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stefvass.bsky.social
Stephane Vassilopoulos
@stefvass.bsky.social
1.2K followers 590 following 35 posts
Cell biologist @INSERM @Sorbonne_Univ_, clathrin, dynamin, neuromuscular diseases, electron microscopy, metal replicas #CLEM 🔬🇪🇺 🇬🇷 🇨🇵
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stefvass.bsky.social
Stephane Vassilopoulos @stefvass.bsky.social · Nov 26
One of my favorite images: a platinum replica electron microscopy shot of an unroofed cancer cell migrating along collagen fibers (blue). It beautifully captures the clathrin-coated pits (red, ~100 nm) and the intricate network of branched actin filaments (orange) 🔬
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · 5d
Want to hear a mid-career PI pontificate about science, career and cooking? Today's your lucky day thanks to The Microscopists podcast! Thanks Peter @yorkbioimaging.bsky.social for having me 🎙️🎧
themicroscopists.bitesizebio.com/episodes/chr...
The Microscopists | Christophe Leterrier (CNRS & Aix-Marseille Université)
This time on The Microscopists, we're joined by Christophe Leterrier, team leader at NeuroCyto in Marseille and director of a Nikon Center of Excellence for super-resolution microscopy.Christophe r...
themicroscopists.bitesizebio.com
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · 22d
New NeuroCyto preprint about to drop! @wiesner-t.bsky.social 😎⏳
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Reposted by Stephane Vassilopoulos
membramics-lab.bsky.social
MOREL Lab / MEMBRAMICS research @membramics-lab.bsky.social · Sep 8
www.sciencedirect.com/science/arti...

check out the recent dispatch on endolysosomes and melano-biology interplay in @currentbiology.bsky.social by @delevoyecedric.bsky.social & @laurasalavessa.bsky.social from @membramics-lab.bsky.social
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Reposted by Stephane Vassilopoulos
myelincentric.bsky.social
Hauke Werner @myelincentric.bsky.social · Sep 3
If you're interested in trafficking of #myelin constituents in #oligodendrocytes, and of course you are, you may want to check out our new preprint. It's very nice PhD work by @sophiesiems.bsky.social, and we're grateful to all who contributed!

www.biorxiv.org/content/10.1...
Adaptor protein complex 2 (AP2) participates in biogenesis and homeostasis of myelin sheaths in the central nervous system
Myelination of CNS axons requires oligodendrocytes to undergo extensive morphological changes by producing large amounts of myelin membrane with defined protein composition and structure. The formatio...
www.biorxiv.org
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · Aug 13
Happy to contribute to this new work from @micoxscopy.bsky.social et al, helping apply SSQUASH to analyse the shape of spectrin rings along axons. Data analysis is the next frontier in SMLM, and I'm always up for chatting, sharing data and see how we can push things further!
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stefvass.bsky.social
Stephane Vassilopoulos @stefvass.bsky.social · Aug 12
how did I miss this fantastic paper...congrats Marko @kaksonen.bsky.social and team!!
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stefvass.bsky.social
Stephane Vassilopoulos @stefvass.bsky.social · Jul 8
Diving into "le AIS"🤿
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Reposted by Stephane Vassilopoulos
kaksonen.bsky.social
Marko Kaksonen @kaksonen.bsky.social · Jul 7
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).

Please apply and/or repost!

jobs.unige.ch/www/wd_porta...
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Reposted by Stephane Vassilopoulos
kaksonen.bsky.social
Marko Kaksonen @kaksonen.bsky.social · Jun 24
How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...
Localization of WDS proteins and fimbrin in three fungal species.
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stefvass.bsky.social
Stephane Vassilopoulos @stefvass.bsky.social · Jun 22
Congrats Markku!!💥
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Reposted by Stephane Vassilopoulos
mhakala.bsky.social
Markku Hakala @mhakala.bsky.social · Jun 22
I'm grateful for the Research Council of Finland for granting me the Academy Research fellowship! After getting over the shock I will soon move back to Finland to start as a group leader at the Institute of Biotechnology @helsinki.fi. Looking for a PhD student soon! www.aka.fi/en/about-us/...
RCF winter call results: funding decisions in biosciences, health and environmental research
The Research Council of Finland’s Scientific Council for Biosciences, Health and the Environment has granted funding for 38 Academy Research Fellowships, 12 Clinical Researchers and 76 Academy P...
www.aka.fi
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stefvass.bsky.social
Stephane Vassilopoulos @stefvass.bsky.social · Jun 17
💥 Very cool science session at the @academiesciences.bsky.social with @christlet.bsky.social for the "Grandes avancées Françaises en biologie"
🎖prize to @florianwerner.bsky.social and @moparthisk.bsky.social

Check out the live stream here
m.youtube.com/watch?v=PIWI...
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · Jun 17
Honored to be on stage this morning @academiesciences.bsky.social for the work done with @florianwerner.bsky.social and @moparthisk.bsky.social. Also celebrating almost ten years of collaboration and friendship with @stefvass.bsky.social, merging microscopies to discover new biology 🤝
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Reposted by Stephane Vassilopoulos
francois-devred.bsky.social
François Devred @francois-devred.bsky.social · Jun 17
Fierté de DU @inp-marseille.bsky.social : voir les travaux de Florian Werner et Satish Moparthi avec @christlet.bsky.social @stefvass.bsky.social aux 20 ans des grandes avancées françaises en biologie @academiesciences.bsky.social
Bravo à eux !
@cnrsbiologie.bsky.social @univ-amu.fr @cnrs.fr
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · Jun 16
🎉 It's such a pleasure to congratulate Nicolas Jullien, full-stack ingénieur, CRISPR wizard in the NeuroCyto team, software developer extraordinaire and more, who was awarded the @cnrs.fr crystal medal! Thank you @nico-juulien.bsky.social 🙏https://www.insb.cnrs.fr/fr/personne/nicolas-jullien/
Nicolas Jullien
www.insb.cnrs.fr
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Reposted by Stephane Vassilopoulos
cnrs.fr
CNRS @cnrs.fr · Jun 12
#Communiqué 🗞️ Des scientifiques ont réalisé une avancée majeure dans le traitement d’une maladie musculaire génétique grave pour laquelle il n'existe actuellement aucune thérapie, la myopathie centronucléaire liée à la mutation du gène BIN1.

👉 www.cnrs.fr/fr/presse/un...
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · Jun 5
Acknowledgments slide done! Time to rehearse for @academiesciences.bsky.social
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Reposted by Stephane Vassilopoulos
steveroyle.bsky.social
Stephen Royle @steveroyle.bsky.social · Jun 5
This is a summary of our recent @jcellsci.bsky.social paper.

If you've ever wondered why ATG9A has many and varied roles, we think it's because it is trafficked by a subset of a large, diverse family of vesicles - intracellular nanovesicles.

doi.org/10.1242/jcs....
ATG9A vesicles are a subtype of intracellular nanovesicle
Highlighted Article: Presentation of the first intracellular nanovesicle (INV) proteome, showing that a subset of INVs are ATG9A vesicles. This places ATG9A vesicles in a broader superfamily of traffi...
doi.org
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · May 23
This will be at the Académie des Sciences on June 17th, for the 20th anniversary of the “Grandes Avancées Françaises en Biologie” prize. More info here: www.academie-sciences.fr/en/node/2699
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stefvass.bsky.social
Stephane Vassilopoulos @stefvass.bsky.social · May 23
💥🔬💥
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · May 23
Super happy to announce that together with @stefvass.bsky.social , we will have the honor to join 1st authors Florian Wernert and @moparthisk.bsky.social to present our recent work (www.science.org/doi/10.1126/...) to the French Academy of Sciences @academiesciences.bsky.social!
The actin-spectrin submembrane scaffold restricts endocytosis along proximal axons
Clathrin-mediated endocytosis has characteristic features in neuronal dendrites and presynapses, but how membrane proteins are internalized along the axon shaft remains unclear. We focused on clathrin...
www.science.org
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Reposted by Stephane Vassilopoulos
clubexo-endo.bsky.social
Club Exo Endo @clubexo-endo.bsky.social · May 7
Great talks these two last days, including Marc Bitoun (Institut de Myologie, Paris) as keynote speaker who showed impressive data on allele-specific silencing therapy for centronuclear myopathy due to dyn2 mutations.
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · May 6
Congrats @wiesner-t.bsky.social who gave a great talk at the Exo-Endo Meeting yesterday, showing how the acitn-spectrin scaffold regulates exocytosis along the axon shaft!
clubexo-endo.bsky.social
Club Exo Endo @clubexo-endo.bsky.social · May 6
The 27th Club Exo-Endo meeting has started at Fort-Mahon.
exoendo.org/evenement/27...
Nice place, nice talks and congratulation to young researchers who made great talks!!
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Reposted by Stephane Vassilopoulos
mattmuscleguy.bsky.social
Matthew Alexander, PhD @mattmuscleguy.bsky.social · Apr 21
Interesting new #NatureNeuro paper: Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes. #Myoblue tinyurl.com/ysvwdejm
Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes - Nature Neuroscience
Sznajder et al. identified a molecular link between autism and myotonic dystrophy, showing that a tandem repeat mutation in a single gene can disrupt splicing of multiple autism-related genes during b...
tinyurl.com
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Reposted by Stephane Vassilopoulos
drubin.bsky.social
David Drubin @drubin.bsky.social · Apr 9
Congrats to my fantastic coauthors on this work with a surprising conclusion. www.biorxiv.org/content/10.1...
Force-insensitive myosin-I enhances endocytosis robustness through actin network-scale collective ratcheting
Force production by Type-I myosins influences endocytic progression in many cell types. Since different myosin-I isoforms exhibit distinct force-dependent kinetic properties, it is important to invest...
www.biorxiv.org
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Reposted by Stephane Vassilopoulos
christlet.bsky.social
Christophe 🔬 L @christlet.bsky.social · Apr 9
We have a new review out! In this Microscopy & Microanalysis piece, Louisa Mezache and I survey some of the latest commercially available microscope technologies: Nikon NSPARC, Re-scan Gaia, CSR Biotech MI-SIM, refinements to STED, SMLM from Bruker and Abbelight… Check it out with free access:
Advancing Super-Resolution Microscopy: Recent Innovations in Commercial Instruments
Abstract. Super-resolution microscopy techniques have accelerated scientific progress, enabling researchers to explore cellular structures and dynamics wit
academic.oup.com
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