qgouil.bsky.social
Quentin Gouil
@qgouil.bsky.social
79 followers 94 following 4 posts
Lab head at the Olivia Newton-John Cancer Research Institute, Australia. Health and Epigenomics Across Life (HEAL)
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qgouil.bsky.social
Quentin Gouil @qgouil.bsky.social · 13d
🚴‍♂️ I’m riding to make a difference: help me support cancer research 🎗️
I’m training for a ride and raising funds for cancer research, support and prevention.
You can contribute via my fundraising page here:
👉 vicdiscovery.tourdecure.com.au/quentin-gouil Thank you for your support!
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Make a donation today to support VIC Discovery Tour 2025
vicdiscovery.tourdecure.com.au
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qgouil.bsky.social
Quentin Gouil @qgouil.bsky.social · 22d
Long-read transcriptomics is advancing quickly, we benchmarked leading bulk and single-cell protocols in this awesome collaborative effort!
We hope it will be a valuable resource for the community.
Congrats @youyupei.bsky.social @mritchieau.bsky.social @michaelbclark.bsky.social and all!
youyupei.bsky.social
Yupei You @youyupei.bsky.social · 23d
Excited to share our latest preprint: LongBench—a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches.
www.biorxiv.org/content/10.1...
Benchmarking long-read RNA-sequencing technologies with LongBench: a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches
Long-read RNA sequencing enables full-length transcript profiling and improved isoform resolution, but variable platforms and evolving chemistries demand careful benchmarking for reliable application....
www.biorxiv.org
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Reposted by Quentin Gouil
long-read-tools.bsky.social
long-read-tools.bsky.social @long-read-tools.bsky.social · Aug 29
>1,000 long-read tools in the latest update! 🚀
Long-read trancriptomics heating up 🔥
long-read-tools.org
long-read-tools
A catalogue of long read analysis tools
long-read-tools.org
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Reposted by Quentin Gouil
wehi-research.bsky.social
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · Aug 5
Discovery: mRNA vaccine candidate blocks malaria from reproducing inside mosquitoes, cuts transmission by up to 99.7%. Built on cryo-EM insights into parasite’s fertilisation machinery. A key step towards elimination. In @science.org

🔗 www.wehi.edu.au/news/reveale...
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Reposted by Quentin Gouil
thamlab.bsky.social
Wai-Hong Tham @thamlab.bsky.social · Aug 1
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗

🦟 Transgenic parasites without Pfs230 D13D14 do not transmit

🦙 💉Nanobodies + mRNA induced antibodies reduce transmission

New in @Science.org

www.science.org/doi/10.1126/...

#ScienceResearch #Malaria #WEHI
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Reposted by Quentin Gouil
mig-unimelb.bsky.social
MIG @mig-unimelb.bsky.social · Feb 18
🚨 We're hiring! 🚨

The School of Mathematics & Statistics, UniMelb seeks a scientist in Machine Learning in Omics to lead research in statistical methods for omics.

📍 MIG | 📅 By Apr 11

🔗 jobs.unimelb.edu.au/en/job/91945...

#MachineLearning #Omics #DataScience #HigherEd #Mathematics #Statistics
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Reposted by Quentin Gouil
thamlab.bsky.social
Wai-Hong Tham @thamlab.bsky.social · Feb 17
Interested in #malaria transmission and fertilisation? Check out our new work using cryo-EM of ENDOGENOUS sexual stage parasites to determine the Pfs230-Pfs48/45 fertilisation complex - please read & share!

structures| nanobodies |human immune responses | mRNA-LNP

www.biorxiv.org/content/10.1...
www.biorxiv.org
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Reposted by Quentin Gouil
wkhuber.bsky.social
Wolfgang Huber @wkhuber.bsky.social · Feb 14
Do you love software engineering for exciting biological applications, open science,open source, R, Bioconductor, modern web, cloud& ML technologies?

We're looking for a software engineer to work on R/Bioconductor tools for biological data science and AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Picture of the conference centre on the EMBL campus in Heidelberg
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Reposted by Quentin Gouil
nadia-davidson.bsky.social
Nadia Davidson @nadia-davidson.bsky.social · Feb 10
Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf.bsky.social. Thnx to all contributors incl. @qgouil.bsky.social for the pea data!
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qgouil.bsky.social
Quentin Gouil @qgouil.bsky.social · Feb 10
This blew my mind youtu.be/Xe-83tBcxhs
The double Holliday junction comes to life!
Gorgeous work from @drewberry.bsky.social and team.
DNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tv
YouTube video by WEHImovies
youtu.be
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qgouil.bsky.social
Quentin Gouil @qgouil.bsky.social · Feb 10
No genome, no problem!
Check out @nadia-davidson.bsky.social and Alex Yan’s benchmark of reference-free Diff Expr. Helping us out with our 🌱 transcriptomes!
www.biorxiv.org/content/10.1...
Towards accurate, reference-free differential expression: A comprehensive evaluation of long-read de novo transcriptome assembly
Long-read RNA sequencing has significantly advanced transcriptomics by enabling the full length of transcripts to be assessed. However, current analysis methods often depend on a high-quality referenc...
www.biorxiv.org
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