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pdc-lab.bsky.social
De Camilli Lab
@pdc-lab.bsky.social
200 followers 3 following 2 posts
Laboratory of Pietro De Camilli - Department of Neuroscience at Yale University
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pdc-lab.bsky.social
De Camilli Lab @pdc-lab.bsky.social · 9d
"Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C" out now in PLOS Biology
journals.plos.org/plosbiology/...
Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C
VPS13A and VPS13C are bridge-like lipid transport proteins with distinct subcellular localization and function, and their absence is linked with chorea-acanthocytosis and Parkinson's disease, respecti...
journals.plos.org
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pdc-lab.bsky.social
De Camilli Lab @pdc-lab.bsky.social · Apr 10
"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology
rdcu.be/ehbaL
The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage
Nature Cell Biology - Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal...
rdcu.be
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Reposted by De Camilli Lab
scienceofpd.bsky.social
The Science of Parkinson's @scienceofpd.bsky.social · Apr 10
New research from @pdc-lab.bsky.social & collaborators finds that the bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage; #Parkinsons-associated LRRK2 is also recruited but at later stage
www.nature.com/articles/s41...
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