Patrick Phillips
patrickphillips.bsky.social
Patrick Phillips
@patrickphillips.bsky.social
Geneticist at University of Oregon @uoregon. Worms, C. elegans, aging, evolution, genetics, genomics, complex traits. Former provost and interim president. Lab: https://pages.uoregon.edu/pphil/ GScholar: https://scholar.google.com/citations?user=JbH6mVkAAA
This is normally called embellishment, but embellishment has nothing to do with it. The sparkling light has existed in all its brightness from the very beginning in the world of phenomena. 3/3
November 26, 2025 at 5:14 AM
This is why, no matter whether nature or human things are concerned, the artist conceals innumerable priceless gems in a place that common mortals dare not approach. 2/3
November 26, 2025 at 5:14 AM
Lol @mads100tist.bsky.social. We've tried a number things for mass culture over the years, like self-enclosed "worm balls". But the reality is that running for the hills is a young-male's game.
bsky.app
November 7, 2025 at 10:16 PM
November 6, 2025 at 11:14 PM
I don’t need to tell you, but one cool scaffolding idea is to take one example and to return to it at each stage of the course to slowly unpeel the genetics onion. Mouse coat color is perfect for that because you can go from transmission to molecular to biochemistry to population genetics.
September 4, 2025 at 3:30 PM
Bateson and Punnett’s first example was rooster combs, which is cool. Mouse coat color is great because you can tie it directly to molecular function that explains the epistasis. Check out my 2008 NRG paper for examples and pictures. Also plant examples if you are into that kind of thing 😁
September 4, 2025 at 2:58 PM
"Random" variation in just a handful of genes explains differences in reproductive outcomes across genetically identical individuals. It's Ground Hog Day or Midnight Library for worms — if those stories also revealed epigenetic associations (I'm sure they were supposed to be in there someplace).
September 2, 2025 at 11:12 PM
Although other work, which I have also never published, shows that this domain can be much bigger than you would expect. (Other than that Dr. Fermat, how is your research going).
September 2, 2025 at 6:18 PM
The situation that you describe is the physical manifestation of of that more general principle. And of course it will almost always be true within a certain small chromosomal region, say within the confounds of a gene.
September 2, 2025 at 6:16 PM
Something that I discovered as a graduate student, but have never published. Formally, from a statistical point of view, dominance and epistasis are only distinguishable under linkage equilibrium. Otherwise they are confounded.
September 2, 2025 at 6:15 PM