As a Guest Editor for JoVE, I am organizing a Topical Collection titled “Techniques for the Control of Immune Cell Function Using Physical Forces.” Interested in contributing? Please submit an abstract here:
app.jove.com/methods-coll...

Some good news: Prolactin sensitizes HT29 cells to TRAIL-mediated apoptosis. We tested the efficacy of our next generation dual affinity liposomes, based on immune cell delivery! #nanomedicine

We built a computational model of the JAK2/STAT3 signaling pathway in response to late-pregnancy PRL levels!
Freely available at:
doi.org/10.5281/zeno...

Cancer stem-associated markers and EMT increase with prolactin treatments.

We found that pregnancy prolactin levels cause biphasic STAT3 phosphorylation and increased JAG1 and NICD expression.

Pregnant colorectal cancer patients have larger tumors yet fewer options exist for anticancer interventions compared to non-pregnant colorectal cancer patients.

Before we get into the science, this was my first opportunity to publish a second, “native language” abstract with the paper… so we were able to include a Spanish language version in lead author @MariaLCavestany ‘s mother tongue, muy bien! 🇪🇸

¿Qué pasa? 🚨new paper alert!🚨
I am excited to share our new paper, an important collaboration with Dr. Cathy Eng and VUMC:
Increased prolactin levels in pregnancy affect colorectal cancer aggressiveness
#OpenAccess 🧵👇
link.springer.com/article/10.1...

It’s finally BMES week! The King Lab is giving 6 oral and 12 poster presentations, with a delegation that includes high school student, undergrad, PhD students, postdocs, research professor and… moi! Check out our work, and also visit the Rice BIOE booth and reception!

🚨 NEW PAPER ALERT! 🚨
Our new review on “Cellular mechanoactivation of antigen-presenting cells and T cells for cancer immunotherapy” in Current Opinion in Biomedical Engineering! Free #OpenAccess download for all readers! #immunoengineering #mechanobiology

www.sciencedirect.com/science/arti...

Amazing! Friend and fellow mechanobiologist Nadeen Chahine was in San Diego and caught a Padres game… and it was Michael King bobblehead night! Thank you so much Nadeen, this is going to look great in my office! 👑⚾️

I'm pleased to share this nicely done video that captures how special the Rice partnership with the Texas Medical Center is for biomedical researchers... 🔬 🧪 🏙️

Join us at the "Health Innovations in the Rice-TMC Ecosystem" symposium for a series of presentations on Innovations in Cancer Research
April 24-25
Helix Park's TMC3 Collaborative Building
Tickets: bit.ly/3DaBGrR About the event: bit.ly/4kcZP1I

Congratulations to King Lab PhD student Natalie Curry, who won a poster prize at the NCI Tissue Engineering Collaborative Annual Investigators Meeting, for her study on the effect of fluid shear stress on macrophage polarization! Outdoor session in Miami, fun! 🔬☀️

Late to the party… start me up, my Bleeps!