The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their groundbreaking discoveries on peripheral immune tolerance, a mechanism that prevents the body’s immune system from attacking its own cells.Announced on Monday by Sweden’s Karolinska Institute, the award recognises decades of research that deepened understanding of autoimmune diseases and paved the way for new treatments in immunology and cancer therapy.

Many Chinese researchers have received enviable benefits and positions after returning from training abroad.

The best results come when a human and the model work together.

Early-career researchers’ access to neutron-beam instruments jumped from 61% to 78% at one Australian facility.

The journal Science retracts a headline-grabbing study, but the authors vigorously defend their data and say the retraction is unwarranted.

Gavi, the vaccine provider for the world’s poorest people, needs an extra US$3 billion to protect infants and other vulnerable groups. More donors must step up.

Families with three or more boys, for example, are more likely to have another boy than a girl as the next child.

Current procedures for reviving a heart for transplant are ethically fraught or expensive.

Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria.

Massive proteomics database links gene variant APOE4 to chronic inflammation.

Nature - These sophisticated models will be used for human-development studies and drug testing.

When hunter-gatherers began living close to animals, the pathogens that cause the plague and leprosy got closer too.

Brain–computer interfaces being trialled in China offer some advantages over Neuralink and other leading US devices.

Survey finds law requiring married couples to share the same family name causes havoc for researchers.

Abstracts included telltale words, such as ‘unparalleled’ and ‘invaluable’, that are common in text generated by large language models.

The decades-old limit on how long human embryos can be grown in culture is under debate. A new road map outlines how to extend the length of culture responsibly.

Studies of the regenerative powers of worms, zebrafish and lizards suggest ways to improve recovery in people.

The hearts started to beat in the pig–human hybrids, which survived for 21 days.

Human cells injected into amniotic fluid find their way into fetal mouse organs.

Critics fear that anti-vaccine leader’s picks for crucial committee will be a ‘disaster for public health’.