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Reposted by Sonia Garcia-Ruiz

Mike Pitts @pittsmike.bsky.social · Jan 24

At last: a Stonehenge story that is exactly what it says: Simon Banton, Tim Daw and Mark Bowden (left to right... http://bit.ly/1qTYhXe

At last: a Stonehenge story that is exactly what it says

The new Antiquity has a paper by Simon Banton, Mark Bowde...

bit.ly

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Sonia Garcia-Ruiz @soniagr.bsky.social · May 17

Marvellous artefact that formed part of the front of a canoe. Made of wood, the crocodile eyes are represented by fine china cups. Seen at the Museum of Anthropology in Cambridge. #happysaturday

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Sonia Garcia-Ruiz @soniagr.bsky.social · Apr 27

Congratulations 🎊 👏 💐 🥳

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Instituto de Agricultura Sostenible @iascsic.bsky.social · Mar 31

👉 @same18-bcn.bsky.social @ramalok.bsky.social
@microbiomacsic.bsky.social @ice-csic.bsky.social @soniagr.bsky.social @itq-upvcsic.bsky.social @sribo.bsky.social @sebbm.bsky.social y @esanchezsanchez.bsky.social
👋👋 ¡Gracias por seguirnos! 👋👋
#cienciaparalaagricultura

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Jack Humphrey @jack-humphrey.bsky.social · Mar 4

Ecstatic to see our paper "Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing" now published in @naturegenet.bsky.social with @trajnp.bsky.social and @panosroussos.bsky.social @sinaibrain.bsky.social www.nature.com/articles/s41...

Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing - Nature Genetics

This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known and...

www.nature.com

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Selina Wray @selinawray.bsky.social · Mar 4

Extraordinary man.

If you can, donate blood 🩸 it takes 30 mins and saves lives 🙏🏻

Trish Greenhalgh @trishgreenhalgh.bsky.social · Mar 4

The most extraordinary thing about James Harrison, who donated his rare plasma every 2 weeks for over 60 years and saved the lives of an estimated 2.4 million babies, is that he had to overcome a FEAR OF NEEDLES.

www.independent.co.uk/news/world/a...

James Harrison, whose rare blood helped save millions of babies, dies at 88

By donating blood over 1,100 times, James Harrison helped develop Anti-D, a life-saving treatment for newborns at risk of Rhesus disease

www.independent.co.uk

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Ana Conesa @anaconesa.bsky.social · Mar 4

Thrilled to see our Perspective on long-read transcriptomics Published in Advance in @genomeresearch.bsky.social, with #AdamFrankish and @carolinamonzo.bsky.social. We discuss the opportunities and challenges of LRS to uncover Transcript Divergence and for Genome Annotation. tinyurl.com/bdeteu4j

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Selina Wray @selinawray.bsky.social · Feb 25

This was so powerful - few of us can imagine the reality of having a family devastated by familial FTD - and the response of Jordan/Cian to their own risk is incredibly inspiring. Find them in instagram/TikTok as the FTD Brothers and follow their story…!

Susan Kohlhaas @aruk-susank.bsky.social · Feb 25

@alzheimersresearchuk.org supporter Jordan Adams opens our research conference.

Jordan speaks so passionately about his mum’s diagnosis and journey with Frontotemporal Dementia, his own risk of developing it and why he’s relentlessly raising money for dementia research.

Unbelievably inspiring 🧡

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Cambridge RNA @cambridgerna.bsky.social · Feb 21

Yesterday’s Cambridge RNA Club was a blast! Despite a small crowd, we had great science, lively discussions and, of course… pizza! Quality over quantity, right? Huge thanks to @vanessaloi.bsky.social @soniagr.bsky.social & sponsors for making it a fantastic session! See you at the next one!

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Cambridge RNA @cambridgerna.bsky.social · Feb 13

🎤 Excited to learn how RNA splicing is linked to Alzheimer’s? @soniagr.bsky.social (UK Dementia Research Institute) will unveil insights from single-nucleus RNA-seq at the Cambridge RNA Club!
Join us for cutting-edge science & stay for networking 🍕on 20th Feb at 17h in @cambiochem.bsky.social

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Cambridge RNA @cambridgerna.bsky.social · Feb 17

📢 Reminder! This Thursday at 17:00, join us for an exciting session of Cambridge RNA Club with @soniagr.bsky.social and @vanessaloi.bsky.social
📍 Sanger building @CamBiochem
🍕 Networking after with pizza, snacks & drinks!
Sponsored by @rnasociety.bsky.social , Lexogen, NEB & 2BScientific

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Sonia Garcia-Ruiz @soniagr.bsky.social · Feb 15

It is really cold out there! I would rather prefer to stay warm and cozy at home. Happy #caturday folks!

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Sonia Garcia-Ruiz @soniagr.bsky.social · Feb 8

The magnificent Magna Carta, a royal charter of rights agreed to by King John of England on 15 June 1215. It limited the rights of the King by declaring him to be subject to the rule of law. It provided the foundation for individual rights. On display at the British Library #magnacarta

Sonia Garcia-Ruiz @soniagr.bsky.social · Feb 1

Happy #Caturday folks!

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

Wow, I love it!

Reposted by Sonia Garcia-Ruiz

Ana Conesa @anaconesa.bsky.social · Jan 27

Precioso reportaje sobre el mural que la pintora Clara Gomez Campos me ha pintado en mi barrio, Benimaclet.
disfrutabenimaclet.com/2025/01/27/e...

El mural que homenajea a la investigadora Ana Conesa en Benimaclet

La investigadora Ana Conesa ya tiene en su barrio, Benimaclet, un mural que la homenajea. Lo ha creado Clara Gómez dentro del proyecto ‘Dones de ciència’.

disfrutabenimaclet.com

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

6) This has been an extensive collaborative team effort! Thanks to @jwbrenton.bsky.social MelissaGrant-Peters ZhongboChen EmilKGustavson ReginaHReynolds @lcolladotor.bsky.social
AineFairbrother-Browne and many more from our lab (RytenLab rytenlab.xn--com)-876aaa40307gka16qcac854l97a7k

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

5) Overall, this in-depth characterisation of splicing accuracy can expand our understanding of the role of inaccuracies in ageing and neurodegenerative disorders.

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

4/ Key findings 🔑 3) We observe a genome-wide increase in splicing inaccuracies in samples affected with Alzheimer’s disease compared to neurologically normal individuals. 🧠

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

3) Key findings 🔑 2) We find that age is positively correlated with a global decline in splicing fidelity, mostly affecting genes implicated in neurodegenerative diseases. 💆‍♂️ #ageing #splicingnoise #splicingaccuracy #neurodegeneration

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

2) Key findings 🔑1) We show that splicing inaccuracies occur at different rates across introns and tissues and are affected by the abundance of core components of the spliceosome assembly and its regulators. #RNAbindingProteins #NMDpathway

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

1) Methods📝 We investigate splicing accuracy using short-read RNA-sequencing data from >14k control samples and 40 human body sites, focusing on split reads that partially map to known transcripts in the reference annotation.

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 27

New in @naturecomms.bsky.social: I'm thrilled to share with you our latest work that applies #srRNAseq to understand splicing accuracy across human introns, tissues and in the context of ageing and neurodegeneration www.nature.com/articles/s41...

Splicing accuracy varies across human introns, tissues, age and disease - Nature Communications

Inaccuracies in RNA splicing may play a significant role in aging and disease. Here, the authors present a comprehensive characterization of splicing accuracy across over 14,000 human samples, offerin...

www.nature.com

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Sonia Garcia-Ruiz @soniagr.bsky.social · Jan 26

#dinkydoors Miniature sculpture (with doors), lovingly made and hidden just out of plain sight around Cambridge. This one can be seen in Downing Street Cambridge, which mimicks the real and famous one in London. There are many of them, and they represent cute petite portals into other worlds :)

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Sonia Garcia-Ruiz @soniagr.bsky.social · Dec 1

I can not comprehend the size and scale of the observable universe: roughly 2 trillion galaxies, ~400 billion stars per galaxy (considering the size of the Milky Way). This is just the piece we can observe given the speed of light (it takes over 100,000 years to cross our galaxy! 🤯