · Feb 20

A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis https://www.biorxiv.org/content/10.1101/2025.02.18.638795v1

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LabEx ParaFrap @parafrap.bsky.social · Feb 25

Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules: @Cell Reports @cellpress.bsky.social . ParaFrap team involved in this study: Nicolas Blanchard (Infinity Lab, Toulouse) #toxoplasma www.cell.com/cell-reports...

Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules

Cebrian et al. demonstrate that the Golgi membrane-associated protein GRASP55 is recruited to late phagosomes in BMDCs. This interaction is essential for trafficking peptide-loaded MHC-I and MHC-II mo...

www.cell.com

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LabEx ParaFrap @parafrap.bsky.social · Feb 25

📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite

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LabEx ParaFrap @parafrap.bsky.social · Feb 13

📣Today-ParaFrap Webinar: Gretchen DIFFENDALL (Team A.Scherf @pasteur.fr): Metabolomics Identifies a Natural Host Cytoadhesion Inhibitor in Asymptomatic #Malaria Cases
@parafrap.bsky.social
Chairperson: A. CLAESSENS @ant1-claessens.bsky.social

🗓️ February 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb

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Reposted by LabEx ParaFrap

LabEx ParaFrap @parafrap.bsky.social · Feb 4

📣 ParaFrap Webinar: Gretchen DIFFENDALL (Team A.Scherf @pasteur.fr): Metabolomics Identifies a Natural Host Cytoadhesion Inhibitor in Asymptomatic #Malaria Cases
@parafrap.bsky.social
Chairperson: Antoine CLAESSENS @ant1-claessens.bsky.social

🗓️ Thursday, February 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb

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LabEx ParaFrap @parafrap.bsky.social · Feb 10

Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in #Plasmodium berghei. In Scientific Reports @SciReports ParaFrap Team: Olivier Silvie rdcu.be/d9iFF

Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei

Scientific Reports - Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei

rdcu.be

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LabEx ParaFrap @parafrap.bsky.social · Feb 10

Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in #Mycobacterium smegmatis. In Communications Biology
@commsbio.bsky.social . ParaFrap team involved in this study: Frédéric Bringaud. www.nature.com/articles/s42...

Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in Mycobacterium smegmatis - Communications Biology

The ATP synthase inhibitor bedaquiline (BDQ) inhibits mycobacterial growth by depleting ATP, with gained tolerance to low BDQ concentrations through metabolic transplantation of trypanosomal SLPHOS pa...

www.nature.com

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LabEx ParaFrap @parafrap.bsky.social · Feb 10

Parasite of the month in Trends in Parasitology: #Trypanosoma equiperdum. By Perrine Hervé, Frédéric Bringaud and Loïc Rivière (ParaFrap Team) @cp-trendsparasitol.bsky.social

Trends in Parasitology @cp-trendsparasitol.bsky.social · Jan 31

Parasite of the Month: #Trypanosoma #equiperdum, the #etiological agent of #dourine, a disease specific to #equids ( #horses #mules #donkeys ) transmitted through #coitus, authored by P. Hervé, F. Bringaud & L. Rivière @univbordeaux.bsky.social @cnrs.bsky.social

authors.elsevier.com/a/1kVtS5Eb1x...

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LabEx ParaFrap @parafrap.bsky.social · Feb 10

Ectopic overexpression of Plasmodium falciparum DNA-/RNA-binding Alba proteins misregulates virulence gene homeostasis during asexual blood development | Microbiology Spectrum | Parafrap team involved in this study: Artur Scherf. journals.asm.org/doi/full/10....

Ectopic overexpression of Plasmodium falciparum DNA-/RNA-binding Alba proteins misregulates virulence gene homeostasis during asexual blood development | Microbiology Spectrum

The malaria parasite Plasmodium falciparum tightly controls the expression of its genes at the epigenetic, transcriptional, post-transcriptional, and translational levels to synthesize essential prote...

journals.asm.org

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