Joana Silva
@thejoanasilva.bsky.social
700 followers 360 following 44 posts
Assistant Professor & Group Leader at the UMC-CMM 🇳🇱 silva-lab.org Science and music lover. She/Her
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Reposted by Joana Silva
olivierduss.bsky.social
First paper of our lab today @natureportfolio.bsky.social by Nussi!

We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!

@embl.org #RNAbiology #RNASky

t.co/a24Xxcxdo0
thejoanasilva.bsky.social
This is so important and urgent! Can I please be added @colemanlab.bsky.social? Thank you!
thejoanasilva.bsky.social
Another cool story from @bekkerjensenlab.bsky.social and @annaconstancevind.bsky.social that sheds light on the hidden mechanisms of sunburn.

Turns out UV light doesn’t just damage DNA. It also activates the ribotoxic stress response in skin cells, driving inflammation, cell death and repair!👇
bekkerjensenlab.bsky.social
Time for our first post here 🥳 Our latest paper is online 🙌
We show that UV activates the ribotoxic stress response, which causes inflammation, cell death and thickening in skin. Read about a role for the RSR separate from DNA damage signaling in response to sunburn: ✨☀️ www.cell.com/molecular-ce...
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
The acute skin reaction to sunburn, encompassing keratinocyte cell death, inflammation, and epidermal thickening, has traditionally been ascribed to DNA damage responses. Using a mouse model deficient...
www.cell.com
thejoanasilva.bsky.social
Done :) and thanks for the tip!
thejoanasilva.bsky.social
Pretty sure you do :) Done!
thejoanasilva.bsky.social
I was just looking for this :) Can you please add me? I’m interested in the role ribosomes play in modulating mitochondrial respiration and how this affects cell fate. Thanks!