Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...

So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience

@nhmrc.bsky.social

Amazing work by first author @shouyafeng.bsky.social with the support of @hudsonresearch.bsky.social and many others!!!

We tested this library of NLRP3 variants in response to stimulation, at low temperature (some patients with CAPS have temperature sensitive flares), and in response to a NLRP3 inhibitor, all of which yielded interesting results. If you have another idea, we are happy to share the library with you!

Data available through
infevers.umai-montpellier.fr
and
www.geniadb.net/app/gene/inf...
any variants we did not test yet please let me know!

A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis.
rdcu.be/d9iRG

My apologies, it looks like this meeting is not being broadcast. Depending on what you are interested to hear about, there could be some recordings or other resources I can point you towards.

A really important consideration in the study of #autoinflammatory and other primary immune diseases. Extremely interesting findings @bogunoviclab.bsky.social !

The 3rd Australian #autoinflammatory Disease Symposium will be combined with an Education Summit on Paediatric Rheumatology, in partnership with Zoe’s Angels:

21-22 Feb 2025 in Brisbane!

imb.uq.edu.au/event/20941/...

Here is a feed if you are interested to see things relating to Autoinflammation and Autoinflammatory Disease

bsky.app/profile/did:...

The premier international conference for #autoinflammatory disease research only happens every 2 years. Don't miss this next instalment in Paris April 8th to 10th 2025!

Abstract submissions closing soon.

issaid.org/issaid2025/

Looks like a great inflammazoom coming up Dec 16 with @inflammasomelab.bsky.social and Si Ming Man! These talks are great for everyone interested in autoinflammation.

Register here to access the live session as well as on-demand talks from past sessions: events.abcam.com/AnYVL?rt=Qlp...

A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases.

Please let me know if you’d like to be added.

go.bsky.app/5M6obrp