Pramod Shinde
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pramodsshinde.bsky.social
Pramod Shinde
@pramodsshinde.bsky.social
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Computational Biologist @ La Jolla Institute for Immunology
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Reposted by Pramod Shinde
lji.org
New Bordetella pertussis research from LJI Prof. Bjoern Peters, LJI Prof. Alessandro Sette, and colleagues:

pubmed.ncbi.nlm.nih.gov/40169665/

#Pertussis #WhoopingCough #VaccineResearch #InfectiousDisease #Immunology #ImmuneSystem
Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop - PubMed
Outbreaks of Bordetella pertussis (BP), the causative agent of whooping cough, continue despite broad vaccination coverage and have been increasing since vaccination switched from whole-BP (wP) to ace...
pubmed.ncbi.nlm.nih.gov
April 2, 2025 at 4:51 PM
Reposted by Pramod Shinde
hipcproject.bsky.social
Our collaborator Matthew Altman explains to today's mtg the #immune #signatures project aimed at mapping markers for healthy or unhealthy immune systems.

Others on project include @pramodsshinde.bsky.social
Fergal Duffy Amnah Siddiqa Chian He and Jian Xing.
More info at immunspace.org
Slide from talk by Matthew Altman at mtg today of Human Immunology Project Consortium. Slide shows names of team members: Fergal Duffy, Pramod Shinde, Amnah Siddiqa, Chuan He and Jian Xing.
April 2, 2025 at 5:23 PM
Reposted by Pramod Shinde
danielhoffmann1.bsky.social
Competitve modelling has a long tradition in biology. Here ~50 contestants predicted effects of a whooping cough booster #vaccination. Comparison with actually measured effects identifies best methods. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012927
Putting computational models of immunity to the test—An invited challenge to predict B.pertussis vaccination responses | PLOS Computational Biology
journals.plos.org
April 1, 2025 at 6:39 AM