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SeYeon Chung

@seyeonchung.bsky.social

240 followers 390 following 36 posts

Cell and developmental biologist | Associate professor at LSU | Interested in epithelial morphogenesis, tube formation, cytoskeleton, apical ECM | she/her https://faculty.lsu.edu/seyeonchunglab

faculty.lsu.edu

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SeYeon Chung @seyeonchung.bsky.social · 12d

The version of record of our paper is out! 🎉
We show that sulfation is essential for organizing the apical ECM (aECM) during tubulogenesis in Drosophila, and identify ZP domain proteins as key components of the non-chitinous aECM of the salivary gland. 🧬
elifesciences.org/articles/108...

SeYeon Chung @seyeonchung.bsky.social · 12d

The version of record of our paper is out! 🎉
We show that sulfation is essential for organizing the apical ECM (aECM) during tubulogenesis in Drosophila, and identify ZP domain proteins as key components of the non-chitinous aECM of the salivary gland. 🧬
elifesciences.org/articles/108...

SeYeon Chung @seyeonchung.bsky.social · Sep 3

Got the nicest email from a former student who took my Dev Bio class a few years ago and went on to med school. Moments like this remind me why teaching is so meaningful.

SeYeon Chung @seyeonchung.bsky.social · Aug 29

Thanks, Neha!

SeYeon Chung @seyeonchung.bsky.social · Aug 28

Thanks also to all the co-authors, including Rutuparna Joshi, Ying Xiao, and @vvishakha.bsky.social. I couldn’t be prouder of this team and the creative, collaborative spirit that brought this project to life. Also grateful to the NSF and NIDCR at NIH for funding this research.

SeYeon Chung @seyeonchung.bsky.social · Aug 28

And kudos to Jeffrey Matthew @matthewjeffre.bsky.social, co-first author, who expanded and completed the work with great care and rigor. He is now a postdoc at UPenn, studying regeneration.

SeYeon Chung @seyeonchung.bsky.social · Aug 28

A very special shout-out to Luke Woodward, our first author, who began this project as an undergraduate and delivered exceptional results—both in quality and quantity. He is now pursuing his Ph.D. at the University of Chicago, studying heart development.

SeYeon Chung @seyeonchung.bsky.social · Aug 28

We show that the sulfation enzyme PAPS synthetase (Papss) is required for organizing the non-chitinous aECM of the Drosophila salivary gland. We also identify and characterize zona pellucida domain proteins as some of the first known components of this non-chitinous aECM.

SeYeon Chung @seyeonchung.bsky.social · Aug 28

In this study, we uncover the critical role of #sulfation —a key post-translational modification of proteins and proteoglycan side chains—in organizing the apical extracellular matrix (aECM) during tubulogenesis. While the #aECM is essential for tissue development, it is still poorly understood.

SeYeon Chung @seyeonchung.bsky.social · Aug 28

This work was first reviewed by @reviewcommons.org, which has become my favorite way to have a paper reviewed. After a full revision, we transferred the manuscript to @elife.bsky.social, where it is now officially published.

SeYeon Chung @seyeonchung.bsky.social · Aug 28

Our new paper, “Organization of the apical extracellular matrix during tubular organ formation”, has been published in
@elife.bsky.social! elifesciences.org/reviewed-pre...

Organization of the apical extracellular matrix during tubular organ formation

elifesciences.org

Reposted by SeYeon Chung

Katja Röper @katjaroeper.bsky.social · Aug 27

Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/...

Reposted by SeYeon Chung

FlyBase @flybase.bsky.social · Aug 15

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

FlyBase:Contribute to FlyBase - FlyBase Wiki

wiki.flybase.org

SeYeon Chung @seyeonchung.bsky.social · Aug 4

Several of my students also had the opportunity to present their own work and received great feedback. They were so excited and came back with much more enthusiasm and motivation!

SeYeon Chung @seyeonchung.bsky.social · Aug 4

We held the 2nd Fly Bayou Symposium in New Orleans last week—so great to reconnect in person and hear exciting research! What began in 2020 as a small local network has grown to 36 labs across 14 states. Grateful to see this community thrive and support each other! 🪰

SeYeon Chung @seyeonchung.bsky.social · Jul 16

Excited about this new virtual seminar series on the apical ECM!

Pujol lab @pujol-lab.bsky.social · Jul 16

... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social

Reposted by SeYeon Chung

Meera Sundaram @meera-sundaram.bsky.social · May 17

Up on biorxiv! The tour de force protein tagging atlas for the #Celegans cuticle #aECM - from Jordan Ward @gotworms.bsky.social and Andrew Chisholm labs. So many beautiful images of cuticle collagen substructures !! www.biorxiv.org/content/10.1...

Multiscale patterning of a model apical extracellular matrix revealed by systematic endogenous protein tagging

Barrier epithelia are shielded from the external environment by their apical extracellular matrices (aECMs). The molecular complexity of aECMs has challenged understanding of their organization in viv...

www.biorxiv.org

SeYeon Chung @seyeonchung.bsky.social · May 17

Also congratulations to our talented undergraduates, Maggie Wheat (summa cum laude) and Cailyn Lee (College Honors) on their graduation! Can't wait to see what the future holds for them!

SeYeon Chung @seyeonchung.bsky.social · May 17

Congratulations to Dr. Jeffrey Matthew @matthewjeffre.bsky.social! Jeffrey is one of the most talented, dedicated, and kindest people I've ever known. He will start his postdoctoral research in regeneration at the Rompolas lab at UPenn, and i have no doubt he will thrive. Geaux Jeffrey!

SeYeon Chung @seyeonchung.bsky.social · May 17

Great news!! Congratulations, Meera!

SeYeon Chung @seyeonchung.bsky.social · May 12

End of semester lab lunch. It feels like each semester goes by more quickly every year!

SeYeon Chung @seyeonchung.bsky.social · May 6

Amazing! Big congrats, Igor! Well deserved.

SeYeon Chung @seyeonchung.bsky.social · Apr 30

Huge congrats to talented undergraduate Cailyn Lee in the lab on her well-deserved award from the LSU BioSci department. She will start her masters in medical sciences at Tufts this fall and is applying for MD/PhD. So proud and excited for her!

SeYeon Chung @seyeonchung.bsky.social · Apr 25

Excellent presentations from our amazing undergraduate researchers, including my student Cailyn Lee, on their exciting research at #LSUDiscoverDay.

SeYeon Chung @seyeonchung.bsky.social · Apr 18

Thanks, Neha!

SeYeon Chung @seyeonchung.bsky.social · Apr 17

Thank you!