#RaFJC Day 4 - RPL = ≥2 miscarriages, affecting 1–2% of couples. Half remain unexplained, often immune‑related.

#RaFJC #Pregnancyloss #IVF #Miscarriage #immuneresponse #inflammatoryresponse

#RaFJC Day 3💚

Pregnancy is an immune balancing act: tolerance of the fetus + defense against pathogens.

𝗗𝗮𝘆 𝟮 𝗼𝗳 #RaFJC - 𝗜𝗺𝗺𝘂𝗻𝗲 𝗔𝗱𝗮𝗽𝘁𝗮𝘁𝗶𝗼𝗻 𝗳𝗿𝗼𝗺 𝗖𝗼𝗻𝗰𝗲𝗽𝘁𝗶𝗼𝗻 𝘁𝗼 𝗣𝗿𝗲𝗴𝗻𝗮𝗻𝗰𝘆 🟢

Implantation requires a delicate immune balance. Enough inflammation to remodel the uterus, but enough tolerance to accept the embryo. Cytokines, NK cells, and macrophages shape embryo acceptance

#Implantation #Fertility

👱‍♀️POI affects 1–3% of women <40; most cases are unexplained.

We’re excited to announce the launch of our new & improved Journal Club!

Hosted on all RAF social platforms, this week-long event will feature discussions on 3 articles, covering the journey from ovulation to conception & implantation, through pregnancy & delivery, and clinical translation.

#RaFJC

New research by Riley E Thompson et al. presents a three-dimensional canine endometrial organoid model that responds to steroid hormones and offers a valuable in vitro system for studying cystic endometrial hyperplasia.

Read the full article here: doi.org/10.1530/RAF-...

We’re pleased to welcome two new Associate Editors to Reproduction and Fertility! 👏

🟢 Prof. Holly LaVoie (University of South Carolina School of Medicine) – Ovarian Biology
🟢 Dr. Rita Rahban (University of Geneva) – Male Reproductive Health

Welcome to RaF the team💚

New research by Asha Vijay et al. reviews evidence on the link between infertility treatments and stroke risk in women.

Read the full article here: doi.org/10.1530/RAF-...

Zinc is essential for ovarian health.

A new study by James M Hester and Francisco J Díaz shows that chelating transition metals with DTPA disrupts growth of preantral follicles in vitro, highlighting the importance of zinc for healthy follicle development.

🔗 Read more: doi.org/10.1530/RAF-...

Did you know Reproduction & Fertility is co-owned by both the Society for Endocrinology & the Society for Reproduction & Fertility?

Members of either society get 25% off APCs when publishing with us!

For more info visit: raf.bioscientifica.com/page/about-R...

📢 Call for submissions for our special collection on Fertility Care in LMICs 🌍

Help shape this vital discussion on access, awareness & affordable treatments. Deadline: 31 Dec 2025.

Submit ➡️ [email protected]

Reproduction and Fertility is seeking a new Associate Editor to join our Editorial Board in the field of ovarian biology.

This is an excellent opportunity to contribute to the growth and development of a Q1 journal.

📩 Interested applicants are invited to send their CV to [email protected]

🌿 Could Graptophyllum pictum (caricature plant) offer new hope for endometriosis treatment?

A new study by Perpetue Mbede Atsama et al. investigates its potential to support fertility while easing disease symptoms.

Read the full article here: doi.org/10.1530/RAF-...

How can fertility be preserved in endangered species?

Ana Glória Pereira et al. explore new ways to culture testicular tissue from prepubertal collared peccaries in vitro.

Read the full article here: doi.org/10.1530/RAF-25-0026

👶IVF is highly effective, but the superovulation stage can make it costly.

A new multicenter trial by Urmila Diwekar et al. shows the Opt-IVF tool can personalise dosing, reduce monitoring, and improve outcomes, including higher pregnancy rates.

🔗Read the full article here: doi.org/10.1530/RAF-...

📢Introducing the official Bluesky account for Reproduction and Fertility.

We publish research and reviews on basic, translational and clinical #reproduction and #fertility, across all animals, including humans.

Follow us for research highlights, journal news, and opportunities to get involved!