Das Lab
@rdaslab.bsky.social
46 followers 11 following 1 posts
Our lab seeks an agile and predictive understanding of how RNAs structurally code for information processing and replication in living systems.
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rdaslab.bsky.social
The results are in: top codes in Stanford #RNA 3D Folding @kaggle.com competition are competitive with CASP16-leading humans Vfold, beat AlphaFold 3. Top team’s trick was template-based modeling, not #DeepLearning. Congrats: john, odat, Eigen, + all 1706 participants! www.kaggle.com/competitions...
Reposted by Das Lab
eternagame.org
Meet @frameshifter.org, the new nonprofit program established to steward Eterna's future and advance public engagement in scientific research through games, collective and hybrid intelligence, and human centered design.
frameshifter.org
Introducing: Frameshifter, a new nonprofit program (fiscally sponsored by @superbloom.design ) accelerating discoveries and inclusion in science through public engagement in research.
Reposted by Das Lab
rnajournal.bsky.social
Community science presents an alternative discovery framework for precision ASO drugs. A community voting system facilitates the testing of top designs, followed by experimentation to evaluate and score how well player-designed drugs ameliorated molecular disease phenotypes bit.ly/44u5oTv
Reposted by Das Lab
kellythd-nguyen.bsky.social
Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.
mrclmb.bsky.social
Sebastian Balch, Zala Sekne & Elsa Franco-Echevarría in @kellythd-nguyen.bsky.social's group have confirmed the existence of dimeric telomerase and illustrated how it is key to telomere maintenance:
www2.mrc-lmb.cam.ac.uk/first-struct...

#LMBResearch @yiliangding.bsky.social @rdaslab.bsky.social 🧪
Structure of telomerase dimer with key catalytic codes and H/ACA RNPs highlighted with schematic illustrating how dimer disruption leads to shortened telomeres and disease mutations of the dimers causes premature ageing diseases