Still no change in recommendation to not use primaquine in lactating women, despite study in Thailand showing minimal exposure to infant after 28 days. This effectively excludes a high proportion of females of child bearing age from radical cure

Tafenoquine now recommened in patients >2yrs of age with >70% G6PD activity. Restricted to coadmin with Chloroquine cos of concerns of DDI with ACT. Recommendations focused on South America, but data from Africa and Asia-Pacific is accuring

High dose primaquine (7mg/kg) recommended over 3.5mg/kg. Administered over 14 days (0.5mg/kg/day) or 7 days (1mg/kg/day). PQ7 potentially better compliance but more GI adverse events, and only recommended in patients with >70% G6PD activity (ie needs semiquant G6PD testing)

Adults usually get same dose of antimalarials irrespective of their weight. In this study dose was adjusted for weight and still suboptimal