🚀Excellent follow-up by Stephen extending Probability Flow Inference to account for cell proliferation. SOTA performance on time-resolved scRNA-seq to infer transcriptional flow dynamics.
5/5 In summary, even in complex cellular organelles like the spindle, active-matter physics combined with carefully measured data yields predictive theories.
4/5 Our model reveals that spindle organization is governed by: local MT alignment interaction, diffusive-like motion, directed transport & MT turnover dynamics, all encoded in our continuum theory with interpretable and measurable parameters.
3/5 We demonstrate that a simple coarse-grained active liquid crystal model can quantitatively explain both the mean structure and fluctuation spectra of the spindle microtubule network.
"Active Liquid Crystal Theory Explains the Collective Organization of Microtubules in Human Mitotic Spindles". Joint work with Colm Kelleher (now at Syracuse, previously Harvard) @flatironinstitute.org
🚀Excellent follow-up by Stephen extending Probability Flow Inference to account for cell proliferation. SOTA performance on time-resolved scRNA-seq to infer transcriptional flow dynamics.
Mark your calendars!! 🗓️ The third Young Biophysicists Meeting will be held on the coming Monday (May 5th) from 11am - 12pm EST. We have four exciting talks lined up for you, see you all soon! Find out more : shorturl.at/4oKNe
We are announcing the 2nd biophysics summer school in Rethymno, Crete, Greece for undergraduates, MS and PhD students. Please forward to anyone interested! biophysics.materials.uoc.gr Lecturers include: Meredith Betterton, Michael Layden, Surya Maddu, Carl Modes, Tassos Pavlopoulos, Stas Shvartsman
