Sourav Acharya
@souravacharya1.bsky.social
Postdoc @Hebrew University of Jerusalem; PhD @IISER Kolkata: Inorganic Medicinal Chemistry, Metallodrugs, Anticancer agents.
Excited to share our latest publication in the Journal of Medicinal Chemistry.
We developed Pt(IV) prodrugs that combine cisplatin or oxaliplatin cores with ALK inhibitors (crizotinib or ceritinib) to tackle ALK-rearranged non–small cell lung cancer (NSCLC).
Please check out the open access article.
We developed Pt(IV) prodrugs that combine cisplatin or oxaliplatin cores with ALK inhibitors (crizotinib or ceritinib) to tackle ALK-rearranged non–small cell lung cancer (NSCLC).
Please check out the open access article.
Crizotinib- or Ceritinib-Conjugated Platinum(IV) Prodrugs As Potent Multiaction Agents Inducing Antiproliferative Effects in 2D and 3D Cancer Cell Models
Novel Pt(IV) complexes conjugated with the kinase inhibitors crizotinib or ceritinib were synthesized and assessed for anticancer activity. Cisplatin-derived derivatives bearing phenylbutyrate and eit...
pubs.acs.org
November 10, 2025 at 2:02 PM
Excited to share our latest publication in the Journal of Medicinal Chemistry.
We developed Pt(IV) prodrugs that combine cisplatin or oxaliplatin cores with ALK inhibitors (crizotinib or ceritinib) to tackle ALK-rearranged non–small cell lung cancer (NSCLC).
Please check out the open access article.
We developed Pt(IV) prodrugs that combine cisplatin or oxaliplatin cores with ALK inhibitors (crizotinib or ceritinib) to tackle ALK-rearranged non–small cell lung cancer (NSCLC).
Please check out the open access article.
Reposted by Sourav Acharya
👏Le groupe du Pr. Gilles Gasser @gassergroup.bsky.social & le Pr. Dan Gibson ont conçu un conjugué métallique à triple action:
💡 photothérapie
⚡ chimiothérapie ciblée
🧬 stimulation immunitaire
➡️ Toutes les infos ici : urlr.me/d8A3ym
@psl-univ.bsky.social
💡 photothérapie
⚡ chimiothérapie ciblée
🧬 stimulation immunitaire
➡️ Toutes les infos ici : urlr.me/d8A3ym
@psl-univ.bsky.social
October 6, 2025 at 2:54 PM
👏Le groupe du Pr. Gilles Gasser @gassergroup.bsky.social & le Pr. Dan Gibson ont conçu un conjugué métallique à triple action:
💡 photothérapie
⚡ chimiothérapie ciblée
🧬 stimulation immunitaire
➡️ Toutes les infos ici : urlr.me/d8A3ym
@psl-univ.bsky.social
💡 photothérapie
⚡ chimiothérapie ciblée
🧬 stimulation immunitaire
➡️ Toutes les infos ici : urlr.me/d8A3ym
@psl-univ.bsky.social
I am excited to share our latest collaborative work with Prof. Jonathan Sessler’s group, now published in Angewandte Chemie! A Pt(IV) complex linked with Ru(II)-p-cymene and Au(I) centers inducing immunogenic cell death (ICD) against cancer.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Three Is Better than One: A Multimetal Complex that Triggers Immunogenic Cell Death
A triple metal prodrug that codelivers PtII, RuII, and AuI species triggers a potent immunogenic cell death (ICD) response via combined Type I/II pathways. The tri-metallic scaffold promotes tumor in...
onlinelibrary.wiley.com
August 12, 2025 at 12:28 PM
I am excited to share our latest collaborative work with Prof. Jonathan Sessler’s group, now published in Angewandte Chemie! A Pt(IV) complex linked with Ru(II)-p-cymene and Au(I) centers inducing immunogenic cell death (ICD) against cancer.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...