Physiological Reports
@physrep.bsky.social
A peer-reviewed, online, Open Access journal publishing across all areas of physiology. A collaboration between The Physiological Society and the American Physiological Society.
Website: https://physoc.onlinelibrary.wiley.com/journal/2051817x
Website: https://physoc.onlinelibrary.wiley.com/journal/2051817x
The Editors Thank all Authors, Reviewers, Readers, Editorial Board members and Staff for their support of the success of Physiological Reports in 2025!
Best wishes for a Happy festive season and a productive 2026.
@physoc.bsky.social
@apspublications.bsky.social
@wileylifesci.bsky.social
Best wishes for a Happy festive season and a productive 2026.
@physoc.bsky.social
@apspublications.bsky.social
@wileylifesci.bsky.social
December 23, 2025 at 4:39 PM
The Editors Thank all Authors, Reviewers, Readers, Editorial Board members and Staff for their support of the success of Physiological Reports in 2025!
Best wishes for a Happy festive season and a productive 2026.
@physoc.bsky.social
@apspublications.bsky.social
@wileylifesci.bsky.social
Best wishes for a Happy festive season and a productive 2026.
@physoc.bsky.social
@apspublications.bsky.social
@wileylifesci.bsky.social
129S2/SvPas mice are susceptible to #hypertension from dietary #electrolyte manipulation. In a #doxorubicin-induced #proteinuria model, 129S2/SvPas mice proved resistant to proteinuria compared to 129S1/SvImJ mice, and proteolytic processing of #renal #ENaC was not increased
doi.org/10.14814/phy...
doi.org/10.14814/phy...
December 11, 2025 at 10:15 AM
129S2/SvPas mice are susceptible to #hypertension from dietary #electrolyte manipulation. In a #doxorubicin-induced #proteinuria model, 129S2/SvPas mice proved resistant to proteinuria compared to 129S1/SvImJ mice, and proteolytic processing of #renal #ENaC was not increased
doi.org/10.14814/phy...
doi.org/10.14814/phy...
Postprandial #exercise is recommended for people with metabolic disease. This study reports reduced postprandial #insulin and #glucose among young and old active exercisers, with association to #cognitive function and #bodywater compartment ratio.
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#Metabolism #Ageing
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#Metabolism #Ageing
November 26, 2025 at 10:15 AM
Postprandial #exercise is recommended for people with metabolic disease. This study reports reduced postprandial #insulin and #glucose among young and old active exercisers, with association to #cognitive function and #bodywater compartment ratio.
doi.org/10.14814/phy...
#Metabolism #Ageing
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#Metabolism #Ageing
Investigation of #masseter #muscle in #microphthalmia mice (with Mitf mutation and masticatory dysfunction) shows increased myocyte #apoptosis and #fibrosis, reduced masseter muscle mass and low expression of #microRNAs needed for #skeletal muscle development
doi.org/10.14814/phy...
doi.org/10.14814/phy...
November 25, 2025 at 10:15 AM
Investigation of #masseter #muscle in #microphthalmia mice (with Mitf mutation and masticatory dysfunction) shows increased myocyte #apoptosis and #fibrosis, reduced masseter muscle mass and low expression of #microRNAs needed for #skeletal muscle development
doi.org/10.14814/phy...
doi.org/10.14814/phy...
#CarbonMonoxide has #antiischemic and #antiinflammatory effects. This study explores the potential of #CORMA1, a molecule that effects controlled CO release, to protect #kidneys from warm #ischemia and #reperfusion injury in rat and swine models.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
November 17, 2025 at 10:15 AM
#CarbonMonoxide has #antiischemic and #antiinflammatory effects. This study explores the potential of #CORMA1, a molecule that effects controlled CO release, to protect #kidneys from warm #ischemia and #reperfusion injury in rat and swine models.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
New data on #mitochondria Aminoacyl-#tRNASynthetase, DARS2, reports secretion by #airway #epithelial cells in response to #TNFα, and a role in #paracrine signaling resulting in M1 #macrophage like phenotype in recipient THP1 cells.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
November 13, 2025 at 10:15 AM
New data on #mitochondria Aminoacyl-#tRNASynthetase, DARS2, reports secretion by #airway #epithelial cells in response to #TNFα, and a role in #paracrine signaling resulting in M1 #macrophage like phenotype in recipient THP1 cells.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
Deadline approaching!
Call for Papers on “Tissue Fibrosis Through the Life Course and in Transplanted Organs” will close on 31st Dec. 2025!
Including, but not limited to:
Age-related Fibrosis
Organ Fibrosis
Fibrosis in Transplanted Organs
More Info:
physoc.onlinelibrary.wiley.com/hub/journal/...
Call for Papers on “Tissue Fibrosis Through the Life Course and in Transplanted Organs” will close on 31st Dec. 2025!
Including, but not limited to:
Age-related Fibrosis
Organ Fibrosis
Fibrosis in Transplanted Organs
More Info:
physoc.onlinelibrary.wiley.com/hub/journal/...
November 12, 2025 at 10:15 AM
Deadline approaching!
Call for Papers on “Tissue Fibrosis Through the Life Course and in Transplanted Organs” will close on 31st Dec. 2025!
Including, but not limited to:
Age-related Fibrosis
Organ Fibrosis
Fibrosis in Transplanted Organs
More Info:
physoc.onlinelibrary.wiley.com/hub/journal/...
Call for Papers on “Tissue Fibrosis Through the Life Course and in Transplanted Organs” will close on 31st Dec. 2025!
Including, but not limited to:
Age-related Fibrosis
Organ Fibrosis
Fibrosis in Transplanted Organs
More Info:
physoc.onlinelibrary.wiley.com/hub/journal/...
This systematic review examines evidence for #Sexdifferences in human #skeletal #muscle fiber types and the influences of #age, physical activity or muscle group.
doi.org/10.14814/phy...
MyoBlue #Exercise #Ageing #Physiology
doi.org/10.14814/phy...
MyoBlue #Exercise #Ageing #Physiology
November 10, 2025 at 10:15 AM
This systematic review examines evidence for #Sexdifferences in human #skeletal #muscle fiber types and the influences of #age, physical activity or muscle group.
doi.org/10.14814/phy...
MyoBlue #Exercise #Ageing #Physiology
doi.org/10.14814/phy...
MyoBlue #Exercise #Ageing #Physiology
Study of #heartrate variability in two birth cohorts, in Finland or Norway, indicates altered #autonomic regulation in adults born preterm with very low birth weight, especially women, potentially contributing to higher #bloodpressure.
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#Birth #Cardiovascular
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#Birth #Cardiovascular
November 4, 2025 at 10:15 AM
Study of #heartrate variability in two birth cohorts, in Finland or Norway, indicates altered #autonomic regulation in adults born preterm with very low birth weight, especially women, potentially contributing to higher #bloodpressure.
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#Birth #Cardiovascular
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#Birth #Cardiovascular
#TRPC6 channels are implicated in pathogenesis of severe #nephrotic syndromes. This study of TRPC6 in normal physiological #podocyte functions reports roles in #MMP7-shedding of #nephrin ectodomains and #apoptosis.
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#Renal #IonChannels
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#Renal #IonChannels
November 3, 2025 at 10:15 AM
#TRPC6 channels are implicated in pathogenesis of severe #nephrotic syndromes. This study of TRPC6 in normal physiological #podocyte functions reports roles in #MMP7-shedding of #nephrin ectodomains and #apoptosis.
doi.org/10.14814/phy...
#Renal #IonChannels
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#Renal #IonChannels
Retrospective cohort study on effects of #caffeine in persons starting #Sodium-glucose #cotransporter-2 inhibitors, indicates high caffeine consumption may reduce the early decline in estimated #glomerular #filtration rate with SGLT2i therapy.
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#Heart #Kidney
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#Heart #Kidney
October 31, 2025 at 10:15 AM
Retrospective cohort study on effects of #caffeine in persons starting #Sodium-glucose #cotransporter-2 inhibitors, indicates high caffeine consumption may reduce the early decline in estimated #glomerular #filtration rate with SGLT2i therapy.
doi.org/10.14814/phy...
#Heart #Kidney
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#Heart #Kidney
This new invited Review discusses how food-related #gut or #endocrine signals and #microbial #metabolites are detected by vagal pathways in #Interoception mediated regulation of #feeding and #glucose #metabolism.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
October 30, 2025 at 10:15 AM
This new invited Review discusses how food-related #gut or #endocrine signals and #microbial #metabolites are detected by vagal pathways in #Interoception mediated regulation of #feeding and #glucose #metabolism.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
New #Methods article surveys #photophysical and spectral properties of popular #pH-sensing green fluorescent proteins, #pHluorins, including a new member pHluorin4, providing insights to optimize applications in different systems.
doi.org/10.14814/phy...
#GFP #FluorescentProteins #CellPhysiology
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#GFP #FluorescentProteins #CellPhysiology
October 22, 2025 at 9:15 AM
New #Methods article surveys #photophysical and spectral properties of popular #pH-sensing green fluorescent proteins, #pHluorins, including a new member pHluorin4, providing insights to optimize applications in different systems.
doi.org/10.14814/phy...
#GFP #FluorescentProteins #CellPhysiology
doi.org/10.14814/phy...
#GFP #FluorescentProteins #CellPhysiology
This study uses continuous video-recorded transnasal #laryngoscopy and simultaneous #airway pressure measurement to quantify the airflow resistance at these sites during noninvasive #ventilation in healthy adults.
doi.org/10.14814/phy...
#Respiratory
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#Respiratory
October 21, 2025 at 9:15 AM
This study uses continuous video-recorded transnasal #laryngoscopy and simultaneous #airway pressure measurement to quantify the airflow resistance at these sites during noninvasive #ventilation in healthy adults.
doi.org/10.14814/phy...
#Respiratory
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#Respiratory
Comparison of #respiratory regulation and #lung volume in healthy young adults undertaking land-based or aquatic #cycling matched for oxygen uptake (VO2) indicates #exercise in an aquatic environment can be more effective for training the respiratory system
doi.org/10.14814/phy...
doi.org/10.14814/phy...
October 6, 2025 at 9:15 AM
Comparison of #respiratory regulation and #lung volume in healthy young adults undertaking land-based or aquatic #cycling matched for oxygen uptake (VO2) indicates #exercise in an aquatic environment can be more effective for training the respiratory system
doi.org/10.14814/phy...
doi.org/10.14814/phy...
Study of individuals with a permanent #pacemaker and preserved LV #systolic function reports right #ventricle pacing frequency and implantation >60 months to be independently associated with increased cellular and #mitochondria #oxidativestress in PBM cells
doi.org/10.14814/phy...
doi.org/10.14814/phy...
October 3, 2025 at 9:15 AM
Study of individuals with a permanent #pacemaker and preserved LV #systolic function reports right #ventricle pacing frequency and implantation >60 months to be independently associated with increased cellular and #mitochondria #oxidativestress in PBM cells
doi.org/10.14814/phy...
doi.org/10.14814/phy...
#New data that cardiac timing effects on human information processing response speeds are modulated by #bloodpressure but not by #heartrate variability in healthy young adults.
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#Interoception #Cognition #Physiology
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#Interoception #Cognition #Physiology
October 1, 2025 at 9:15 AM
#New data that cardiac timing effects on human information processing response speeds are modulated by #bloodpressure but not by #heartrate variability in healthy young adults.
doi.org/10.14814/phy...
#Interoception #Cognition #Physiology
doi.org/10.14814/phy...
#Interoception #Cognition #Physiology
Effects of short-term low #energy #availability in young adults at rest or exercising: this study identifies alterations in the #serum #metabolome as potential early #biomarkers of low energy availability.
doi.org/10.14814/phy...
#Exercise #Metabolism
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#Exercise #Metabolism
September 30, 2025 at 9:15 AM
Effects of short-term low #energy #availability in young adults at rest or exercising: this study identifies alterations in the #serum #metabolome as potential early #biomarkers of low energy availability.
doi.org/10.14814/phy...
#Exercise #Metabolism
doi.org/10.14814/phy...
#Exercise #Metabolism
#Sensory #electrical stimulation of the upper limb, below motor threshold, is shown to effect sex-related reductions in #spinal #excitability via reciprocal inhibition, providing implications for motor skill learning in #rehabilitation applications.
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#Neurophysiology
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#Neurophysiology
September 25, 2025 at 9:15 AM
#Sensory #electrical stimulation of the upper limb, below motor threshold, is shown to effect sex-related reductions in #spinal #excitability via reciprocal inhibition, providing implications for motor skill learning in #rehabilitation applications.
doi.org/10.14814/phy...
#Neurophysiology
doi.org/10.14814/phy...
#Neurophysiology
#PeerReview Week 2025:
The Editors and staff of Physiological Reports Thank all our Peer-reviewers during 2025 for their commitment to #research quality and integrity and their support of the Journal.
@physoc.bsky.social
@apspublications.bsky.social
#Physiology
#PRW2025
The Editors and staff of Physiological Reports Thank all our Peer-reviewers during 2025 for their commitment to #research quality and integrity and their support of the Journal.
@physoc.bsky.social
@apspublications.bsky.social
#Physiology
#PRW2025
September 19, 2025 at 9:15 AM
#PeerReview Week 2025:
The Editors and staff of Physiological Reports Thank all our Peer-reviewers during 2025 for their commitment to #research quality and integrity and their support of the Journal.
@physoc.bsky.social
@apspublications.bsky.social
#Physiology
#PRW2025
The Editors and staff of Physiological Reports Thank all our Peer-reviewers during 2025 for their commitment to #research quality and integrity and their support of the Journal.
@physoc.bsky.social
@apspublications.bsky.social
#Physiology
#PRW2025
Investigation of physiological mechanisms that influence right-#ventricle and left-ventricle #kinetic #energy, computed from four-dimensional flow by #cardiovascular #MRI, reports increased contractility affects left ventricular kinetic energy in #pulmonary #hypertension.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
September 17, 2025 at 9:15 AM
Investigation of physiological mechanisms that influence right-#ventricle and left-ventricle #kinetic #energy, computed from four-dimensional flow by #cardiovascular #MRI, reports increased contractility affects left ventricular kinetic energy in #pulmonary #hypertension.
doi.org/10.14814/phy...
doi.org/10.14814/phy...
This study of effects of resistance-training on #arterial wall #viscosity reports higher central arterial wall viscosity and lower arterial compliance in resistance-trained men.
doi.org/10.14814/phy...
#Cardiovascular #Exercise #Cardiac #Physiology
doi.org/10.14814/phy...
#Cardiovascular #Exercise #Cardiac #Physiology
September 9, 2025 at 9:15 AM
This study of effects of resistance-training on #arterial wall #viscosity reports higher central arterial wall viscosity and lower arterial compliance in resistance-trained men.
doi.org/10.14814/phy...
#Cardiovascular #Exercise #Cardiac #Physiology
doi.org/10.14814/phy...
#Cardiovascular #Exercise #Cardiac #Physiology
#Exercise #oxygen pathway analysis comparing patients with #longCOVID, or chronic #fatigue #syndrome/#myalgic #encephalitis, vs. healthy subjects, reports impaired skeletal #muscle oxygen diffusion as a shared mechanism of exercise intolerance
doi.org/10.14814/phy...
doi.org/10.14814/phy...
September 8, 2025 at 9:15 AM
#Exercise #oxygen pathway analysis comparing patients with #longCOVID, or chronic #fatigue #syndrome/#myalgic #encephalitis, vs. healthy subjects, reports impaired skeletal #muscle oxygen diffusion as a shared mechanism of exercise intolerance
doi.org/10.14814/phy...
doi.org/10.14814/phy...
Announcing appointment of Dr. Blair D. Johnson, Indiana University School of Public Health-Bloomington, USA, as a new Associate Editor at PhysReports! Blair brings expertise in #autonomic, #environmental, #cardiovascular and #respiratory #physiology
@physoc.bsky.social
@apspublications.bsky.social
@physoc.bsky.social
@apspublications.bsky.social
September 4, 2025 at 9:15 AM
Announcing appointment of Dr. Blair D. Johnson, Indiana University School of Public Health-Bloomington, USA, as a new Associate Editor at PhysReports! Blair brings expertise in #autonomic, #environmental, #cardiovascular and #respiratory #physiology
@physoc.bsky.social
@apspublications.bsky.social
@physoc.bsky.social
@apspublications.bsky.social
#ECG analysis on brown bears documents prolonged #ventricular repolarization independent of #heartrate in #hibernation vs. activity, implicating protective adaptations that prevent #hypothermia induced ventricular #arrhythmias.
doi.org/10.14814/phy...
#Cardiovascular #ComparativePhysiology
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#Cardiovascular #ComparativePhysiology
September 1, 2025 at 9:15 AM
#ECG analysis on brown bears documents prolonged #ventricular repolarization independent of #heartrate in #hibernation vs. activity, implicating protective adaptations that prevent #hypothermia induced ventricular #arrhythmias.
doi.org/10.14814/phy...
#Cardiovascular #ComparativePhysiology
doi.org/10.14814/phy...
#Cardiovascular #ComparativePhysiology