SYNTHEMA
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synthemaeu.bsky.social
SYNTHEMA
@synthemaeu.bsky.social
A cross-border hub to develop & validate #AI techniques for anonymization & synthetic data generation in rare hematological diseases 🔬🩸🇪🇺 #HorizonEU project

👉 https://synthema.eu/
How similar is synthetic tabular data to the real thing?

This new approach uses KL and JS divergences to evaluate full joint distributions — not just feature by feature. A more reliable way to validate synthetic datasets in practice.

👉 synthema.eu/publications/

#SyntheticData #DataValidation #AI
December 1, 2025 at 10:52 AM
Over 450 haematological diseases affect blood cells, the lymphatic system & coagulation, posing major challenges to public #HealthSystems.
#SYNTHEMA is developing a secure platform for synthetic #ClinicalData to enable GDPR-compliant research in rare #HaematologicalDiseases.

👉 synthema.eu
November 25, 2025 at 9:27 AM
Can synthetic tabular data be more accurate?

This new model by researchers at Universidad Politécnica de Madrid combines a Variational Autoencoder with a Gaussian Mixture Model. Results outperform #CTGAN and #TVAE, especially on medical datasets.

👉 synthema.eu/publications/

#SYNTHEMA
November 20, 2025 at 9:20 AM
The paper “Distributing trust: A P2P SMPC protocol for secure federated learning” by Petros Demetrakopoulos, Themistoklis Anagnostopoulos and Sofia Tsekeridou (Netcompany RID, #SYNTHEMA partner) will be presented at #FLLM2025 on 27 Nov at 15:30.

synthema.eu
November 17, 2025 at 9:48 AM
#HealthData4EU Cluster is at #EBDVF25 this week. SYNTHEMA isn’t on site, but we’re glad to support tomorrow’s session in Copenhagen. If you're there on 14 Nov, join “Ecosystems of Innovation in Healthcare” from 09:00–10:30, Room 2.B — a chance to hear how our partners advance ethical health data use
November 13, 2025 at 9:16 AM
How well does synthetic data generation work when spread across multiple hospitals? This study on #AML shows that federated learning protects privacy, though fidelity takes a hit. A key step in real-world AI for rare diseases.

👉 synthema.eu/publications

@vicomtech.bsky.social

#SYNTHEMA
November 10, 2025 at 9:49 AM
Two productive days in San Sebastian for the #SYNTHEMA consortium have come to an end. Lively discussions, clear goals for the final year: a recap publication on synthetic data in haematology, joint training with @erneurobloodnet.bsky.social, new papers, and the SYNTHEMA platform launch

synthema.eu
November 6, 2025 at 10:00 AM
The SYNTHEMA consortium is meeting in San Sebastian, Spain, to mark the project’s third anniversary and kick off discussions for the final year ahead. Together, we’re committed to delivering results in secure, AI-powered health data for rare hematological diseases.

👉 synthema.eu
November 4, 2025 at 9:12 AM
What can generative models reveal about the real data they learn from? This study by @upm.es researchers explores membership inference attacks in generative models, introducing new theory and showing how differential privacy fits in. A critical read for privacy-aware AI: synthema.eu/publications/
October 30, 2025 at 8:39 AM
By generating secure, high-quality synthetic data, #SYNTHEMA empowers researchers to push the frontiers of rare-disease research — safely, ethically, and collaboratively.

Learn more: synthema.eu

#AIinHealthcare #RareDiseases #SyntheticData #HorizonEurope
October 28, 2025 at 10:25 AM
SYNTHEMA builds on strong ethical and collaborative foundations:

🩺 @erneurobloodnet.bsky.social – Europe’s rare haematology network

📊Contributions to ENROL, EU RD Platform, and
@radeep.bsky.social

🤝Partnership with Flower - open-source federated learning for privacy-preserving AI
October 28, 2025 at 10:25 AM
We’re validating our methods through two real-world cases:

🩸 Sickle Cell Disease
🧫 Acute Myeloid Leukaemia
AI helping clinicians improve diagnosis, prediction, and personalised care.

#RareDiseases #AIinHealthcare #SCD #AML #SickleCell #Leukaemia
October 28, 2025 at 10:25 AM
Our platform brings together:
🧠 Federated Learning
🔒 Secure Multi-Party Computation
⚖️ Differential Privacy

The result: synthetic data that mimics real patterns without exposing personal information.

#FederatedLearning #SyntheticData
October 28, 2025 at 10:25 AM
SYNTHEMA unites 16 partners from 10 countries to create a cross-border health-data hub for rare haematological diseases.

Together, we’re making data collaboration secure, ethical, and scalable.

#HorizonEurope #ResearchInnovation
October 28, 2025 at 10:25 AM
When data is rare, progress slows. Over 450 blood-related disorders are classified as rare, yet data remains fragmented and inaccessible — limiting progress for 30M+ patients across Europe.

#HealthData #RareDiseases
October 28, 2025 at 10:25 AM
Pushing the boundaries of AI-based research in rare haematological diseases.

#SYNTHEMA develops privacy-preserving AI and synthetic data to create virtual patients that improve diagnosis and treatment in rare diseases.

👉 synthema.eu

#AIinHealthcare #HorizonEurope
October 28, 2025 at 10:25 AM
We’re validating our methods through two real-world cases:

🩸 Sickle Cell Disease
🧫 Acute Myeloid Leukaemia
AI helping clinicians improve diagnosis, prediction, and personalised care.

#RareDiseases #AIinHealthcare #SCD #AML #SickleCell #Leukaemia
October 28, 2025 at 9:49 AM
Our platform brings together:
🧠 Federated Learning
🔒 Secure Multi-Party Computation
⚖️ Differential Privacy

The result: synthetic data that mimics real patterns without exposing personal information.

#FederatedLearning #SyntheticData
October 28, 2025 at 9:49 AM
SYNTHEMA unites 16 partners from 10 countries to create a cross-border health-data hub for rare haematological diseases. 🌍

Together, we’re making data collaboration secure, ethical, and scalable.

#HorizonEurope #ResearchInnovation
October 28, 2025 at 9:49 AM
When data is rare, progress slows. Over 450 blood-related disorders are classified as rare, yet data remains fragmented and inaccessible — limiting progress for 30M+ patients across Europe.

#HealthData #RareDiseases
October 28, 2025 at 9:49 AM
The #HealthData4EU Cluster, which SYNTHEMA forms part of, will host the session “Ecosystems of Innovation in Healthcare: Ensuring Trust, Quality & Ethics in Data Use” at #EBDVF2025 in Copenhagen on 12–14 Nov

Event: european-big-data-value-forum.eu/2025-edition...
Cluster: synthema.eu/healthdata4eu/
October 20, 2025 at 8:50 AM
Most synthetic data models assume data abundance. This study shows how transfer learning and meta-learning improve synthetic data generation for cancer research in low-data scenarios, where real clinical constraints apply.

👉 synthema.eu/publications/

#SYNTHEMA #SyntheticData #AI
October 16, 2025 at 8:21 AM
Our partner i~HD is hosting a special 10th anniversary edition of its Annual Conference: “A Decade of Joining the Dots – Towards Bridging Data Spaces”

📍 3–4 Dec 2025 | Ghent, Belgium

Topics: EHDS, AI in healthcare, data quality, privacy & governance.

👉 www.i-hd.eu/ac2025
October 13, 2025 at 9:52 AM
Most synthetic data models assume data abundance. This study shows how transfer learning and meta-learning improve synthetic data generation for cancer research in low-data scenarios, where real clinical constraints apply.

👉 synthema.eu/publications/

#SYNTHEMA #CancerResearch
October 6, 2025 at 8:25 AM
In #SYNTHEMA, data collection is central to building GDPR-compliant, AI-ready datasets for Sickle Cell Disease and Acute Myeloid Leukaemia. Harmonised across countries, the data supports synthetic generation, federated learning, and future rare disease research.

👉 synthema.eu/2025/09/23/d...
October 2, 2025 at 7:39 AM