Qianxuan(Sean) She
qianxuan.bsky.social
Qianxuan(Sean) She
@qianxuan.bsky.social
PhD candidate in the microbialARC at Children's Hospital of Philadelphia
Over 3 years we performed WGS-based surveillance of S. aureus in the NICU at @childrensphila.bsky.social, sequencing both surveillance and bloodstream infection isolates, to understand how colonization, transmission, and persistence are associated with invasive infection in high-risk neonates.
Rapid dissemination of Staphylococcus aureus in the neonatal intensive care unit is associated with invasive infection - Nature Communications
In this work, authors use whole genome tracking in a neonatal intensive care unit to reveal a strong link between Staphylococcus aureus colonization and invasive infection, pinpointing critical new ta...
www.nature.com
February 10, 2026 at 5:55 PM
Reposted by Qianxuan(Sean) She
Thrilled to share this study tracking Staph aureus carriage and transmission across the NICU using genomics! Work done w @pjplanet.bsky.social & @ahmedmicrobes.bsky.social and made possible by @centermicrobialmed.bsky.social.

Study co-led by the amazing @qianxuan.bsky.social & Lakshmi Srinivasan!
Rapid dissemination of Staphylococcus aureus in the neonatal intensive care unit is associated with invasive infection - Nature Communications
In this work, authors use whole genome tracking in a neonatal intensive care unit to reveal a strong link between Staphylococcus aureus colonization and invasive infection, pinpointing critical new ta...
www.nature.com
February 10, 2026 at 1:41 PM
Reposted by Qianxuan(Sean) She
This study was made possible through an amazing collaboration across the CHOP NICU, CHOP Infectious Disease Diagnostics Lab (IDDL), CHOP Infection Prevention and Control, the Microbial Archive and Cryocollection at CHOP (MicrobialARC), and @centermicrobialmed.bsky.social.
March 1, 2025 at 1:21 PM
Reposted by Qianxuan(Sean) She
In this study we tracked carriage, transmission, and invasive infection with S. aureus across 33 months in the NICU. Using longitudinal WGS, we identify risk factors for transmission of invasive clones, and show strains that are transmitted more rapidly are more likely to cause invasive disease
March 1, 2025 at 1:21 PM
Reposted by Qianxuan(Sean) She
Excited to share our work with @pjplanet.bsky.social and @ahmedmicrobes.bsky.social tracking Staph aureus transmission across the NICU using genomics!!

This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit (N...
www.medrxiv.org
March 1, 2025 at 1:21 PM
Reposted by Qianxuan(Sean) She
Our preprint on genomic epidemiology in the NICU! Strains that transmit faster also cause more invasive disease! nam10.safelinks.protection.outlook.com?url=https%3A...
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background : Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit ...
nam10.safelinks.protection.outlook.com
February 28, 2025 at 2:00 PM