Silvia Piconese
@pikolab.bsky.social
Small (Pico) Lab based in Sapienza University of Rome. In love with regulatory T cells
#Treg #immunology
#Treg #immunology
Tregs can choose between producing TNF or sensing TNFR2... and the two states are much different!
See our latest story published in @eurjimmunol.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
See our latest story published in @eurjimmunol.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation
Tregs exist in two functional states: TNF-producing Tregs, which are expanded in mouse models of chronic inflammation and cancer, and TNFR2-expressing Tregs, which dominate and transmit their phenoty...
onlinelibrary.wiley.com
September 23, 2025 at 12:29 PM
Tregs can choose between producing TNF or sensing TNFR2... and the two states are much different!
See our latest story published in @eurjimmunol.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
See our latest story published in @eurjimmunol.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Our study "Iron capture through CD71 drives perinatal and tumor-associated Treg expansion" is available at @jci-insight.bsky.social
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
March 30, 2025 at 9:27 AM
Our study "Iron capture through CD71 drives perinatal and tumor-associated Treg expansion" is available at @jci-insight.bsky.social
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...