A. Roshealy Brau-Rodríguez
@roshealybrau.bsky.social
Reposted by A. Roshealy Brau-Rodríguez
Excited to share our latest work led by our talented PhD student @ejsm9.bsky.social We show that Myosins X/VIIb localize F-actin to the spindle&MTOCs in oocytes. With photoswitchable Optojasp, we reveal that spindle/MTOC-localized F-actin drives spindle pole focusing &accurate chromosome segregation
Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation - Nature Communications
Errors in oocyte division can cause infertility and birth defects. Here, authors combine a genetic strategy with a novel optochemical tool to show that spindle pole-localized F-actin is essential for ...
www.nature.com
September 19, 2025 at 2:08 PM
Excited to share our latest work led by our talented PhD student @ejsm9.bsky.social We show that Myosins X/VIIb localize F-actin to the spindle&MTOCs in oocytes. With photoswitchable Optojasp, we reveal that spindle/MTOC-localized F-actin drives spindle pole focusing &accurate chromosome segregation