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scireq.bsky.social
SCIREQ an EMKA TECH Company
@scireq.bsky.social
13 followers 14 following 20 posts
emka TECHNOLOGIES and SCIREQ provide advanced research instruments and telemetry solutions for in vivo, in vitro, and ex vivo studies in physiology, pharmacology, and toxicology. Cited in over 7,500 publications, our tools ensure precise, reproducible resu
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scireq.bsky.social
A recent study by Wang et al. (2024) explores how nanodrug carriers, such as liposomes, behave under different breathing conditions. Read the full blog here: hubs.ly/Q03XQT8k0

#SCIREQ #LungonChip #nanoDrug #respiratoryResearch #inExpose
Breathing Life into Nanodrug Research: A Lung-on-Chip Revolution
Traditional aerosol exposure systems often fall short in replicating the complex dynamics of human breathing in a controlled lab setting.
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December 11, 2025 at 3:01 PM
scireq.bsky.social
As IPF develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. A recent study by Lee et al. (2024) introduces aerosolizable inhaled microgels designed to deliver pirfenidone and nintedanib directly to the lungs. hubs.ly/Q03GVzcl0
Shaping the Future of Pulmonary Fibrosis Therapy with Inhaled Microgels
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue.
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September 16, 2025 at 1:28 PM
scireq.bsky.social
This blog discusses a study by Bohorquez et al. (2024) who developed a humanized NSG-SGM3 mouse model to advance HIV/TB co-infection studies, a model that has been lacking in co-infection research. Full blog: hubs.ly/Q03tNQGM0

#flexiVent #flexiVentLungFunction #TB #Tuberculosis #HIV
Advanced Lung Function Measurement In A Novel HIV/TB Co-infection in Mouse Models
Tuberculosis and Human Immunodeficiency Virus are major global health threats. Their interaction worsens disease severity, as HIV reduces CD4+ T cells, making individuals more vulnerable to TB.
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June 26, 2025 at 1:05 PM
scireq.bsky.social
Five years since the onset of the COVID-19 pandemic, the scientific community delved deep into the mysteries of the SARS-CoV-2. This blog explains the nuances of a new conditional mouse model called Rosa26 creERT2/chACE2. Full blog here: www.scireq.com/a-new-mouse-...
A New Mouse Model for SARS-CoV-2 Studies Beyond The Respiratory System
For five years since the onset of the COVID-19 pandemic, the scientific community delved deep into the mysteries of the SARS-CoV-2 virus, to understand its impact on our health and develop antiviral t...
www.scireq.com
June 9, 2025 at 1:55 PM
scireq.bsky.social
Another year, another SCIREQ Booth at the #ATS2025 conference. Our scientific pulmonary team is excited to meet you at booth 626 ... pass by for memorable surprise !

www.scireq.com/trade-shows/...
ATS 2025
The 2025 American Thoracic Society Conference will take place in San Francisco, CA from May 18th to May 20th, 2025 at the San Francisco Moscone Center
www.scireq.com
May 13, 2025 at 12:51 PM
scireq.bsky.social
This year during the @atscommunity.bsky.social 2025 Conference, SCIREQ will be hosting an evening Scientific Session. The event will be followed by drinks and appetizers ! Register now, seats are limited: hubs.ly/Q03lNL290
ATS 2025 Exhibitor Hosted Session Registration
SCIREQ will be hosting a free in-person Infectious Diseases panel discussion on May 20th from 4-5 PM at The Howard SF
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May 13, 2025 at 12:49 PM
scireq.bsky.social
It is day 1 of the 2025 #APSSummit
Swing by booth #912 to meet our experts and discuss your latest research !

#SCIREQ #emka #PhysiologyResearch #APS2025
April 25, 2025 at 2:24 PM
scireq.bsky.social
Swing by our booth at the BIOTECH CONNECT Expo next Thursday in Montreal ! Our team is excited to meet you and explore all the new local innovation and research projects 🔬🔎

#SCIREQ #RespiratoryResearch #Montreal
April 17, 2025 at 1:01 PM
scireq.bsky.social
This blog highlights studies that utilized #vivoFlow + plethysmography to monitor respiratory metrics in preclinical RTT models. When combined with #easyTEL+ telemetry, these technologies improve the assessment of multi-system involvement in RTT pathology and treatment response:
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Advanced Respiratory And Multi-Parameter Monitoring In Preclinical Models Of Rett Syndrome
Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by mutations in the MECP2 gene, leading to various symptoms, including cognitive impairment, motor dysfunction, and significant respi...
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April 8, 2025 at 1:22 PM
scireq.bsky.social
This recent blog features a study by Beck et al (2023) which developed a first-in-class, carbohydrate-coupled inhibitor of microRNA-21 (RCS-21), that shows significant potential as a therapeutic agent: www.scireq.com/treating-acu...

#LungFunction #FlexiVent #SCIREQ
Treating Acute Inflammatory Lung Disease: The Promise of Trimannose-Coupled antimiR-21
Recent advances in the fight against severe acute inflammatory lung diseases, including COVID-19, have revealed a promising new approach to treating pulmonary hyperinflammation and long-term lung dama...
www.scireq.com
April 1, 2025 at 12:45 PM
scireq.bsky.social
As cannabis use increases, so does the availability of products marketed as safe alternatives to smoking. This blog explores a recent study by Wilson et al (2025) that examined the effects of dry herb cannabis vapor on lung epithelial cells. Read the full blog here: www.scireq.com/the-impact-o...
The Impact of Cannabis Vapor on the Lungs and What We Learn from the Right Model
As cannabis use increases, so does the availability of products marketed as safe alternatives to smoking. One of these products is the dry herb vaporizer, which heats the cannabis flower without burni...
www.scireq.com
March 25, 2025 at 1:05 PM
scireq.bsky.social
Congratulations to Kolawole Adesina on winning the #SOT2025 IRSS emka-SCIREQ Award for his Respiratory Academic Research !

#ToxExpo2025 #AcademicAwards #RespiratoryResearch #emkaSCIREQ #SCIREQ
March 19, 2025 at 6:02 PM
scireq.bsky.social
It is Day 1 of hashtag#ToxExpo2025, head over to booths 1140 & 1142 to meet our Cardio and Respiratory experts and discuss your latest studies !

#emkaTech #SCIREQ #Cardio #RespiratoryResearch #CardioPulmonary #SOT2025
March 17, 2025 at 2:34 PM
scireq.bsky.social
A new study published in Antioxidants sheds light on the role of Paraoxonase 2 (PON2) in defending airway epithelial cells against oxidant stress, offering potential insights for managing T2-low asthma—a challenging subtype with limited treatment options. www.mdpi.com/2076-3921/13... #flexiVent
Role of Paraoxonase 2 in Airway Epithelial Response to Oxidant Stress
Asthma is a widespread chronic lung disease characterized by airway inflammation and hyperresponsiveness. This airway inflammation is classified by either the presence (T2-high) or absence (T2-low) of...
www.mdpi.com
February 11, 2025 at 1:28 PM
scireq.bsky.social
New research from University College Dublin reveals that airway macrophages rely on glycolysis to maintain lung function and control responses to allergens. This finding suggests that targeting AM metabolism could be a promising strategy to manage lung diseases. Read more here: hubs.ly/Q02Zr5JQ0
Airway macrophage glycolysis controls lung homeostasis and responses to aeroallergen
The lungs represent a dynamic microenvironment where airway macrophages (AMs) are the major lung-resident macrophages. AMs dictate the balance between…
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February 4, 2025 at 1:42 PM
scireq.bsky.social
A new study published in the Journal of Pharmaceutical Analysis explores the important role of calcium channel subunit CaV1.2 in mast cell activation and allergic inflammation
Read the full study here: hubs.ly/Q02Zpfmp0

#flexiVentLungFunction #AllergyResearch #CaV1.2 #Pharmacology #DrugDevelopment
Depression of CaV1.2 activation and expression in mast cells ameliorates allergic inflammation diseases
Allergic inflammation is closely related to the activation of mast cells (MCs), which is regulated by its intracellular Ca2+ level, but the intake and…
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January 28, 2025 at 2:04 PM
scireq.bsky.social
New research in Scientific Reports from the Drs. Bill Ameredes and Ramkumar Menon labs from the University of Texas Medical Branch uncovers how fetal microchimeric cells—fetal cells present in maternal tissues—impact maternal lung health after term and preterm births. hubs.ly/Q02ZlVcG0
Fetal microchimeric cells influence maternal lung health following term and preterm births - Scientific Reports
Scientific Reports - Fetal microchimeric cells influence maternal lung health following term and preterm births
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January 21, 2025 at 2:06 PM
Reposted by SCIREQ an EMKA TECH Company
ajrcmb.bsky.social
Precision-Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research: An Official American Thoracic Society Workshop Report
@atscommunity.bsky.social #medsky

🔓 Open Access

🔗 tinyurl.com/mwxrej45
January 10, 2025 at 7:53 PM
scireq.bsky.social
A new study in the Journal of Translational Medicine highlights how ficolin-1 may revolutionize treatment for fibrotic lung diseases. Using advanced tools in the #flexiVent researchers discovered that it directly binds to TGF-β1, significantly reducing its harmful effects: hubs.ly/Q02-XcmJ0
Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1 - Journal of Translational Medicine
Background Ficolins were originally identified as proteins that bind to transforming growth factor-β1 (TGF-β1). They are capable of activating the complement system through lectin pathway for immune s...
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January 14, 2025 at 2:04 PM
scireq.bsky.social
New research published in Pediatric Research from the University of Colorado School of Medicine
highlights how the drug Nintedanib may help preserve lung growth and prevent pulmonary hypertension in cases of hyperoxia-induced lung injury—a model for Bronchopulmonary Dysplasia
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Nintedanib preserves lung growth and prevents pulmonary hypertension in a hyperoxia-induced lung injury model - Pediatric Research
Pediatric Research - Nintedanib preserves lung growth and prevents pulmonary hypertension in a hyperoxia-induced lung injury model
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January 9, 2025 at 2:15 PM
scireq.bsky.social
Recent publications by @owlstonemedical.bsky.social Medical introduce a novel method for capturing VOCs from the breath of intubated mouse models that integrates advanced sorbent tube technology with the #flexiVent system.

Read more in the full blog: hubs.ly/Q031fHCS0
New Methodology: Analyzing Volatile Organic Compounds With The flexiVent System
Volatile organic compounds (VOCs) in breath are emerging as vital biomarkers in medical research, offering a non-invasive glimpse into metabolic and physiological processes. A recent publication by Ta...
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January 7, 2025 at 2:08 PM
Reposted by SCIREQ an EMKA TECH Company
emkatech.bsky.social
Le groupe emka TECHNOLOGIES et SCIREQ Scientific Respiratory Equipment Inc.
est fier d’accueillir Mr Louis Laflamme au sein de son conseil d’administration.
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We are proud to welcome Mr Louis Laflamme to our board of directors.
www.emkatech.com/news/press-r...
December 10, 2024 at 3:10 PM