Science in Boston
@scienceinboston.com
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Your complete source for life science news and events in the Greater Boston Area. Brought to you by the Science in the City program at @stemcell.com.
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A new paper by @ragoninstitute.bsky.social biostatisticians in the Ghebremichael Lab introduces and tests a flexible way to grade medical tests like blood-based #biomarkers so scientists can more confidently tell which ones truly separate “sick” from “healthy.”

Learn more: https://bit.ly/4pTUDT7
Reposted by Science in Boston
scientifyresearch.org
The #scientifyRESEARCH #SciComm Award returns, this year highlighting rare disease research! Researchers: Translate your peer-reviewed work for the public. Sign up for updates: www.scientifyresearch.org/rare-disease...
Partner or sponsor? Contact us: [email protected]
#RareDisease
scientifyRESEARCH Rare disease advances science communication award inspiring hope through science storytelling
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Dr. Ryan Logan at @umasschan.bsky.social is a principal investigator on three NIH grants, totaling nearly $10 million in research support for his work investigating the underlying biology of #OpioidUseDisorder.

Congratulations! https://bit.ly/438Sl8T
Reposted by Science in Boston
harvardcatalyst.bsky.social
Free consulting service. NIH K grant applicants: Apply to receive tailored feedback on your draft Specific Aims page & attend a career development consult with a Harvard-affiliated distinguished mentor. Free for @harvard.edu affiliates. Apply: hvrdct.me/947b9d
Free consultation service for Harvard-affiliated researchers. K Grant Specific Aims & Career Development.
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Drs. Volker Hovestadt and Gabriel Griffin at @danafarber.bsky.social have developed a groundbreaking diagnostic tool, called MARLIN, that could transform the way acute #leukemia is identified and treated.

⚙️ Press release: https://bit.ly/4pUDBEt
🧪 Abstract: https://go.nature.com/48ea16t
scienceinboston.com
🩸 The @wyssinstitute.bsky.social has received Wellcome Leap funding to develop the first-ever human Organ Chip model for heavy menstrual bleeding. This work led by Dr. Don Ingber could transform our understanding of #ReproductiveHealth and lead to better treatments.

See more: https://bit.ly/3KBzcGe
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Mucus contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection.

In a new study, @mit.edu researchers have identified mucins that defend against #Salmonella and other bacteria that cause diarrhea 💩: https://bit.ly/4o30C6z
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A new @cp-cellreports.bsky.social study from Drs. Andrea Papadopoulos & Zaza Ndhlovu at the @ragoninstitute.bsky.social explains how HIV survives in lymph nodes during treatment. They showed that the virus weakens nearby “killer” CD8 T cells from inside B cell follicles.

🕵️ https://bit.ly/48HI6vV
scienceinboston.com
Researchers at @mit.edu have now found a way to dramatically lower the error rate of prime editing.

This advance could make it easier to develop gene therapy treatments, according to Dr. Phillip Sharp, senior author of the study.

🧬 https://go.nature.com/4pvgksB
📰 https://bit.ly/4nEeIuI
scienceinboston.com
👏 PhD candidate Jessica Peura from @umasschan.bsky.social earned a Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship from the National Cancer Institute!

Peura's research analyzes how cancer spreads: https://bit.ly/429HoDJ
scienceinboston.com
🥽 New research from the Maus and Manguso labs at @harvardmed.bsky.social has identified genetic modifications that may increase the effectiveness of immunotherapy for #MultipleMyeloma, a difficult-to-treat blood cancer.

Press release: https://bit.ly/3W6V3b0
Abstract: https://go.nature.com/3W6V2Uu
scienceinboston.com
🍎 Two @harvardmcb.bsky.social educators have been recognized with the Anya Bernstein Bassett Award for Excellence in Teaching. This award celebrates outstanding non-ladder faculty who are primarily focused on teaching.

Congratulations to Drs. Sien Verschave and Alain Viel! https://bit.ly/42HwfKn
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Check out this article to see the highlighted work from Dr. George Church at @harvardmed.bsky.social and previous Boston researchers Drs. Timothy Lu and Jay Shendure!
natureportfolio.nature.com
A technology feature in Nature describes how scientists are outfitting cells with the molecular equivalent of flight records, which allows them to log, in real time, the signals that cells receive, the paths they travel and the decisions they make. 🧬 🧪
Real-time molecular recorders expose the inner lives of cells
Gene-editing tools transform cells into record-keepers, capturing hidden timelines of health and disease.
go.nature.com
scienceinboston.com
📢 @umasschan.bsky.social has licensed worldwide rights to a long-lasting human monoclonal antibody that prevents #LymeDisease to Tonix Pharmaceuticals.

🔗 Learn more: https://bit.ly/42aiML8
scienceinboston.com
A new study led by Dr. Upasana Das Adhikari, Dr. Douglas Kwon's lab, and collaborators shows how energy use by gut immune cells can weaken the intestinal lining in people living with #HIV, even when the virus is controlled by treatment.

https://bit.ly/3Kh01zp
scienceinboston.com
Drs. Vikash Chauhan, Phillip Sharp, and Robert Langer from @mit.edu have dramatically lowered the error rate of prime editing, a technique that holds potential for treating many #GeneticDisorders.

🥼 Abstract: https://go.nature.com/4pvgksB
🗞️ Press release: https://bit.ly/4nEeIuI
scienceinboston.com
🧪 Cache DNA, a biotech out of @mit.edu, has developed technologies that preserve #biomolecules at room temperature. This will make storing and transporting samples less expensive and more reliable.

Learn more from CEO Dr. James Banal: https://bit.ly/46b21BT
Reposted by Science in Boston
wyssinstitute.bsky.social
"We're thinking about any way we can get this to patients. That's the whole point of what we're trying to do," explains Paul Stankey, a researcher in Core Faculty member Jennifer Lewis' lab. Learn what it will take to scale up their work and bring their technologies to patients.
Boston’s Additive Edge: Inside Harvard’s Lewis Lab and the Road to Patients, Part II - 3DPrint.com | Additive Manufacturing Business
When I visited Jennifer Lewis’s lab earlier this summer, doctoral researcher Paul Stankey showed me how the team is laying the groundwork for bioprinting, from stem cells to vascular networks...
3dprint.com
scienceinboston.com
The @sitcancer.bsky.social Fellowship program helps cultivate the next generation of cancer immunotherapy experts.

🎉 Congratulations to the 2025 Fellows: Drs. Mohamad Ali Najia from @bostonchildrens.bsky.social and Ivan Pires from Brigham and Women's Hospital! https://bit.ly/46a0dcr
scienceinboston.com
An adeno-associated virus (#AAV) produced by Dr. Guangping Gao's team at @umasschan.bsky.social was used to deliver an #HIV broadly neutralizing antibody that protected preclinical animal models from HIV.

Abstract in @nature.com: https://go.nature.com/4lwHts2
Press release: https://bit.ly/41V2kOC
Reposted by Science in Boston
whiteheadinstitute.bsky.social
"What strikes me is how much excitement has grown and community has been rallied around this idea of integrating biology with cutting-edge AI," Valhalla Fellow Allison Hamilos says.

Whitehead Innovation Initiative gains momentum after a year of successes: wi.mit.edu/news/whitehe...
scienceinboston.com
In a new study appearing in Cell Genomics, a team from @mit.edu has reported that a cell’s memory is set not by on/off switching but through a more graded, dimmer-like dial of #GeneExpression.

💭 Learn more: https://bit.ly/3IpU2Yq