Our Simon Lam developed the user-friendly web portal to freely share this map of interactions, spidrweb.org, making this a global resource for all, to help identify therapeutic targets for cancer and other DDR-related diseases.
Thrilled to see this “veritable tour de force” led by John_C_Fielden from Jacob Corn lab out @nature.com, rdcu.be/ehd4E. This @erc.europa.eu funded project uses #CRISPRi to systematically scan 548 DDR genes for synthetic lethal interactions, ~150,000 pairwise combinations!