Sensible Medicine
@sensiblemed.skystack.xyz
Common sense and original thinking in bio-medicine
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This is an automated Substack Account of https://sensiblemed.substack.com
Discover more/Create at: @skystack.xyz
When to treat (or not treat) a high cholesterol • Drs Andrew Foy and Venk Murthy help me sort out a controversial post on X about not treating a person with a high cholesterol but very low estimated ASCVD risk on the pooled cohort equation
When to treat (or not treat) a high cholesterol
Drs Andrew Foy and Venk Murthy help me sort out a controversial post on X about not treating a person with a high cholesterol but very low estimated ASCVD risk on the pooled cohort equation
www.sensible-med.com
January 18, 2026 at 5:44 PM
When to treat (or not treat) a high cholesterol • Drs Andrew Foy and Venk Murthy help me sort out a controversial post on X about not treating a person with a high cholesterol but very low estimated ASCVD risk on the pooled cohort equation
Learning Medicine Requires Learning a New Language • Repurposed medicalese
Learning Medicine Requires Learning a New Language
Repurposed medicalese
www.sensible-med.com
January 18, 2026 at 11:42 AM
Learning Medicine Requires Learning a New Language • Repurposed medicalese
Publish Peer Reviews! • Four suggestions to improve the medical literature
Publish Peer Reviews!
Four suggestions to improve the medical literature
www.sensible-med.com
January 16, 2026 at 11:47 AM
Publish Peer Reviews! • Four suggestions to improve the medical literature
The Best Studies of 2025 for Hospital Medicine • What changed practice, what confirmed it, and what absolutely should not
The Best Studies of 2025 for Hospital Medicine
What changed practice, what confirmed it, and what absolutely should not
www.sensible-med.com
January 15, 2026 at 2:47 PM
The Best Studies of 2025 for Hospital Medicine • What changed practice, what confirmed it, and what absolutely should not
This Fortnight in Medicine XVII • Carotid revascularization, vagal nerve simulation, and some friendly disagreement.
This Fortnight in Medicine XVII
Carotid revascularization, vagal nerve simulation, and some friendly disagreement.
www.sensible-med.com
January 14, 2026 at 11:47 AM
This Fortnight in Medicine XVII • Carotid revascularization, vagal nerve simulation, and some friendly disagreement.
2024-2025 COVID-19 Vaccine Effectiveness in Pediatric Patients: A Response
2024-2025 COVID-19 Vaccine Effectiveness in Pediatric Patients: A Response
www.sensible-med.com
January 13, 2026 at 11:47 AM
2024-2025 COVID-19 Vaccine Effectiveness in Pediatric Patients: A Response
Food may be medicine but it is not an easy one to give nor is it very effective • We here at Sensible Medicine love randomized trials, but they don't always answer important questions especially when Medicine leaves its area of expertise
Food may be medicine but it is not an easy one to give nor is it very effective
We here at Sensible Medicine love randomized trials, but they don't always answer important questions especially when Medicine leaves its area of expertise
www.sensible-med.com
January 12, 2026 at 2:47 PM
Food may be medicine but it is not an easy one to give nor is it very effective • We here at Sensible Medicine love randomized trials, but they don't always answer important questions especially when Medicine leaves its area of expertise
An Important Article? • What a positive study of vagal nerve stimulation in rheumatoid arthritis might tell us about the doctor patient relationship.
An Important Article?
What a positive study of vagal nerve stimulation in rheumatoid arthritis might tell us about the doctor patient relationship.
www.sensible-med.com
January 9, 2026 at 11:47 AM
An Important Article? • What a positive study of vagal nerve stimulation in rheumatoid arthritis might tell us about the doctor patient relationship.
Why Healthcare Commentators (and Doctors) are Afraid of the Free-Market • Our view of a moral doctor is anti-free-market, and that needs to change
Why Healthcare Commentators (and Doctors) are Afraid of the Free-Market
Our view of a moral doctor is anti-free-market, and that needs to change
www.sensible-med.com
January 8, 2026 at 11:47 AM
Why Healthcare Commentators (and Doctors) are Afraid of the Free-Market • Our view of a moral doctor is anti-free-market, and that needs to change
A Trial of a Novel modRNA Flu Shot: Not So Hot • We are pleased to publish this guest critical appraisal of a recent influenza vaccine RCT--from Johns Hopkins cardiologist, Dr Joseph Marine
A Trial of a Novel modRNA Flu Shot: Not So Hot
We are pleased to publish this guest critical appraisal of a recent influenza vaccine RCT--from Johns Hopkins cardiologist, Dr Joseph Marine
www.sensible-med.com
January 7, 2026 at 11:46 AM
A Trial of a Novel modRNA Flu Shot: Not So Hot • We are pleased to publish this guest critical appraisal of a recent influenza vaccine RCT--from Johns Hopkins cardiologist, Dr Joseph Marine
Who Do You Want at a Family Picnic? • If we want nice things, like functional primary care, we need to pay for them.
Who Do You Want at a Family Picnic?
If we want nice things, like functional primary care, we need to pay for them.
www.sensible-med.com
January 6, 2026 at 11:46 AM
Who Do You Want at a Family Picnic? • If we want nice things, like functional primary care, we need to pay for them.
Prevention is a challenge in younger patients; it’s near impossible in older patients • Yet another study reveals the challenge of mechanical stroke prevention techniques, such as left atrial appendage closure, when applied to older patients
Prevention is a challenge in younger patients; it’s near impossible in older patients
Yet another study reveals the challenge of mechanical stroke prevention techniques, such as left atrial appendage closure, when applied to older patients
www.sensible-med.com
January 5, 2026 at 2:47 PM
Prevention is a challenge in younger patients; it’s near impossible in older patients • Yet another study reveals the challenge of mechanical stroke prevention techniques, such as left atrial appendage closure, when applied to older patients
The Ghost Patient Panel • Friday Reflection 23 Revisited
The Ghost Patient Panel
Friday Reflection 23 Revisited
www.sensible-med.com
January 2, 2026 at 11:48 AM
The Ghost Patient Panel • Friday Reflection 23 Revisited
This Fortnight in Medicine XVI • Finishing up our AUA questions.
This Fortnight in Medicine XVI
Finishing up our AUA questions.
www.sensible-med.com
December 31, 2025 at 11:38 AM
This Fortnight in Medicine XVI • Finishing up our AUA questions.
The COVID Vaccine in Young Children Is Not as Effective as the Headlines Would Have You Believe
The COVID Vaccine in Young Children Is Not as Effective as the Headlines Would Have You Believe
www.sensible-med.com
December 30, 2025 at 11:39 AM
The COVID Vaccine in Young Children Is Not as Effective as the Headlines Would Have You Believe
Prediction is Hard Especially About the Future • Cardiac risk scores can be useful for populations but not so much for you.
Prediction is Hard Especially About the Future
Cardiac risk scores can be useful for populations but not so much for you.
www.sensible-med.com
December 29, 2025 at 2:39 PM
Prediction is Hard Especially About the Future • Cardiac risk scores can be useful for populations but not so much for you.
For Christmas, A Gift of Laughter • ...and a writing and editing break for me
For Christmas, A Gift of Laughter
...and a writing and editing break for me
www.sensible-med.com
December 26, 2025 at 11:48 AM
For Christmas, A Gift of Laughter • ...and a writing and editing break for me
Holidays in the Hospital
Holidays in the Hospital
www.sensible-med.com
December 25, 2025 at 11:45 AM
Holidays in the Hospital
The Embarrassing but Necessary Lesson in a Drug Removal From the Market • Nearly everyone but Vinay Prasad was wrong about the Factor Xa reversal agent.
The Embarrassing but Necessary Lesson in a Drug Removal From the Market
Nearly everyone but Vinay Prasad was wrong about the Factor Xa reversal agent.
www.sensible-med.com
December 22, 2025 at 2:45 PM
The Embarrassing but Necessary Lesson in a Drug Removal From the Market • Nearly everyone but Vinay Prasad was wrong about the Factor Xa reversal agent.
The Ethics of PSA Testing and Cancer Screening
The Ethics of PSA Testing and Cancer Screening
www.sensible-med.com
December 19, 2025 at 11:42 AM
The Ethics of PSA Testing and Cancer Screening
Climbing Out of the Trenches: Rethinking Polarisation in Medicine
Climbing Out of the Trenches: Rethinking Polarisation in Medicine
www.sensible-med.com
December 18, 2025 at 11:42 AM
Climbing Out of the Trenches: Rethinking Polarisation in Medicine
This Fortnight in Medicine XI • A first foray into the "ask us anything" questions
This Fortnight in Medicine XI
A first foray into the "ask us anything" questions
www.sensible-med.com
December 17, 2025 at 11:42 AM
This Fortnight in Medicine XI • A first foray into the "ask us anything" questions
Heart Failure in Trials vs Heart Failure in the Average Hospital/Clinic • I was misunderstood on the Internet. Here is my explanation: it has to do with the (minimally disruptive) treatment of patients with heart failure
Heart Failure in Trials vs Heart Failure in the Average Hospital/Clinic
I was misunderstood on the Internet. Here is my explanation: it has to do with the (minimally disruptive) treatment of patients with heart failure
www.sensible-med.com
December 15, 2025 at 2:43 PM
Heart Failure in Trials vs Heart Failure in the Average Hospital/Clinic • I was misunderstood on the Internet. Here is my explanation: it has to do with the (minimally disruptive) treatment of patients with heart failure
Premier Card and Vitality Rewards™: Revenue Diversification Strategy
Premier Card and Vitality Rewards™: Revenue Diversification Strategy
www.sensible-med.com
December 13, 2025 at 11:48 AM
Premier Card and Vitality Rewards™: Revenue Diversification Strategy
Pickleball is a Threat to Public Health
Pickleball is a Threat to Public Health
www.sensible-med.com
December 12, 2025 at 11:45 AM
Pickleball is a Threat to Public Health