resgen.io
@resgen-io.bsky.social
25 followers 22 following 17 posts
Genome browser and data thingy
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resgen-io.bsky.social
Did you know oxbow powers resgen? We use it to load bam and bigwig tiles. Great library!
nvictus.bsky.social
I'm proud to announce the latest release of 🧬 #Oxbow 🏹, with new features to make NGS data analysis more powerful, efficient, and "composable".

Learn more at: oxbow.readthedocs.io
resgen-io.bsky.social
Small but satisfying update over the weekend to (mostly) sync the styling between the main page and docs page:
Comparison of the resgen.io home page and the similarly styled docs page
resgen-io.bsky.social
Pssst 🤫... you can also try this live with @genomeinabottle.bsky.social data here:

resgen.io/paper-data/Z...
resgen-io.bsky.social
New year, new home page! Trying to make it easier to get to recently viewed projects and views. Access via the "home" button on the top menu bar when logged in.

Also added a small news feed to highlight recent updates you may or may not have noticed.

Happy new year!!
A screenshot of the new resgen.io home page showing recent projects and recent views.
resgen-io.bsky.social
Forgot about BLAT. That may work. Thanks!
resgen-io.bsky.social
I guess BLAST does this but its indexes are pretty hefty.
resgen-io.bsky.social
I wonder what it would take to search for a single sequence that may vary from 100 - 10k nt in length across hundreds of vertebrate genomes in less than a second 🤔.

Surely the index needs to be loaded into memory. Minimap2 seems promising or an online version of BWA?
resgen-io.bsky.social
And of course, a live link for anybody wishing to try this out themselves:

resgen.io/l/?d=YrhQaXb...
Reservoir Genome Browser
resgen.io
resgen-io.bsky.social
Pileup support is shaping up to be both performant and beautiful thanks to the Rust powered Oxbow package:

github.com/abdenlab/oxb...

Big shout out to @nvictus.bsky.social and @manzt.sh for implementing key features like buffering and file-like pointer support!
resgen-io.bsky.social
Not terribly mobile friendly either 🤔. Will have to work on that.
resgen-io.bsky.social
Got a version of paired-end read pileups out. The aesthetics are nice but the layout algorithm needs some work. Still not quite ready for prime time.

Nevertheless, here's a link to try it out with data from a Gorilla genome from Yoo et al. 2024 (Eichler lab).

resgen.io/paper-data/Y...
resgen-io.bsky.social
😍😍
golobor.bsky.social
A huge shout-out to @resgen-io.bsky.social !!! This online platform for browsing and sharing Hi-C and other kinds of genomic data was crucial for our lab from the beginning. Looking forward to new developments!!
resgen-io.bsky.social
Big update over the weekend: datasets can now be organized into folders!

Also, the default ordering for projects is by the last time they were opened. Soon to come is an option to select how they are ordered.
resgen-io.bsky.social
Less noticeable are back end updates to the UI framework. This brings it up to date and eliminates a large amount of technical debt.

Large changes invariable introduce some instability. Please excuse the inconvenience and reach out if you encounter any issues.
resgen-io.bsky.social
Also, some minor UI cleanups. Notably, the entire dataset can be dragged onto the browser to view.
resgen-io.bsky.social
Big update over the weekend: datasets can now be organized into folders!

Also, the default ordering for projects is by the last time they were opened. Soon to come is an option to select how they are ordered.
resgen-io.bsky.social
If this existed, one could mirror an entire directory tree in a resgen project, just like github.
resgen-io.bsky.social
Thinking of making the tilesets list support nesting, like a file browser 🤔. Tags and descriptions wouldn't change.