Stainier Lab
@stainierlab.bsky.social
110 followers 11 following 3 posts
Our lab studies #development #regeneration #geneticrobustness @mpi_hlr. The account is run by various lab members. Website- https://www.mpi-hlr.de/developmental-genetics
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stainierlab.bsky.social
Congratulations to Samuel Capon and coauthors on their latest study that dives into the fascinating world of phenotypic variation in Fibronectin mutants, exploring why the exact same mutation leads to different viability during embryonic development ! 🥳🎉

journals.plos.org/plosgenetics...
A genetic modifier links integrin α5 to the phenotypic variation in fibronectin 1a mutant zebrafish
Author summary Recent studies have identified apparently healthy individuals with mutations that would be expected to lead to disease. Why these individuals are disease resistant is not understood. St...
journals.plos.org
Reposted by Stainier Lab
stemcellreports.bsky.social
The newest podcast is now live. Listen here tinyurl.com/ej429twb or wherever you download your favorite podcast.

@isscr.org @stainierlab.bsky.social @mingxiagu.bsky.social @uclastemcell.bsky.social
stainierlab.bsky.social
Paper alert! Congrats to Lara, @cmdooley.bsky.social , @douglasadamoski.bsky.social and Thomas Juan for their great work on identifying the first example of Transcriptional Adaption in humans!🎉
cmdooley.bsky.social
1/? 🧬 New Breakthrough in Duchenne Muscular Dystrophy (DMD)!
Our new paper in
@Nature
reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss.
[🔗 Link: www.nature.com/articles/s41...
https://www.nature.com/articles/s41586-024-08539-x]
stainierlab.bsky.social
Stainier lab alumni, Save The Date!
30th anniversary celebration of the Stainier lab will take place in Bad Nauheim from Sunday to Wednesday, 6-9 April 2025.
Please block your calendar and spread the word about this scientific and social gathering.
More details to follow!