Subhajit Dutta
@sdutta.bsky.social
Exploring cell and molecular biology; cell migration & communication; telomere biology & tumour microenvironment; genomics & microscopy data analysis; he/him
Telomeric attrition potentiates p53 activation followed by the repression of PGC-1α and PGC-1β pathway of mitochondrial biogenesis. Telomeric damage orchestrate mitochondriopathy induces apoptotic pathways, proliferative checkpoints, ROS generation and it diminishes OXPHOS regulating signalling.
September 29, 2023 at 7:55 PM
Telomeric attrition potentiates p53 activation followed by the repression of PGC-1α and PGC-1β pathway of mitochondrial biogenesis. Telomeric damage orchestrate mitochondriopathy induces apoptotic pathways, proliferative checkpoints, ROS generation and it diminishes OXPHOS regulating signalling.