Alport syndrome in middle aged man with hx of hearing impair. Presents with proteinuria, RBC 3-5, UPCR 4, SCr 2.5. Characteristic interstitial foam cells noted. #renalpath #pathsky #nephrology

Persona Analysis: The Clinical Philosopher with 92% authenticity!

blueskyroast.com/roast/roboon...

How can we tell that the ones with hollow core are not immunotactoid GN?

That's correct. Lipofuscin is golden brown pigment associated with senescent cells. It is composed of degraded protein & lipid from cell membrane breakdown, probably due to decreased lysosome function
journals.lww.com/kidney360/fu...

What are the pigments in tubular cells? The bx is from 85 yo female with nephrotic syndrome and AKI. #renalpathology #pathsky

30 yo F 6 days PO with delayed graft function. Bx shows acute tubular injury with extensive calcium oxalate crystal deposits. Graft function improves after supportive treatment. Unclear cause. #renalpath #pathsky #nephrology

Is AIN also a finding in contrast nephropathy?