sophiebell.bsky.social
Sophie Bell
@sophiebell.bsky.social
74 followers 110 following 6 posts
Clinical psych PhD candidate @ University of Virginia | Alzheimer's disease & cognitive aging | behavioral genetics & epigenetics
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sophiebell.bsky.social
Sophie Bell @sophiebell.bsky.social · 21d
dornsife.usc.edu/news/stories...
What your DNA – and childhood – reveal about midlife brain health
Study of twins finds accelerated biological aging, amplified by early-life disadvantage, is linked to steeper IQ declines by midlife
dornsife.usc.edu
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sophiebell.bsky.social
Sophie Bell @sophiebell.bsky.social · 28d
Grateful to UVA Today for featuring our recent study! And big thanks to the creative mind behind this mildly creepy yet amazing graphic - who knew DNA methylation aging and twins could come together so seamlessly?
news.virginia.edu/content/uva-...
UVA study of identical twins links faster aging to memory decline
Researcher Sophie Bell and professor Eric Turkheimer identified how genetics, environment and biology combine to affect cognitive health.
news.virginia.edu
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sophiebell.bsky.social
Sophie Bell @sophiebell.bsky.social · Sep 8
Thanks for making this PSA 😂
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sophiebell.bsky.social
Sophie Bell @sophiebell.bsky.social · Sep 8
Nice writeup on our paper that was recently published in Aging where we found second generation epigenetic clocks predicted cognitive decline in midlife in the Louisville Twins @ent3c.bsky.social @aging-us.bsky.social
www.psypost.org/biological-a...
Biological aging predicts midlife cognitive decline, especially in those raised in poverty
A new study using twin data indicates that accelerated biological aging predicts cognitive decline from childhood to midlife—especially for those raised in lower-income households. The research sheds ...
www.psypost.org
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Reposted by Sophie Bell
aging-us.bsky.social
Aging-US @aging-us.bsky.social · Jul 30
📈 #TrendingWithImpact:
A new #researchpaper was #published on July 23, titled “Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status.”

🔗 doi.org/10.18632/agi...

#aging #quote #openaccess #publishing #twins #DNAMethylation
Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status
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Reposted by Sophie Bell
ent3c.bsky.social
Eric Turkheimer @ent3c.bsky.social · Jul 23
New paper with first author @sophiebell.bsky.social. We show that epigenetic clocks predict decline in IQ between adolescence and midlife, between and within twin pairs, and that the effect is stronger among people from low SES backgrounds. A Scarr-Rowe-adjacent effect. www.aging-us.com/advance
Graph illustrating interaction effect whereby epigenetic clocks predict IQ decline more strongly in twins from low SES backgrounds.
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sophiebell.bsky.social
Sophie Bell @sophiebell.bsky.social · Jul 6
Another great BGA meeting in Atlanta.. glad to keep the lab tradition going @ent3c.bsky.social!
ent3c.bsky.social
Eric Turkheimer @ent3c.bsky.social · Jul 2
In other news from the BGA meeting @sophiebell.bsky.social won the award for best student oral presentation. I think my lab is firmly in the lead for student awards, BGA-wide. Gifted students have always been my secret sauce.
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sophiebell.bsky.social
Sophie Bell @sophiebell.bsky.social · May 30
Major congrats to our colleagues at USC!! The 5ADCSI test for Alzheimer's disease blood biomarkers is now validated and published in Journal of Alzheimer's Disease. The 5ADCSI is a low-cost, sensitive assay capturing plasma amyloid-β, pTau, NfL, and GFAP:

journals.sagepub.com/doi/10.1177/...
High precision and cost-effective multiplex quantification of amyloid-β40, amyloid-β42, p181Tau, p217Tau, neurofilament light chain, and glial fibrillary acidic protein from plasma and serum - Farshad...
Background Current methods to quantify blood biomarkers for Alzheimer's disease (AD) are expensive and are not widely available. Objective To develop a lo...
journals.sagepub.com