Shao-Liang Zheng
@shaoliangzheng.bsky.social
150 followers 34 following 47 posts
Professional Crystallographer, Crystallography Educator
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shaoliangzheng.bsky.social
This shows what we got from the grander 🥳🥳 #crystallography #education
shaoliangzheng.bsky.social
📢 Join us for #Chem255 @harvard.edu next spring youtube.com/watch?v=Tbqh... 🥳🥳 #crystallography #undergraduate #graduate #education
shaoliangzheng.bsky.social
crystal grinder used to create a sphere-shaped crystal for #ChargeDensityAnalysis 😀 #crystallography #education
shaoliangzheng.bsky.social
A great approach: "analysis of #CrystalStructures in science classes at #HighSchools offers a wide range of opportunities for illustrating and improving understanding of fundamental #StructuralChemistry concepts"😀 doi.org/10.1107/S160...
@japplcryst.iucr.org #K12 #crystallography #Education
Crystallography in school
Preconditions and applications for teaching crystallography in high school chemistry classes are presented.
doi.org
shaoliangzheng.bsky.social
Sean shares a strategy for handling unusual #WeightingSchemes sometimes encountered in #StructureRefinements with #SHELXL 🥳🥳
doi.org/10.1107/S205...
@actacryste.iucr.org #crystallography #education
shaoliangzheng.bsky.social
Richard describes #CrystalGrowth for X-ray #diffraction, a cornerstone of hands-on learning in #StructuralChemistry. 🥳🥳 doi.org/10.1107/S205...
@actacryste.iucr.org #crystallography #education
shaoliangzheng.bsky.social
Dilek, Meghan & Christina present a new instructional #module designed to inspire #undergraduates in #chemistry and #StructuralScience🥳🥳 doi.org/10.1107/S205...
@actacryste.iucr.org #crystallography #education
shaoliangzheng.bsky.social
What kind of the machine you used?🤔
shaoliangzheng.bsky.social
Sure. Glad that you find them useful 😀 Best of luck with the Duffy proposal!
shaoliangzheng.bsky.social
We also shared #K12 and outreach sample examples here 😀 😀 : doi.org/10.1107/S160... @japplcryst.iucr.org #IUCr #crystallography #outreach
doi.org
shaoliangzheng.bsky.social
📢Excited to share how we’re making #crystallography
accessible to #undergrads & #K12, helping inspire the next generation! #NEACT2025 bit.ly/NEACT2025 😀😀 #ScienceEducation #STEMTeachers #StructuralScience #education #ProfessionalDevelopment #TeacherPD
shaoliangzheng.bsky.social
Preparing a presentation for #ACA2025 "Engaging Students with Crystallography" session to share our new #Insights & #BestPractices for chemistry #undergraduate & #graduate @harvard.edu 🥳 doi.org/10.1021/acs.... @pubs.acs.org @acastructuralsci.bsky.social #crystallography #education #Twin #disorder
shaoliangzheng.bsky.social
Honored to contribute to this open-access paper and share how making small-molecule #crystallography accessible through experiential learning enhances #chemistry education 🙌 #StructuralScience #K12 #outreach #undergrad #education #graduate #research
shaoliangzheng.bsky.social
A student is asking a good question: "Has the #isolated carbon(I) species featuring a #CarboneCationRadical truly been 'unambiguously established by single-crystal X-ray diffraction', given that the #EPR was done in THF?" 🤔🤔 nature.com/articles/s44... #crystallography #education
shaoliangzheng.bsky.social
📢How #photocrystallography can help your research: "Merging cryogenic #photochemistry with #SingleCrystal reaction environments provides a #unique opportunity for molecular synthesis of reactive species." pubs.acs.org/doi/10.1021/... 🥳 #crystallography #education
<italic toggle&#x3D;"yes">In Crystallo</italic> Photochemistry: Reimagining Synthetic Tractability with Transparent Single-Crystalline Flasks
Expanding the boundaries of synthetic tractability ─ of what molecules can be synthesized and isolated ─ is an eternal challenge for synthetic chemists. The development of new synthetic methods and strategies enables the properties and potential functions of novel molecular targets to be experimentally evaluated. In the context of catalysis, predictable synthetic strategies are often available to access kinetically persistent intermediates such as catalyst resting states. In contrast, synthesis and characterization of the reactive intermediates are often not possible due to the fleeting lifetimes of these species. In crystallo photochemistry combines single-crystal matrix isolation with cryogenic photochemistry to enable reactive intermediates to be synthesized under conditions in which they are persistent and can be (crystallographically) characterized. This Outlook highlights key achievements of in crystallo photochemistry as well as discusses opportunities and challenges that confront realization of the potential of in crystallo synthesis to redefine the boundaries of synthetic tractability.
https://pubs.acs.org/doi/10.1021/acscentsci.5c00549🥳#crystallography
shaoliangzheng.bsky.social
Did you check the NMR or MS by re-disolving the crystals?🤔
shaoliangzheng.bsky.social
Based on the solution, there should be three target molecules, but they simply deleted other two😂😂
shaoliangzheng.bsky.social
This was also my student's first reaction, so he downloaded the CIF and figured out what had gone wrong. 😀Yes, the original R1 is 0.98. 😂
shaoliangzheng.bsky.social
While prepping for group meeting, a student spotted a structure with R1 = 0.9813 (!) in pubs.acs.org/doi/10.1021/... @ccdc.cam.ac.uk 😱 and used what he learned in #Chem255 to refine it to R1 < 0.06—after squeezing out mystery solvents. What an achievement! 🥳 #crystallography #education