Physics of Life Leuven
@pol-kuleuven.bsky.social
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The KU Leuven Physics of Life cluster (PoL@KUL) organizes research initiatives aimed at studying the behavior of biological systems from a Physics perspective. https://fys.kuleuven.be/zmb/PoLatKUL https://www.kuleuven.be/english #softmatter #biophysics
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Working on biosensors? Don’t miss this MDPI webinar introducing thermal biosensing via the heat-transfer method (HTM) — a simple yet powerful way to detect biomolecular interactions and monitor cells.
Pioneers of HTM will share their insights!
#Biosensors #HTM
More info: sciforum.net/event/Sensor...
pol-kuleuven.bsky.social
🧪 Catarina Fernandes presented her work on fully bioresorbable electrochemical sensors — optimizing Mo+MoOx electrodes for long-term stability in biofluids. A promising platform for transient, in situ biomarker monitoring. #transientsensors #biosensors
pol-kuleuven.bsky.social
🔬 Momina Amir showcased an elegant approach to fabricating high-aspect-ratio silicon microneedles — combining sharpness with substrate flexibility. A key step forward for wearable biosensors & minimally invasive healthcare. #microneedles #biomedicalengineering
pol-kuleuven.bsky.social
👏 Congratulations to Jolan Wellens for presenting cutting-edge research on monitoring intracochlear inflammation using electrochemical sensing with cochlear implants — advancing real-time trauma detection during implantation. #neurotech #biosensors2025
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🌱 Our young researchers made us so proud at #Biosensors2025 in Lisbon! Representing KU Leuven and #PhysicsOfLife with scientific excellence and innovation on the international stage. #KULeuven #researchimpact #biosensors
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🧬 Next week we’re thrilled to host Prof. Nick Gilbert (U. of Edinburgh) for a deep dive into the Structure & Dynamics of active chromatin!
🎙️ “Irregular nucleosome positioning modulates 3D structure and dynamics of active chromatin”

#Chromatin #Biophysics #GeneRegulation
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In this work, COMSOL simulations and experiments supported the design of our next-gen biosensor—coming soon!
pol-kuleuven.bsky.social
New paper out from Patrick Wagner Group! We tested a prototype HTM (heat transfer method) device to assess antimicrobial efficacy.

#Biophysics #HTM #Biosensors #Antimicrobials #COMSOL #DrugScreening

More information here: www.mdpi.com/1424-8220/25...
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Using screen-printed electrodes + molecularly imprinted polymers, our sensor hits a 19 pM detection limit and works in both tap and river water. No lab needed. Just dip & detect.
A step toward faster, accessible environmental monitoring. 🌍🧪
pol-kuleuven.bsky.social
🚨 New paper out from Patrick Wagner Group! We developed a low-cost, portable electrochemical sensor for detecting PFOA — one of the most persistent PFAS pollutants — on-site and down to very low levels.

#PFAS #Sensors #WaterQuality #MIPs #EnviroTech

pubs.acs.org/doi/full/10....
Tracking Perfluorooctanoic Acid in Tap and River Water Employing Screen-Printed Electrodes Modified with Molecularly Imprinted Polymers
While existing polyfluoroalkyl substances (PFAS) detection techniques are highly sensitive, their broader implementation is limited by the need for expensive equipment, lengthy analysis times, and specialized personnel. This underscores the need for fast, reliable, cost-effective, and accessible PFAS detection methods to avoid exposure to these pollutants and expedite the remediation of contaminated environments. Currently, portable electrochemical sensors for in situ contaminant detection are gaining significant attention. This study focuses on developing an electrochemical sensor for on-site perfluorooctanoic acid (PFOA) detection utilizing screen-printed electrodes (SPEs) modified with molecularly imprinted polymers (MIPs). The sensor’s performance is evaluated using electrochemical impedance spectroscopy (EIS), with the electrochemical signals for PFOA detection arising from the specific interactions between MIPs and PFOA. The sensor exhibits a linear response to PFOA in phosphate-buffered saline within a concentration range of 0.1 nM to 10 μM, a detection limit of 19 ± 1 pM, and a quantification limit of 42 ± 3 nM. The selectivity of the sensor is assessed by measuring its response to four different PFAS compounds. Additionally, its real-world applicability is tested by analyzing the EIS response in tap and river water samples. The developed sensor, which combines an easy-to-use dipstick format with readily prepared SPEs, has the potential for large-scale production for in situ PFOA detection.
pubs.acs.org
pol-kuleuven.bsky.social
We’ve been working on integrating real-time H₂O₂ sensing into cochlear implants to detect trauma as it happens during surgery. Monitoring intracochlear peroxide levels is a step toward smarter and safer hearing implants.

Huge thanks to the amazing multidisciplinary team behind this work!
pol-kuleuven.bsky.social
Exciting news! PoL@KUL invites you to the inaugural lecture of the International Francqui Professor 2024-25, Prof. Davide Marenduzzo (U. of Edinburgh) on Tuesday, April 29, 2025 in Leuven:

Biophysical principles of chromosome organisation

Info and registration:

fys.kuleuven.be/english/coll...
pol-kuleuven.bsky.social
PoL Jobs! Prof. Thomas Cocolios is offering 2 fully-funded PhD positions to work between KU Leuven and JRC Karlsruhe on improving the supply of alpha-emitting medical radionuclides for research:
www.kuleuven.be/personeel/jo...
2 Joint PhD positions with JRC Karlsruhe for medical radionuclide production
Research at a top European nuclear facility for tomorrow's cancer treatments
www.kuleuven.be
pol-kuleuven.bsky.social
Tomorrow 05/03/2025, Prof. Takahiro Sakaue from Aoyama-Gakuin University, Tokyo will share with us his recent findings on chromatin dynamics in C. Elegans Embryos !
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From colorful phase transitions to real-world applications, it was exciting to see their enthusiasm for science in action. Hope to inspire the next generation of researchers! #STEM #LiquidCrystals #ScienceOutreach
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Yesterday, we had the pleasure of hosting a group of students from Sint-Pieterscollege sintpieterscollege.be! After a presentation on biosensors, they got a hands-on look at liquid crystals.
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Prof. Krause is organizing this year the 16th Workshop on the Engineering of Functional Interfaces, taking place at Queen Mary University of London on 7th and 8th July 2025.
www.sems.qmul.ac.uk/events/enfi2...
Abstract submission closes on the 30th of April 2025, see you in London!
pol-kuleuven.bsky.social
First post since our migration to Bluesky! Yesterday we had the pleasure to receive Prof. Steffi Krause from Queen Mary University of London.
www.sems.qmul.ac.uk/research/gro...
Prof. Krause gave an exciting talk on Photoelectrical imaging for live cell monitoring and sensor applications.