Sergio Alcon-Rodriguez
@sergioargz.bsky.social
PhD in Biomedicine & Molecular Oncology 👨🎓👨🔬 University of Oviedo/IUOPA/ISPA | Redox & glucose metabolism in therapy resistance development of prostate cancer.
Here we show that androgens suppress TXNIP, which acts as a tumor suppressor in prostate cancer by regulating the cell cycle and glucose metabolism. As a result, TXNIP loss during androgen-deprivation therapy promotes tumor resistance 💊.
rdcu.be/ePmhY
rdcu.be/ePmhY
TXNIP upregulation controls metabolism and cell cycle during androgen deprivation therapy in prostate cancer
Cell Death & Disease - TXNIP upregulation controls metabolism and cell cycle during androgen deprivation therapy in prostate cancer
rdcu.be
November 23, 2025 at 8:04 PM
Here we show that androgens suppress TXNIP, which acts as a tumor suppressor in prostate cancer by regulating the cell cycle and glucose metabolism. As a result, TXNIP loss during androgen-deprivation therapy promotes tumor resistance 💊.
rdcu.be/ePmhY
rdcu.be/ePmhY