LKB1 (STK11)
@stk11.bsky.social
The authors also show in vivo protection against IgE-mediated anaphylaxis, hinting that AMPK agonists could be a real therapeutic avenue.
November 24, 2025 at 2:58 AM
The authors also show in vivo protection against IgE-mediated anaphylaxis, hinting that AMPK agonists could be a real therapeutic avenue.
What’s striking is how zingerone works. By boosting LKB1/AMPK signaling, it reins in mast cell activation at the source, lowering Ca²⁺ influx, reducing granule release, and dampening the whole allergic cascade. It’s a metabolic lever with immunological consequences.
November 24, 2025 at 2:57 AM
What’s striking is how zingerone works. By boosting LKB1/AMPK signaling, it reins in mast cell activation at the source, lowering Ca²⁺ influx, reducing granule release, and dampening the whole allergic cascade. It’s a metabolic lever with immunological consequences.
