Lightnews — Scholar-powered news

Syncell Inc @syncellinc.bsky.social · 5d

#Microscoop Mint can label cells or organelles with photobiotinylation in fractions of a second. Below shows stress granules at 40X resolution being photo-labelled in real-time!

We can biotin tag all the proteins contained in these organelles and discover and identify all the proteins using LC/MS.

Syncell Inc @syncellinc.bsky.social · 7d

🚀 Heading to EMBL: Spatial Biology – the Melting Pot this October?
Don’t miss Syncell’s talks on how Microscoop® is transforming spatial proteomics with truly unbiased, hypothesis-free discovery.

#SpatialProteomics #Microscoop #SpatialBiology #EMBL2025

Syncell Inc @syncellinc.bsky.social · 8d

Microscoop® enables spatial proteomics at the highest resolution—helping researchers uncover more disease-relevant targets faster, with subcellular precision and without prior assumptions.

#SpatialProteomics #DrugDiscovery #Microscoop

1

Syncell Inc @syncellinc.bsky.social · 12d

🌟 Meet Tina Chong, our Senior Applications Manager! She bridges customer goals with Microscoop workflows—helping uncover proteins that matter in cancer research.

#Proteomics #TeamSyncell

1

Syncell Inc @syncellinc.bsky.social · 13d

Excited to expand our trusted distributors' network: #Aurogene Srl in Italy, #Velgen Technik in Singapore and Southeast Asia, #Accela in Eastern Europe, and #Biostar in South China.

👉 Learn more about our Partner Network: www.syncell.com/preferred-pa...

Syncell Inc @syncellinc.bsky.social · 15d

✨ What if you could identify primary cilia proteins with high specificity?

The Microscoop® platform makes it possible—uncovering new insights into ciliary structure, function, and their role in health and disease.

📄 Discover the science in our latest whitepaper: www.syncell.com/whitepaper-u...

Syncell Inc @syncellinc.bsky.social · 19d

Map organelle proteomes with subcellular precision.From cilia, mitochondria, to endsomes and more, Microscoop® offers unparalleled insights into organelle-specific proteomes.

#SpatialProteomics #OrganelleBiology #Microscoop

2

Syncell Inc @syncellinc.bsky.social · 23d

🔬 Rethinking Drug Discovery

95% of drugs target proteins, yet thousands of druggable proteins remain untapped. Spatial proteomics is changing this by revealing proteins in their native spatial context—unlocking hidden mechanisms and de-risking R&D pipelines.

👉 www.syncell.com/uncategorize...

Targeting Disease Sites: How Spatial Proteomics Is Rewiring Drug Discovery | Syncell Inc

The human genome encodes ~20,000 protein-coding genes, but only a small fraction of these are currently targeted or considered viable for drug development.

www.syncell.com

1

Syncell Inc @syncellinc.bsky.social · 26d

🔬 Syncell Microscoop is the only unbiased, hypothesis-free spatial proteomics platform—removing assumptions & uncovering the full proteome at subcellular resolution. Discover what others miss. syncell.com/microscoop/ #SpatialProteomics #UnbiasedDiscovery

Syncell Inc @syncellinc.bsky.social · 28d

⏰ Last chance to register for tomorrow’s webinar!
👉https://zoom.us/webinar/register/5117561745218/WN_1_PPv8TXRfW8Yyv6vx2bPw
Don’t miss the opportunity to explore how Microscoop® advances spatial proteomics for unbiased protein discovery in rare and nanoscale structures.

Syncell Inc @syncellinc.bsky.social · Sep 9

Syncell in the Spotlight!
Featured in GenomeWeb, our Microscoop platform is redefining spatial proteomics with unbiased protein discovery at subcellular resolution.
📄 Read the full reprint: genomeweb.com/Reprint-GW25...

#SpatialProteomics #ProteinDiscovery #Microscoop #Syncell

Reprint-GW25007Syncell | GenomeWeb

genomeweb.com

Syncell Inc @syncellinc.bsky.social · Sep 4

Organelle contact sites (mitochondria, ER, Golgi, plasma membrane, etc.) are key for cellular coordination. With Microscoop®, microscopy-guided photo-biotinylation simplifies protein purification at these interfaces—shown here at the mitochondria (TOM20)–lipid droplet (PLIN2) contact site.

1

Syncell Inc @syncellinc.bsky.social · Sep 2

With Microscoop, map the hidden drivers of NAFLD/MASH at nano-resolution and uncover the key proteins fueling disease progression. From steatosis to fibrosis, gain molecular insights no other tech can provide—directly from subcellular contact sites.

BioRxiv
www.biorxiv.org/content/10.1...

1

Syncell Inc @syncellinc.bsky.social · Sep 1

🔬Unbiased protein discovery is now at your fingertips. Learn how you can now map pathway-specific localization & interactions in subcellular structures.

Join our webinar -https://zoom.us/webinar/register/5117561745218/WN_1_PPv8TXRfW8Yyv6vx2bPw

#SpatialProteomics #CellBiology

Syncell Inc @syncellinc.bsky.social · Aug 29

Behind Microscoop Mint’s precision and speed is Tim Kao, creator of Autoscoop—the “brain” that makes discovery seamless.
💡 “Software brings everything together so scientists can focus on discovery, not setup.”
#Syncell #Autoscoop

Syncell Inc @syncellinc.bsky.social · Aug 26

✋ High fives from around the world! 🌎

To celebrate Syncell’s 5th anniversary, our global team came together—virtually—to share the same shirt, the same spirit, and the same excitement for what’s ahead. Grateful for every one of you who make this journey possible. 💙

Syncell Inc @syncellinc.bsky.social · Aug 20

🌍 We’ve just completed a Microscoop installation and training at the Max Planck Institute for Biology of Ageing in Cologne, Germany.
Dr. Hendrik Nolte commented, “We are excited to utilize the Microscoop technology to characterize mitochondria on the subcellular level.”

Syncell Inc @syncellinc.bsky.social · Aug 15

We are delighted to share this latest GenomeWeb article by Adam Bonislawski which expands on Syncell's co-marketing agreement with Thermo Fisher, via interviews with Nikhil Rao, PhD (Syncell) and Bradley Hart (Thermo Fisher).
#SpatialProteomics #MassSpec

www.genomeweb.com/business-new...

With Thermo Fisher Deal, Commercial Expansion, Syncell Pushing Uptake of Spatial Proteomics Tech

The company also plans to launch new reagents for the platform that will enable higher resolution analyses including protein proximity labeling experiments.

www.genomeweb.com

Syncell Inc @syncellinc.bsky.social · Aug 14

We are proud to announce our strategic co-marketing agreement with Thermo Fisher Scientific to advance high-resolution spatial proteomics, reinforcing the mission Syncell's CEO and founder, Jung-Chi Liao, set forth.

www.businesswire.com/news/home/20...

Syncell Inc @syncellinc.bsky.social · Aug 14

Thanks to Bree Foster for interviewing our CCO, Nikhil Rao, PhD and so perfectly profiling our Microscoop technology in this new piece for Drug Discovery News.

Read the article here ➡️ www.drugdiscoverynews.com/a-new-approa...

#spatialproteomics #proteomics #spatialbiology #MassSpec

A new approach to protein profiling in complex tissues

A new imaging-guided sample preparation approach enables unbiased identification of all proteins within precisely defined tissue regions, expanding opportunities for drug discovery.

www.drugdiscoverynews.com

Syncell Inc @syncellinc.bsky.social · Aug 8

#Microscoop, reveal distinct proteomic signatures of astrocytes between the cortex and hippocampus—unbiased, spatially resolved, and directly from fixed tissue. We validate these markers that are differentially expressed based on anatomical location. www.syncell.com/application-...

Syncell Inc @syncellinc.bsky.social · Aug 5

We’re excited to join the 15th International Symposium on Proteomics in the Life Sciences !
📍Catch our poster presentations to explore the latest Microscoop applications
👋 Meet Team Syncell at 3F Exhibit Area
Let’s connect and talk #SpatialProteomics, #MassSpec, and beyond!

Syncell Inc @syncellinc.bsky.social · Aug 1

Cancer doesn’t just grow—it hijacks the nervous system. With Microscoop, map the cancer–nerve interface at nano resolution and identify proteins driving neural invasion and tumor spread. This spatial insight could reveal new targets to disrupt tumor–nerve crosstalk #CancerBiology #SpatialProteomics

Syncell Inc @syncellinc.bsky.social · Jul 29

The Microscoop Mint has discovered a number of proteins that were not known to exist until now in stress granules. We validate these proteins using immunofluorescence for these markers and see that they co-localize with stress granules.
Learn more - www.syncell.com/whitepaper-m...

Syncell Inc @syncellinc.bsky.social · Jul 25

Unlock the hidden drivers of NAFLD/MASH. With Microscoop, map the lipid–mitochondrial interface at nano resolution and uncover the key proteins fueling disease progression. From steatosis to fibrosis, gain molecular insights no other can provide — shorturl.at/IUCFS