Excited to share new work from Sarvesh Surve examining the gut microbiota of adults with CF using colonoscopy samples and a culturomics approach. We note continued depletion of Bacteroidota (which we noted in kids) & enrichment of aerobes in the mucosa of pwCF.
pubmed.ncbi.nlm.nih.gov/41256617/

New in JB: Bedree, He & colleagues identify essential genes in the CPR basibiont Schaalia odontolytica using a TnSeq-based approach.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

The Regional Landscape of the Human Colon Culturome in Health and Cystic Fibrosis https://www.biorxiv.org/content/10.1101/2025.09.29.679198v1

I'm very excited to report that Leslie Day, a post doc in the lab, was awarded a Damon Runyon Cancer Research Fund post-doctoral fellowship to support her work over the next 4 years! Congrats to Leslie!
tinyurl.com/3p26njb6

We had the O'Toole Lab Reunion on Sat here at Dartmouth, celebrating 26 amazing years - science is all about the people, and I have been fortunate to have a great bunch of folks in the lab over the years! And THANKS to all the lab members who did all the organizing!

We gathered to say farewell to Kaitlyn Barrack as she heads off to the next step in her career! We wish her all the best - she's been an amazing PhD student.

Our newest manuscript on the gut-lung axis in CF, lead by Rebecca Valls, explores sex and intestinal regional differences in response to Bacteroides. Check it out!
www.biorxiv.org/content/10.1...

Last night at Microbial Diversity, we all went out for a MD tradition- the Volta experiment! A dirty but happy crew!
@mblscience.bsky.social

Day 2 of the retreat also means a lobster dinner, a view of the light house and some blueberry pie!

Day 2 of the retreat! Surface sensing (Shawna and Robert) and Bacteroides in the CF gut (Sarvesh) were the topics of the day - we had some great discussions.