Amanda Randles 🧪⚛️ 👩‍🔬
@profamandarandles.bsky.social
3.5K followers 8.1K following 140 posts
Director of the Duke University Center for Computational and Digital Health Innovation. Alfred Winborne Mordecai and Victoria Stover Mordecai Associate Professor of Biomedical Engineering. Research in HPC and digital twins for health.
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profamandarandles.bsky.social
It’s #BMES2025! The Randles Lab is sharing new work on digital twins for heart failure, HRV-based model reduction, cellular heterogeneity, and APR modeling of RBC–cancer interactions. Stop by the Duke booth to learn about our Center for Computational and Digital Health Innovation! #DigitalHealth
profamandarandles.bsky.social
Thanks for having me! Had such a great time discussing HPC in Health with this community.
profamandarandles.bsky.social
Join us Wed, Oct 2 @ 3 PM ET for the Center for Computational and Digital Health Innovation + Duke Quantitative Biodesign Virtual Seminar! Fabian Theis (Helmholtz Munich/TUM) will speak on “Decoding cellular systems.” All welcome. Register: duke.qualtrics.com/jfe/form/SV_...
profamandarandles.bsky.social
🧪Our new work in AJNR: Photon-counting CT + iMAR offers clear, non-invasive imaging of coiled intracranial aneurysms—showing promise as an alternative to invasive angiography.

Collab led by Brian Mac Grory with David Urick, Fides Schwartz, David Hasan & Evan Calabrese
🔗 www.ajnr.org/content/earl...
Photon-Counting Computed Tomography for Evaluation of Coiled Intracranial Aneurysms
BACKGROUND AND PURPOSE: Intracranial aneurysms treated with endovascular embolization often require surveillance imaging using digital subtraction angiography, an invasive, risky, and expensive proced...
www.ajnr.org
profamandarandles.bsky.social
Full circle. From my first HLF as a student in 2013 ➡️ to giving a talk on stage as a laureate this year. Grateful for the journey and the community that made it possible. #HLF2025
profamandarandles.bsky.social
Yesterday our Center hosted the first Espresso Chat ☕ with Jeff Hammond! He shared his path from quantum chemistry to #HPC and reminded students to lean into strengths, keep learning, and stay ahead of the curve. Favorite moment: a Valentine that read “Jeff the Scientist.” #CareerJourney
profamandarandles.bsky.social
We’re excited to welcome Leah Howell to the Randles Lab as a new graduate student in Biomedical Engineering!

Looking forward to all the discoveries ahead—welcome to the team, Leah!

#RandlesLab #bme #dukebme #dukeuniversity
profamandarandles.bsky.social
🧪👩‍🔬Congrats to Wendy Wu on advancing to PhD Candidacy in Biomedical Engineering! Her work on computational models of cellular mechanics is pushing forward digital health innovation. Proud PI moment (yes, I was the one taking pics mid-exam). #WomenInSTEM #PhDCandidate
profamandarandles.bsky.social
Excited to be speaking at the @WichitaState BME Seminar this Friday (Sept 5)!

📢 Talk: Developing and Applying Vascular Digital Twins
🕑 2:00–3:15 PM CT

Exploring HPC + wearables for real-time cardiovascular health. #DigitalTwins #HPC #BME
profamandarandles.bsky.social
🧪 #CompHealth Corner: High-channel neural interfaces are here—but routing dense pad grids is a major hurdle. This new paper from #CCDHI member Jonathan Viventi introduces an efficient, automated algorithm to optimize trace paths and layer count in thin-film devices. #Neuroengineering #HCI
profamandarandles.bsky.social
Wow, thanks so much for the support and sharing! I’m really excited about the new initiative.
profamandarandles.bsky.social
Launching Fall 2025: Duke’s Computational & Digital Health Certificate 🎓 Training future leaders at the intersection of AI, modeling, wearables & ethics. Learn more: duke.is/certificate #DigitalHealth #AI @dukeengineering.bsky.social
profamandarandles.bsky.social
New in npj Digital Medicine: Our proof-of-concept digital twins predict pulmonary pressures noninvasively, offering a path to earlier detection & better care for right heart failure. duke.is/hf
profamandarandles.bsky.social
“Great teams embrace the fact that the strength of the team is the team.”–Coach K
At the Duke Center for Computational and Digital Health Innovation, collaboration drives impact. We’re excited to welcome our new Associate Directors, who will strengthen our research and education missions.
duke.is/ad
Center Names Associate Directors  - Center for Computational and Digital Health Innovation
The Duke Center for Computational and Digital Health Innovation welcomes our new Associate Directors to its leadership team. The Associate Directors will help expand and strengthen our research and ed...
comphealth.duke.edu
profamandarandles.bsky.social
CompHealth Corner: What Are We Reading?
📘 Paper from Center researcher Jonathan Viventi in the Journal of Neural Engineering: a deepest-exit-first algorithm for routing dense pad grids in thin-film neural interfaces—solving a key bottleneck in scaling next-gen implants.
#Neurotech #AI 🧪
profamandarandles.bsky.social
Fun new wall art from LLNL :) still figuring out where to put it but it’s pretty cool. (And yes those are part of my #SC jacket collection below. We all have SC clothes in our offices right?) #hpc #scivis #artofhpc
profamandarandles.bsky.social
🧪 When doctors track heart disease, they need scans over time—but aligning them is tough, tedious, and subjective. We built an algorithm that automates alignment, saving time and effort.

Read more 👉 duke.is/align24

@dukeengineering.bsky.social #research #comphealth #CCDHI #cardiovascular
profamandarandles.bsky.social
CompHealthCorner: HPC powers today’s AI, science, and innovation—but U.S. leadership is at risk. This Science article urges a bold, whole-nation roadmap to secure the future of high-performance computing. A must-read for anyone in tech policy. #CompHealthCorner #HPC #AI #SciencePolicy
profamandarandles.bsky.social
Dr. John Hickey, our co-Associate Director of AI, is pioneering AI-empowered systems biology to advance spatial cell therapies. His award-winning work marries engineering, immunology & computation to shape the future of personalized medicine.
Read more: comphealth.duke.edu/featured-res...
profamandarandles.bsky.social
Added some new personal touches to the office to kick off the new year :) as part of my sabbatical this year, we took the kids to Australia (yes I questioned the long flight too :)) and I thought I would add some pics to my office. Do you have family artwork or custom mousepads in your office?
profamandarandles.bsky.social
How can AI in healthcare reduce bias instead of reinforcing it? This week’s #CompHealthCorner spotlights a new Nursing Outlook article by Ben Goldstein and colleagues on HUMAINE—a team‑developed curriculum to equip nurse scientists in AI, bias mitigation, and equity.
profamandarandles.bsky.social
🧪Oops—July’s #CompHealthCorner is a few days late (I was traveling)! Catch up on key papers in ML-driven MD, RAG in medicine, open-source ANS tools, and award-winning cancer simulations. Don’t miss these breakthroughs! 👉 comphealth.duke.edu/comphealth-c... #DigitalHealth #AI #Bioengineering
profamandarandles.bsky.social
Great article by @dukeengineering.bsky.social Center for Computational and Digital Health Innovation member @boyuan-chen.bsky.social.
profamandarandles.bsky.social
🧪As the nursing shortage grows, robotics powered by physical AI may help extend care. This #CCDHI article shows how nurses can lead in designing ethical, human-centered robotic systems to support—not replace—care. A must-read for future-ready healthcare. #CompHealthCorner #AIinNursing