RootPath
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rootpath.com
RootPath
@rootpath.com
RootPath is a pioneer in NextGen gene synthesis and SynBio solutions. With large libraries of clonal, kb-long, individually delivered genes averaging as low as $0.03/bp, as well as many other gene library products, we enable biology at scale.
A huge thank you to all participants and reviewers @proftomellis.bsky.social, @atinygreencell.bsky.social, Tim Lu and @lecong.bsky.social. You really showed us how creativity and scientific rigor can make SynBio a special tool to make the world a better place. A lot more to come!
September 23, 2025 at 3:03 PM
Learn more about the #MegabaseSpark initiative: bit.ly/450ip7Z
August 4, 2025 at 3:23 PM
"By engineering precise, tuneable expression systems with optimized protocols, this project will pioneer reliable microbiome-based diagnostics and therapeutics, transforming chronic colon disease management."
August 4, 2025 at 3:22 PM
Learn more about the #MegabaseSpark initiative: Learn more at bit.ly/450ip7Z
RootPath
Enabling Biology at Scale
bit.ly
July 17, 2025 at 5:39 PM
"Synthetic refactoring and optimization of a biosynthetic gene cluster encoding a potent anti-breast cancer natural product, to improve potency and production in a breast microbiome-resident bacterium."
July 17, 2025 at 5:38 PM
"Optimization of a cutting-edge system to screen vast numbers of compounds within bacterial factories as a novel type of drugs to tackle a wide array of diseases."
July 16, 2025 at 1:16 PM
"This research uses synthetic biology to determine if all 20 canonical amino acids are essential for life. By designing and testing proteins with fewer amino acids in bacteria, we aim to uncover fundamental life principles and advance protein design and synthetic biology."
June 6, 2025 at 8:16 PM
"As with software, open DNA & strains promotes innovation around the world. I wish to extend Open Yeast & Yeast Protein Expression Toolkits, now in 50 countries, to permit engineering of Yarrowia lipolytica & creating truly open chassis to support boots on the ground innovators."
May 12, 2025 at 2:38 PM
"We’re building a synthetic library of RNA sequence variants to map how mutations reshape RNA folding and function. By encoding thousands of designed variants in synthetic DNA, we aim to uncover design rules for RNA-based therapeutics and nanostructures."
May 7, 2025 at 11:40 PM
Thank you Tech Watch for the shoutout! We heard Belgium is famous for chocolate, waffles, fries and creativity of VIB researchers 😜
May 7, 2025 at 2:28 PM
Thank you Sebastian for the shoutout! And thank you for offering your time to be a reviewer!
May 6, 2025 at 4:31 PM
Thank you Dr. Ellis for the shoutout!
May 6, 2025 at 3:42 PM