Robert Lufkin MD
@robertlufkinmd.bsky.social
Medical school professor (UCLA & USC) and New York Times bestselling author empowering people to take back their health and live life to the fullest.
https://www.robertlufkinmd.com/
https://www.robertlufkinmd.com/
'Omics' are increasingly important in understanding our health and longevity.
I would also add could epigenomics, immunomics, microbiomics, glycomics, exposomics, etc.
What else would you include?
https://www.cell.com/neuron/fulltext/S0896-6273(25)00472-6
I would also add could epigenomics, immunomics, microbiomics, glycomics, exposomics, etc.
What else would you include?
https://www.cell.com/neuron/fulltext/S0896-6273(25)00472-6
January 5, 2026 at 7:49 PM
'Omics' are increasingly important in understanding our health and longevity.
I would also add could epigenomics, immunomics, microbiomics, glycomics, exposomics, etc.
What else would you include?
https://www.cell.com/neuron/fulltext/S0896-6273(25)00472-6
I would also add could epigenomics, immunomics, microbiomics, glycomics, exposomics, etc.
What else would you include?
https://www.cell.com/neuron/fulltext/S0896-6273(25)00472-6
This 20 year old went on to sell 164 million records and win 20 Grammys.
Who is he?
Who is he?
January 5, 2026 at 7:00 PM
This 20 year old went on to sell 164 million records and win 20 Grammys.
Who is he?
Who is he?
Under a landmark agreement reached at the Minamata Convention on Mercury in Geneva, more than 150 countries have committed to a full global phase-out of dental amalgam by 2034, marking one of the final steps in eliminating a major source of mercury pollution.
The obvious question ... @Rainmaker1973
The obvious question ... @Rainmaker1973
January 5, 2026 at 7:00 PM
Under a landmark agreement reached at the Minamata Convention on Mercury in Geneva, more than 150 countries have committed to a full global phase-out of dental amalgam by 2034, marking one of the final steps in eliminating a major source of mercury pollution.
The obvious question ... @Rainmaker1973
The obvious question ... @Rainmaker1973
It's letters like this that make it all worthwhile.
Lies I Taught in Medical School
Download sample chapter here:
https://www.robertlufkinmd.com/lies/
Lies I Taught in Medical School
Download sample chapter here:
https://www.robertlufkinmd.com/lies/
January 5, 2026 at 2:43 PM
It's letters like this that make it all worthwhile.
Lies I Taught in Medical School
Download sample chapter here:
https://www.robertlufkinmd.com/lies/
Lies I Taught in Medical School
Download sample chapter here:
https://www.robertlufkinmd.com/lies/
I walk for at least an hour every morning outside as the sun comes up.
(no matter what the weather)
~10,000 steps, morning sunlight, and mental clarity to start the day.
What are your fitness secrets?
(no matter what the weather)
~10,000 steps, morning sunlight, and mental clarity to start the day.
What are your fitness secrets?
January 4, 2026 at 2:26 PM
I walk for at least an hour every morning outside as the sun comes up.
(no matter what the weather)
~10,000 steps, morning sunlight, and mental clarity to start the day.
What are your fitness secrets?
(no matter what the weather)
~10,000 steps, morning sunlight, and mental clarity to start the day.
What are your fitness secrets?
One is unhealthy junk food.
Which one do you choose?
Which one do you choose?
January 4, 2026 at 1:57 AM
One is unhealthy junk food.
Which one do you choose?
Which one do you choose?
Tesla FSD (Full Self Driving) finally works and it turns out that it's a much better driver than I am.
The equivalent of a personal driver that frees me up for other mental activities while traveling for ~$4/day.
Is anybody else trying it?
The equivalent of a personal driver that frees me up for other mental activities while traveling for ~$4/day.
Is anybody else trying it?
January 2, 2026 at 11:54 PM
Tesla FSD (Full Self Driving) finally works and it turns out that it's a much better driver than I am.
The equivalent of a personal driver that frees me up for other mental activities while traveling for ~$4/day.
Is anybody else trying it?
The equivalent of a personal driver that frees me up for other mental activities while traveling for ~$4/day.
Is anybody else trying it?
Before we leave 2025 for good...
Here are some things I am grateful for:
2025 had the lowest rate of:
- inflation since 2020
- mass shootings since 2006
- homicides since 1950s
- teenage pregnancy ever recorded
- alcohol consumption ever recorded
- road fatalities since 2019
- drug overdose de...?
Here are some things I am grateful for:
2025 had the lowest rate of:
- inflation since 2020
- mass shootings since 2006
- homicides since 1950s
- teenage pregnancy ever recorded
- alcohol consumption ever recorded
- road fatalities since 2019
- drug overdose de...?
January 1, 2026 at 9:56 PM
Before we leave 2025 for good...
Here are some things I am grateful for:
2025 had the lowest rate of:
- inflation since 2020
- mass shootings since 2006
- homicides since 1950s
- teenage pregnancy ever recorded
- alcohol consumption ever recorded
- road fatalities since 2019
- drug overdose de...?
Here are some things I am grateful for:
2025 had the lowest rate of:
- inflation since 2020
- mass shootings since 2006
- homicides since 1950s
- teenage pregnancy ever recorded
- alcohol consumption ever recorded
- road fatalities since 2019
- drug overdose de...?
Congrats to @regan_prost on losing 110 lbs!
The smile says it all.
It's great to be healthy again!
The smile says it all.
It's great to be healthy again!
January 1, 2026 at 7:00 PM
Congrats to @regan_prost on losing 110 lbs!
The smile says it all.
It's great to be healthy again!
The smile says it all.
It's great to be healthy again!
My 2025 daily average steps: 13,548.
No wonder I feel so great!
I am on upping the number in 2026.
How are your steps going?
No wonder I feel so great!
I am on upping the number in 2026.
How are your steps going?
January 1, 2026 at 6:53 PM
My 2025 daily average steps: 13,548.
No wonder I feel so great!
I am on upping the number in 2026.
How are your steps going?
No wonder I feel so great!
I am on upping the number in 2026.
How are your steps going?
From Lab Bench To Daily Brain Care: Polysaccharides, Immunity, And Alzheimer's Breakthroughs.
https://robertlufkinmd.substack.com/
https://robertlufkinmd.substack.com/
December 30, 2025 at 5:04 PM
From Lab Bench To Daily Brain Care: Polysaccharides, Immunity, And Alzheimer's Breakthroughs.
https://robertlufkinmd.substack.com/
https://robertlufkinmd.substack.com/
For maximum longevity:
1. Never stop exercising
2. Stop drinking alcohol as early as possible
https://link.springer.com/article/10.1007/s40279-025-02360-w
h/t @GregoireMillet1
1. Never stop exercising
2. Stop drinking alcohol as early as possible
https://link.springer.com/article/10.1007/s40279-025-02360-w
h/t @GregoireMillet1
December 30, 2025 at 7:14 AM
For maximum longevity:
1. Never stop exercising
2. Stop drinking alcohol as early as possible
https://link.springer.com/article/10.1007/s40279-025-02360-w
h/t @GregoireMillet1
1. Never stop exercising
2. Stop drinking alcohol as early as possible
https://link.springer.com/article/10.1007/s40279-025-02360-w
h/t @GregoireMillet1
Magazine predictions from 1996.
How did they do?
How did they do?
December 29, 2025 at 7:00 PM
Magazine predictions from 1996.
How did they do?
How did they do?
Mitochondria: The Surprising Drivers of Chronic Disease and Longevity.
https://robertlufkinmd.substack.com/p/mitochondria-the-surprising-drivers
On our new weekly Health Longevity Secrets Substack.
Please support us by subscribing (free).
https://robertlufkinmd.substack.com/p/mitochondria-the-surprising-drivers
On our new weekly Health Longevity Secrets Substack.
Please support us by subscribing (free).
December 29, 2025 at 8:26 AM
Mitochondria: The Surprising Drivers of Chronic Disease and Longevity.
https://robertlufkinmd.substack.com/p/mitochondria-the-surprising-drivers
On our new weekly Health Longevity Secrets Substack.
Please support us by subscribing (free).
https://robertlufkinmd.substack.com/p/mitochondria-the-surprising-drivers
On our new weekly Health Longevity Secrets Substack.
Please support us by subscribing (free).
Both versions are unhealthy junk food.
But we managed to make it even worse in the US version.
Why?
But we managed to make it even worse in the US version.
Why?
December 27, 2025 at 7:17 PM
Both versions are unhealthy junk food.
But we managed to make it even worse in the US version.
Why?
But we managed to make it even worse in the US version.
Why?
I now take creatine on a regular basis for my health and longevity.
Everyday.
Even on days I am not lifting weights.
What about you?
Everyday.
Even on days I am not lifting weights.
What about you?
December 26, 2025 at 11:17 PM
I now take creatine on a regular basis for my health and longevity.
Everyday.
Even on days I am not lifting weights.
What about you?
Everyday.
Even on days I am not lifting weights.
What about you?
It's better to be the oldest at the gym,
than the youngest at the nursing home.
than the youngest at the nursing home.
December 26, 2025 at 7:00 PM
It's better to be the oldest at the gym,
than the youngest at the nursing home.
than the youngest at the nursing home.
Even as a doctor, I've come to understand something important:
Doctors don't make us healthy.
They help us manage illness.
True health?
That's something we create ourselves—through the daily lifestyle choices we make in how we live, eat, move, and rest.
Agree?
Doctors don't make us healthy.
They help us manage illness.
True health?
That's something we create ourselves—through the daily lifestyle choices we make in how we live, eat, move, and rest.
Agree?
December 25, 2025 at 11:52 PM
Even as a doctor, I've come to understand something important:
Doctors don't make us healthy.
They help us manage illness.
True health?
That's something we create ourselves—through the daily lifestyle choices we make in how we live, eat, move, and rest.
Agree?
Doctors don't make us healthy.
They help us manage illness.
True health?
That's something we create ourselves—through the daily lifestyle choices we make in how we live, eat, move, and rest.
Agree?
New study: 1 in 5 elite rowers develops atrial fibrillation later in life.
Extreme endurance training may remodel the heart—but not always in a good way.
Optimized Performance ≠ Optimized Longevity
https://t.co/7jDMvhrSRL
h/t @outbreakupdates
Extreme endurance training may remodel the heart—but not always in a good way.
Optimized Performance ≠ Optimized Longevity
https://t.co/7jDMvhrSRL
h/t @outbreakupdates
December 21, 2025 at 4:00 PM
New study: 1 in 5 elite rowers develops atrial fibrillation later in life.
Extreme endurance training may remodel the heart—but not always in a good way.
Optimized Performance ≠ Optimized Longevity
https://t.co/7jDMvhrSRL
h/t @outbreakupdates
Extreme endurance training may remodel the heart—but not always in a good way.
Optimized Performance ≠ Optimized Longevity
https://t.co/7jDMvhrSRL
h/t @outbreakupdates
It doesn't have to be this way.
ht/t @AlpacaAurelius
ht/t @AlpacaAurelius
December 20, 2025 at 6:00 PM
It doesn't have to be this way.
ht/t @AlpacaAurelius
ht/t @AlpacaAurelius
If you need a chemistry degree to decipher the ingredient list on your food,
it's probably not food.
h/t @JosephRudys
it's probably not food.
h/t @JosephRudys
December 20, 2025 at 4:14 PM
If you need a chemistry degree to decipher the ingredient list on your food,
it's probably not food.
h/t @JosephRudys
it's probably not food.
h/t @JosephRudys
I just arrived from sea level to 8,000 feet, and the first night my O₂ sat fell to 93%.
Once my erythropoietin ramped up and pumped out more red blood cells, I was back to 97% the next night.
What an incredible homeostatic machine the human body is.
Once my erythropoietin ramped up and pumped out more red blood cells, I was back to 97% the next night.
What an incredible homeostatic machine the human body is.
December 20, 2025 at 1:33 AM
I just arrived from sea level to 8,000 feet, and the first night my O₂ sat fell to 93%.
Once my erythropoietin ramped up and pumped out more red blood cells, I was back to 97% the next night.
What an incredible homeostatic machine the human body is.
Once my erythropoietin ramped up and pumped out more red blood cells, I was back to 97% the next night.
What an incredible homeostatic machine the human body is.
Why mitochondria are more like the motherboard than the powerhouse of the cell.
https://www.scientificamerican.com/article/why-mitochondria-are-more-like-a-motherboard-than-the-powerhouse-of-the-cell/
https://www.scientificamerican.com/article/why-mitochondria-are-more-like-a-motherboard-than-the-powerhouse-of-the-cell/
December 19, 2025 at 7:57 PM
Why mitochondria are more like the motherboard than the powerhouse of the cell.
https://www.scientificamerican.com/article/why-mitochondria-are-more-like-a-motherboard-than-the-powerhouse-of-the-cell/
https://www.scientificamerican.com/article/why-mitochondria-are-more-like-a-motherboard-than-the-powerhouse-of-the-cell/
Please join me in London or via zoom for this important conference in 2026.
[Use code LUFKIN10 for 10% off tickets.]
[Use code LUFKIN10 for 10% off tickets.]
December 19, 2025 at 5:39 PM
Please join me in London or via zoom for this important conference in 2026.
[Use code LUFKIN10 for 10% off tickets.]
[Use code LUFKIN10 for 10% off tickets.]