Rianne Prins
@rianneprins.bsky.social
Reposted by Rianne Prins
Can expression of a peptide lead to antimicrobial resistance? Yes it can!
We discovered this for a toxin we work with and started exploring how #peptides, #antimicrobialresistance and de-novo gene birth can come together.
@cp-trendsmicrobiol.bsky.social
Amazing work by @rianneprins.bsky.social
We discovered this for a toxin we work with and started exploring how #peptides, #antimicrobialresistance and de-novo gene birth can come together.
@cp-trendsmicrobiol.bsky.social
Amazing work by @rianneprins.bsky.social
Small proteins and peptides conferring protection against antimicrobial compounds
Small proteins and peptides conferring protection against antimicrobial compounds
The secretion of antimicrobials is widespread among microorganisms, many of which have developed protection mechanisms. While well-characterized protection mechanisms involve relatively large proteins – such as exporters or compound- or target-modifying…
dlvr.it
April 9, 2025 at 2:51 PM
Can expression of a peptide lead to antimicrobial resistance? Yes it can!
We discovered this for a toxin we work with and started exploring how #peptides, #antimicrobialresistance and de-novo gene birth can come together.
@cp-trendsmicrobiol.bsky.social
Amazing work by @rianneprins.bsky.social
We discovered this for a toxin we work with and started exploring how #peptides, #antimicrobialresistance and de-novo gene birth can come together.
@cp-trendsmicrobiol.bsky.social
Amazing work by @rianneprins.bsky.social
Reposted by Rianne Prins
Small proteins and peptides conferring protection against antimicrobial compounds
Small proteins and peptides conferring protection against antimicrobial compounds
The secretion of antimicrobials is widespread among microorganisms, many of which have developed protection mechanisms. While well-characterized protection mechanisms involve relatively large proteins – such as exporters or compound- or target-modifying…
dlvr.it
March 7, 2025 at 8:23 PM
Small proteins and peptides conferring protection against antimicrobial compounds
Now online: can small proteins and peptides play a role in antimicrobial resistance?
With @billerbecks.bsky.social we explore this question here: www.cell.com/trends/micro...
@cp-trendsmicrobiol.bsky.social
For download: www.sciencedirect.com/science/arti...
With @billerbecks.bsky.social we explore this question here: www.cell.com/trends/micro...
@cp-trendsmicrobiol.bsky.social
For download: www.sciencedirect.com/science/arti...
Small proteins and peptides conferring protection against antimicrobial compounds
The secretion of antimicrobials is widespread among microorganisms, many of which
have developed protection mechanisms. While well-characterized protection mechanisms
involve relatively large proteins...
www.cell.com
March 11, 2025 at 11:08 AM
Now online: can small proteins and peptides play a role in antimicrobial resistance?
With @billerbecks.bsky.social we explore this question here: www.cell.com/trends/micro...
@cp-trendsmicrobiol.bsky.social
For download: www.sciencedirect.com/science/arti...
With @billerbecks.bsky.social we explore this question here: www.cell.com/trends/micro...
@cp-trendsmicrobiol.bsky.social
For download: www.sciencedirect.com/science/arti...
Reposted by Rianne Prins
For yeast and fungi fans: I’ll be speaking about our work on the yeast toxicome on March 13th. Hybrid attendance possible.
www.imperial.ac.uk/events/18820...
www.imperial.ac.uk/events/18820...
Imperial Fungal Science Network | Seminar Series 2025 | Seminar
A hybrid seminar program focussing on our key research themes: Biotechnology and Engineering; Ecology, Evolution and the Environment.
www.imperial.ac.uk
February 26, 2025 at 7:56 AM
For yeast and fungi fans: I’ll be speaking about our work on the yeast toxicome on March 13th. Hybrid attendance possible.
www.imperial.ac.uk/events/18820...
www.imperial.ac.uk/events/18820...
Reposted by Rianne Prins
The human genome encodes potentially thousands of tiny proteins that were previously overlooked.
The search is on to find out what they do
https://go.nature.com/41amXq2
The search is on to find out what they do
https://go.nature.com/41amXq2
‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.
go.nature.com
February 11, 2025 at 11:18 AM
The human genome encodes potentially thousands of tiny proteins that were previously overlooked.
The search is on to find out what they do
https://go.nature.com/41amXq2
The search is on to find out what they do
https://go.nature.com/41amXq2
Reposted by Rianne Prins
Out now! We consolidated >600 Dutch yeast and characterised their activity against spoilage yeasts and relevant human and plant pathogens, focusing on yeasts that secrete antifungal proteins. Great resource for biocontrol and beyond.
pubmed.ncbi.nlm.nih.gov/39875071/
pubmed.ncbi.nlm.nih.gov/39875071/
February 3, 2025 at 5:05 PM
Out now! We consolidated >600 Dutch yeast and characterised their activity against spoilage yeasts and relevant human and plant pathogens, focusing on yeasts that secrete antifungal proteins. Great resource for biocontrol and beyond.
pubmed.ncbi.nlm.nih.gov/39875071/
pubmed.ncbi.nlm.nih.gov/39875071/
Reposted by Rianne Prins
Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity
Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors
A 🧵 1/10
www.cell.com/cell/abstrac...
Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors
A 🧵 1/10
www.cell.com/cell/abstrac...
Structure-guided discovery of viral proteins that inhibit host immunity
Large-scale, structure-guided computational pipeline sifts through millions of phage
proteins to identify those that bind and antagonize host immune proteins. Detected
proteins are shown to inhibit no...
www.cell.com
January 23, 2025 at 4:12 PM
Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity
Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors
A 🧵 1/10
www.cell.com/cell/abstrac...
Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors
A 🧵 1/10
www.cell.com/cell/abstrac...
Reposted by Rianne Prins
New preprint from the group of @billerbecks.bsky.social!
Alanine-scanning of the yeast killer toxin K2 reveals key residues for activity, gain-of-function variants, and supports prediction of precursor processing and 3D structure. https://www.biorxiv.org/content/10.1101/2024.11.22.624868v1
Alanine-scanning of the yeast killer toxin K2 reveals key residues for activity, gain-of-function variants, and supports prediction of precursor processing and 3D structure. https://www.biorxiv.org/content/10.1101/2024.11.22.624868v1
Yeast killer toxins (YKTs) are antimicrobial proteins secreted by yeast with potential applications
www.biorxiv.org
November 23, 2024 at 7:13 AM
New preprint from the group of @billerbecks.bsky.social!