Ruoyan Li
@ruoyanli89.bsky.social
61 followers 89 following 1 posts
Assistant Professor at MD Anderson Cancer Center | Cancer genomics, single-cell genomics, and somatic evolution https://www.mdanderson.org/research/departments-labs-institutes/labs/ruoyan-li-laboratory.html
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Reposted by Ruoyan Li
Reposted by Ruoyan Li
imartincorena.bsky.social
Resharing here a recent X post. In this preprint, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/ www.medrxiv.org/content/10.1...
Somatic mutation and selection at epidemiological scale
As we age, many tissues become colonised by microscopic clones carrying somatic driver mutations ([1][1]–[10][2]. Some of these clones represent a first step towards cancer whereas others may contribu...
www.medrxiv.org