Prof Richard Buggs
@rbuggs.bsky.social
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rbuggs.bsky.social
New review in Biophysical Journal shows that the ubiquitous molecular machine ATP synthase is highly efficient, and needs to be so to support life. This level of efficiency makes all currently suggested evolutionary pathways for ATP synthase evolution implausible. sciencedirect.com/science/arti... 🧪
The molecular mechanism of ATP synthase constrains the evolutionary landscape of chemiosmosis
ATP synthase, the enzyme responsible for regenerating adenosine triphosphate (ATP) in the cell, comprises a proton-translocating motor in the cell mem…
sciencedirect.com
Reposted by Prof Richard Buggs
danielwood1992.bsky.social
Check out our preprint presenting the construction and application of a pangenome for European ash @laura-j-kelly.bsky.social @rbuggs.bsky.social
biorxiv-genomic.bsky.social
European ash pangenome reveals widespread structural variation and a diverse genetic basis for low ash dieback susceptibility https://www.biorxiv.org/content/10.1101/2025.07.16.665114v1
rbuggs.bsky.social
Our latest preprint: Genetic basis of traits and local adaptation in UK silver birch 🧪
www.biorxiv.org/content/10.1...
Genetic basis of traits and local adaptation in UK silver birch
Knowledge of the genomic basis of phenotypes in forest trees lags that of other economically important organisms. We sequenced the genomes of 2054 silver birch trees from 20-year-old field trials at three locations in Britain, each site containing trees from the same 29 source populations. Our results lay foundations for genomic source-selection and breeding. We discovered single nucleotide polymorphisms (SNP) associated with tree height, wood density, carbon isotope composition and stem form. Using genome-wide SNP we predicted variation in several phenotypic traits of trees with a similar genetic background and estimated the breeding values of 148 selected plus trees. We identified loci associated with adaptation to source local environments. We used these loci to forecast adaptation to each trial site and future predicted conditions at source. Comparison of these forecasts to phenotypic performance in the trials suggests that genomic forecasts of adaptation to future climates should be interpreted with caution. ### Competing Interest Statement The authors have declared no competing interest. Department for Environment Food and Rural Affairs, https://ror.org/00tnppw48, Center for Forest Protection Grant 2202 Research Council of Finland, 343059
www.biorxiv.org
rbuggs.bsky.social
Thanks Kew!
The paper itself can be found here: www.science.org/doi/10.1126/...
rbgkew.bsky.social
BIG NEWS! We’ve found that ash trees are fighting back against ash dieback disease! 🌳💪

Scientists at Kew & QMUL ‪@qmul.bsky.social have discovered that young ash trees are evolving resistance to this devastating fungus - & fast 🌍

Read the story👉 www.kew.org/read-and-wat...

#PlantScience #SciNews
rbuggs.bsky.social
If you don't have a Science subscription, a free full text link can be found on this page: richardbuggs.com/publications/
Publications – Richard Buggs
richardbuggs.com
rbuggs.bsky.social
If you don't have a Science subscription, a free full text link can be found on this page: richardbuggs.com/publications/
Publications – Richard Buggs
richardbuggs.com
Reposted by Prof Richard Buggs
rbgkew.bsky.social
BIG NEWS! We’ve found that ash trees are fighting back against ash dieback disease! 🌳💪

Scientists at Kew & QMUL ‪@qmul.bsky.social have discovered that young ash trees are evolving resistance to this devastating fungus - & fast 🌍

Read the story👉 www.kew.org/read-and-wat...

#PlantScience #SciNews