reneechang.bsky.social
Renee Chang
@reneechang.bsky.social
27 followers 17 following 1 posts
PhD Candidate in the Kranzusch Lab at Harvard Medical School / studying mechanisms of viral immune evasion
Posts Media Videos Starter Packs
Reposted by Renee Chang
kranzuschlab.bsky.social
Kranzusch Lab @kranzuschlab.bsky.social · Aug 22
The beautiful, ever-expanding universe of viral proteins targeting nucleotide immune signals!

Paper by @reneechang.bsky.social in @cp-molcell.bsky.social on a nucleotide sponge www.cell.com/molecular-ce...

and preprint by @doudna-lab.bsky.social on viral nucleases www.biorxiv.org/content/10.1...
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense
Chang et al. discover anti-CBASS 4 (Acb4), a family of viral sponges that inhibits bacterial immunity by sequestering nucleotide immune signals. Acb4 homologs in phages that infect hosts across all ma...
www.cell.com
19 48
reneechang.bsky.social
Renee Chang @reneechang.bsky.social · Aug 23
Excited to share my PhD work in the @kranzuschlab.bsky.social, out now in Molecular Cell @cp-molcell.bsky.social

We discover Acb4, a new family of viral sponges that sequesters nucleotide immune signals and defines molecular features that enable ligand specificity.

www.cell.com/molecular-ce...
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense
Chang et al. discover anti-CBASS 4 (Acb4), a family of viral sponges that inhibits bacterial immunity by sequestering nucleotide immune signals. Acb4 homologs in phages that infect hosts across all ma...
www.cell.com
1 9 29