Charlotte
@scienceshrike.bsky.social
A 6th year Cellular & Molecular Biology graduate student working with the model Xenopus laevis at UW-Madison. (She/Her) 🐸
Reposted by Charlotte
Congratulations to Judge Susan Crawford on her victory, and to the people of Wisconsin for electing a judge who believes in the rule of law and protecting our freedoms.
April 2, 2025 at 2:45 AM
Congratulations to Judge Susan Crawford on her victory, and to the people of Wisconsin for electing a judge who believes in the rule of law and protecting our freedoms.
Reposted by Charlotte
New online! Cytoplasmic mRNA decay and quality control machineries in eukaryotes
Cytoplasmic mRNA decay and quality control machineries in eukaryotes
Nature Reviews Genetics, Published online: 27 January 2025; doi:10.1038/s41576-024-00810-1In this Review, Dowdle and Lykke-Andersen discuss advances in our understanding of the machinery and mechanisms involved in the control of cytoplasmic mRNA decay and…
go.nature.com
January 27, 2025 at 2:24 PM
New online! Cytoplasmic mRNA decay and quality control machineries in eukaryotes
Reposted by Charlotte
Read my review!
New online! Cytoplasmic mRNA decay and quality control machineries in eukaryotes
Cytoplasmic mRNA decay and quality control machineries in eukaryotes
Nature Reviews Genetics, Published online: 27 January 2025; doi:10.1038/s41576-024-00810-1In this Review, Dowdle and Lykke-Andersen discuss advances in our understanding of the machinery and mechanisms involved in the control of cytoplasmic mRNA decay and…
go.nature.com
January 28, 2025 at 6:14 PM
Read my review!
Reposted by Charlotte
I’m excited to share this story. We found that mutating an RNA binding protein’s ability to bind RNA did not remove all biological function, but when combined with a mutation that affects protein interactions, the RBP no longer functioned.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA
Like all canonical PUF proteins, C. elegans FBF-2 binds to specific RNAs via tripartite recognition motifs (TRMs). Here we report that an FBF-2 mutant protein that cannot bind to RNA, is nonetheless b...
www.biorxiv.org
October 26, 2024 at 11:42 AM
I’m excited to share this story. We found that mutating an RNA binding protein’s ability to bind RNA did not remove all biological function, but when combined with a mutation that affects protein interactions, the RBP no longer functioned.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...