Lu Yang
banner
scientafic.com
Lu Yang
@scientafic.com
Please check out my work, now published in JBC. I show that metaphase spread separates chromosomes by decondensing chromatin, as chromatin condensation forces "stick" chromosomes and extrachromosomal DNA to each other. The forces can be overcome with HDACi and Ki67.
www.jbc.org/article/S002...
Redirecting
doi.org
January 22, 2026 at 9:32 PM
I wrote a post about my research on the mitotic inheritance of extrachromosomal DNA:
scientafic.com/2025/08/30/e...

the preprint can be found on biorxiv:
www.biorxiv.org/content/10.1...

#science #biology #cancerresearch
“Water and soap” wash oncogene-containing extra-chromosomal DNA out of cancer cell nuclei
My work on the mitotic inheritance of extrachromosomal DNA (ecDNA) in cancer is now available as a preprint on bioRxiv1. In this post, I try to summarize the scientific process and a few of the mai…
scientafic.com
August 31, 2025 at 5:36 AM
Reposted by Lu Yang
Do you get SPAM conference invitation emails? Well, we replied to one and ended up going on quite an adventure. Listen to the story on the latest episode of #recscipod

open.spotify.com/episode/0YMR...

#spam #science #recreationalscience
Replying to SPAM scientific conference invitation emails (special episode)
Recreational Science · Episode
open.spotify.com
August 5, 2025 at 8:13 PM
Reposted by Lu Yang
I am a professor at Columbia University. All of the student NIH training grants have been canceled and now there are reports that ALL funding will be frozen. Why are Universities not banding together and speaking out publicly and forcibly about governmental attacks on biomedical research?
April 11, 2025 at 4:53 PM
Reposted by Lu Yang
A reminder that if the government can send migrants to a prison camp without any due process, it can send U.S. citizens there, too. I know because this happened to me and my family in 1942.
April 7, 2025 at 8:30 PM
What is the difference between good science and great science? scientafic.com/2025/03/31/g...
Good Science vs. Great Science
Good science is rigorously following the scientific method. It is about minimizing assumptions, prejudices, and human fallacies. Good science is the unbiased collection and analysis of evidence to …
scientafic.com
March 31, 2025 at 5:10 PM
Reposted by Lu Yang
The first episode of our podcast, Recreational Science, is out now! Please check it out wherever podcasts are found! #science #comedy #podcast open.spotify.com/episode/7kiZ...
Fruit bat foreplay and electric anti-venom
Recreational Science · Episode
open.spotify.com
March 30, 2025 at 6:44 PM
How do we improve citations as a metric of a publication's impact? Here I propose something I call the Distinct Citations Index: scientafic.com/2025/03/28/t...

#science
The Distinct Citations Index
In my post “Science Has an Economics Problem,” I noted how the number of citations a published scientific article receives is not a true indicator of the study’s impact and says n…
scientafic.com
March 29, 2025 at 5:22 PM
In my upcoming series of blogs, I'll write about some of my (theoretical) indices for assessing scientific productivity. Check them out!
scientafic.com/2025/03/27/science-has-an-economics-problem/
Science has an economics problem
Before I dive into the main topic of this post, I would just like to point out that when your car has an engine issue, you go to a mechanic to get the problem expertly diagnosed and fixed. Apparent…
scientafic.com
March 28, 2025 at 6:23 AM